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Number of items: 131. Tare, Priyanka ; Mallick, Bratati ; Nagaraja, Valakunja (2013) Co-evolution of specific amino acid in sigma 1.2 region and nucleotide base in the discriminator to act as sensors of small molecule effectors of transcription initiation in mycobacteria Molecular Microbiology, 90 (3). pp. 569-583. ISSN 0950-382X Tare, Priyanka ; Nagaraja, Valakunja (2013) Regulation of transcription initiation in mycobacteria Current Science, 105 (5). pp. 632-642. ISSN 0011-3891 Ahmed, W. ; Bhat, A. G. ; Leelaram, M. N. ; Menon, S. ; Nagaraja, V. (2013) Carboxyl terminal domain basic amino acids of mycobacterial topoisomerase I bind DNA to promote strand passage Nucleic Acids Research, 41 (15). pp. 7462-7471. ISSN 0305-1048 Marathe, S. A. ; Kumar, R. ; Ajitkumar, P. ; Nagaraja, V. ; Chakravortty, D. (2013) Curcumin reduces the antimicrobial activity of ciprofloxacin against Salmonella typhimurium and Salmonella typhi Journal of Antimicrobial Chemotherapy, 68 (1). pp. 139-152. ISSN 0305-7453 Vasu, K. ; Nagaraja, V. (2013) Diverse functions of restriction-modification systems in addition to cellular defense Microbiology and Molecular Biology Reviews, 77 (1). pp. 53-72. ISSN 1092-2172 Vasu, K. ; Nagamalleswari, E. ; Zahran, M. ; Imhof, P. ; Xu, S. Y. ; Zhu, Z. ; Chan, S. H. ; Nagaraja, V. (2013) Increasing cleavage specificity and activity of restriction endonuclease KpnI Nucleic Acids Research, 41 (21). pp. 9812-9824. ISSN 0305-1048 Ghosh, S. ; Indi, S. S. ; Nagaraja, V. (2013) Regulation of lipid biosynthesis, sliding motility, and biofilm formation by a membrane-anchored nucleoid-associated protein of Mycobacterium tuberculosis Journal of Bacteriology, 195 (8). pp. 1769-1778. ISSN 0021-9193 Leelaram, M. N. ; Bhat, A. G. ; Godbole, A. A. ; Bhat, R. S. ; Manjunath, R. ; Nagaraja, V. (2013) Type IA topoisomerase inhibition by clamp closure The Faseb Journal, 27 (8). pp. 3030-3038. ISSN 0892-6638 Godbole, Adwait Anand ; Leelaram, Majety Naga ; Bhat, Anuradha Gopal ; Jain, Paras ; Nagaraja, Valakunja (2012) Characterization of DNA topoisomerase I from Mycobacterium tuberculosis: DNA cleavage and religation properties and inhibition of its activity Archives of Biochemistry and Biophysics, 528 (2). pp. 197-203. ISSN 0003-9861 Mitra, Anirban ; Nagaraja, Valakunja (2012) Under-representation of intrinsic terminators across bacterial genomic islands: Rho as a principal regulator of xenogenic DNA expression Gene, 508 (2). pp. 221-228. ISSN 0378-1119 China, A. ; Mishra, S. ; Tare, P. ; Nagaraja, V. (2012) Inhibition of Mycobacterium tuberculosis RNA polymerase by binding of a gre factor homolog to the secondary channel Journal of Bacteriology, 194 (5). pp. 1009-1017. ISSN 0021-9193 Leelaram, Majety Naga ; Bhat, Anuradha Gopal ; Hegde, Shivanand Manjunath ; Manjunath, Ramanathapuram ; Nagaraja, Valakunja (2012) Inhibition of type IA topoisomerase by a monoclonal antibody through perturbation of DNA cleavage-religation equilibrium FEBS Journal, 279 (1). pp. 55-65. ISSN 1742-464X Kumar, R. ; Riley, J. E. ; Parry, D. ; Bates, A. D. ; Nagaraja, V. (2012) Binding of two DNA molecules by type II topoisomerases for decatenation Nucleic Acids Research, 40 (21). pp. 10904-10915. ISSN 0305-1048 Nagamalleswari, Easa ; Vasu, Kommireddy ; Nagaraja, Valakunja (2012) Ca2+ binding to the ExDxD motif regulates the DNA cleavage specificity of a promiscuous endonuclease Biochemistry, 51 (44). pp. 8939-8949. ISSN 0006-2960 Tare, Priyanka ; China, Arnab ; Nagaraja, Valakunja (2012) Distinct and contrasting transcription initiation patterns at Mycobacterium tuberculosis promoters PLoS One, 7 (9). Article ID e43900, 12 pages. ISSN 1932-6203 Vasu, K. ; Nagamalleswari, E. ; Nagaraja, V. (2012) Promiscuous restriction is a cellular defense strategy that confers fitness advantage to bacteria Proceedings of the National Academy of Sciences of the United States of America, 109 (20). E1287-E1293. ISSN 0027-8424 Karambelkar, S. ; Swapna, G. ; Nagaraja, V. (2012) Silencing of toxic gene expression by Fis Nucleic Acids Research, 40 (10). pp. 4358-4367. ISSN 0305-1048 Vasu, Kommireddy ; Saravanan, Matheshwaran ; Nagaraja, Valakunja (2011) Endonuclease active site plasticity allows DNA cleavage with diverse alkaline earth and transition metal ions ACS Chemical Biology, 6 (9). pp. 934-942. ISSN 1554-8929 Swapna, Ganduri ; Chakraborty, Atanu ; Kumari, Vandana ; Sen, Ranjan ; Nagaraja, Valakunja (2011) Mutations in β′ subunit of Escherichia coli RNA polymerase perturb the activator polymerase functional interaction required for promoter clearance Molecular Microbiology, 80 (5). pp. 1169-1185. ISSN 0950-382X Prabha, Swayam ; Rao, Desirazu N. ; Nagaraja, Valakunja (2011) Distinct properties of hexameric but functionally conserved Mycobacterium tuberculosis transcription-repair coupling factor PLoS One, 6 (4). Article ID e19131, 15 pages. ISSN 1932-6203 China, Arnab ; Mishra, Sonakshi ; Nagaraja, Valakunja (2011) A transcript cleavage factor of Mycobacterium tuberculosis important for its survival PLoS One, 6 (7). Article ID e21941, 13 pages. ISSN 1932-6203 Vasu, Kommireddy ; Saravanan, Matheshwaran ; Rajendra, Boggavarapu V. R. N. ; Nagaraja, Valakunja (2010) Generation of a manganese specific restriction endonuclease with nicking activity Biochemistry, 49 (38). pp. 8425-8433. ISSN 0006-2960 Anandhakumar, S. ; Nagaraja, V. ; Raichur, Ashok M. (2010) Reversible polyelectrolyte capsules as carriers for protein delivery Colloids and Surfaces B: Biointerfaces, 78 (2). pp. 266-274. ISSN 0927-7765 Leelaram, Majety Naga ; Suneetha, Nunna ; Nagaraja, Valakunja ; Manjunath, Ramanathapuram (2010) A new ELISA plate based microtiter well assay for mycobacterial topoisomerase I for the direct screening of enzyme inhibitory monoclonal antibody supernatants Journal of Immunological Methods, 357 (1-2). pp. 26-32. ISSN 0022-1759 Malshetty, Vidyasagar ; Kurthkoti, Krishna ; China, Arnab ; Mallick, Bratati ; Yamunadevi, Subburaj ; Sang, Pau Biak ; Srinivasan, Narayanaswamy ; Nagaraja, Valakunja ; Varshney, Umesh (2010) Novel insertion and deletion mutants of RpoB that render mycobacterium smegmatis RNA polymerase resistant to rifampicin-mediated inhibition of transcription Microbiology, 156 (5). pp. 1565-1573. ISSN 1350-0872 China, Arnab ; Nagaraja, Valakunja (2010) Purification of RNA polymerase from mycobacteria for optimized promoter-polymerase interactions Protein Expression and Purification, 69 (2). pp. 235-242. ISSN 1046-5928 China, Arnab ; Tare, Priyanka ; Nagaraja, Valakunja (2010) Comparison of promoter specific events during transcription initiation in mycobacteria Microbiology, 156 (7). pp. 1942-1952. ISSN 1350-0872 Mitra, Anirban ; Kesarwani, Anil K. ; Pal, Debnath ; Nagaraja, Valakunja (2010) WebGeSTer DB-a transcription terminator database Nucleic Acids Research . ISSN 0305-1048 Bhat, Anuradha Gopal ; Leelaram, Majety Naga ; Hegde, Shivanand Manjunath ; Nagaraja, Valakunja (2009) Deciphering the distinct role for the metal coordination motif in the catalytic activity of Mycobacterium smegmatis topoisomerase I Journal of Molecular Biology, 3934 (4). pp. 788-802. ISSN 0022-2836 Anil Kumar, K. N. ; Basu Ray, S. ; Nagaraja, V. ; Raichur, Ashok M. (2009) Encapsulation and release of rifampicin using poly(vinyl pyrrolidone)-poly(methacrylic acid) polyelectrolyte capsules Materials Science and Engineering: C - Biomimetic and Supramolecular Systems, 29 (8). pp. 2508-2513. ISSN 0928-4931 Williams, Diana L. ; Slayden, Richard A. ; Amin, Amol ; Martinez, Alejandra N. ; Pittman, Tana L. ; Mira, Alex ; Mitra, Anirban ; Nagaraja, Valakunja ; Morrison, Norman E. ; Moraes, Milton ; Gillis, Thomas P. (2009) Implications of high level pseudogene transcription in Mycobacterium leprae BMC Genomics, 10 (397). No pp. given. ISSN 1471-2164 Mitra, Anirban ; Angamuthu, Kandavelmani ; Jayashree, Hanasoge Vasudevamurthy ; Nagaraja, Valakunja (2009) Occurrence, divergence and evolution of intrinsic terminators across Eubacteria Genomics, 94 (2). pp. 110-116. ISSN 0888-7543 Leelaram, Majety Naga ; Bhat, Anuradha Gopal ; Suneetha, Nunna ; Nagaraja, Valakunja ; Manjunath, Ramanathapuram (2009) Immunological cross-reactivity of mycobacterial topoisomerase I and divergence from other bacteria Tuberculosis, 89 (4). pp. 256-262. ISSN 1472-9792 Swapna, Ganduri ; Saravanan, Matheswaran ; Nagaraja, Valakunja (2009) Conformational changes triggered by Mg2+ mediate transactivator function Biochemistry, 48 (11). pp. 2347-2354. ISSN 0006-2960 Senthilkumar, Palaniappan ; Dinakaran, Murugesan ; Yogeeswari, Perumal ; China, Arnab ; Nagaraja, V. ; Sriram, Dharmarajan (2009) Antimycobacterial activities of novel fluoroquinolones Biomedicine & Pharmacotherapy, 63 (1). pp. 27-35. ISSN 0753-3322 Senthilkumar, Palaniappan ; Dinakaran, Murugesan ; Yogeeswari, Perumal ; Sriram, Dharmarajan ; China, Arnab ; Nagaraja, Valakunja (2009) Synthesis and antimycobacterial activities of novel 6-nitroquinolone-3-carboxylic acids European Journal of Medicinal Chemistry, 44 (1). pp. 345-358. ISSN 0223-5234 Mitra, A. ; Angamuthu, K. ; Nagaraja, V. (2008) Genome-wide analysis of the intrinsic terminators of transcription across the genus Mycobacterium Tuberculosis, 88 (6). pp. 566-575. ISSN 1472-9792 Dinakaran, Murugesan ; Senthilkumar, Palaniappan ; Yogeeswari, Perumal ; China, Arnab ; Nagaraja, Valakunja ; Sriram, Dharmarajan (2008) Synthesis, antimycobacterial activities and phototoxic evaluation of 5H-thiazolo[3,2-a]quinoline-4-carboxylic acid derivatives Medicinal Chemistry, 4 (5). pp. 482-491. ISSN 1573-4064 Saravanan, Matheshwaran ; Vasu, Kommireddy ; Nagaraja, Valakunja (2008) Evolution of sequence specificity in a restriction endonuclease by a point mutation Proceedings of the National Academy of Sciences of the United States of America, 105 (30). pp. 10344-10347. ISSN 0027-8424 Murugesan, Dinakaran ; Palaniappan, Senthilkumar ; Perumal, Yogeeswari ; Arnab, China ; Valakunja, Nagaraja ; Sriram, Dharmarajan (2008) Antimycobacterial and phototoxic evaluation of novel 6-fluoro/nitro-4-oxo-7-(sub)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid International Journal of Antimicrobial Agents, 31 (4). pp. 337-344. ISSN 0924-8579 Dinakaran, Murugesan ; Senthilkumar, Palaniappan ; Yogeeswari, Perumal ; China, Arnab ; Nagaraja, Valakunja ; Sriram, Dharmarajan (2008) Antimycobacterial activities of novel 2-(sub)-3-fluoro/nitro-5,12-dihydro-5-oxobenzothiazolo[3,2-a]quinoline-6-carboxylic acid Bioorganic & Medicinal Chemistry, 16 (6). pp. 3408-3418. ISSN 0968-0896 Senthilkumar, Palaniappan ; Dinakaran, Murugesan ; Banerjee, Debjani ; Devakaram, Ruth Vandana ; Yogeeswari, Perumal ; China, Arnab ; Nagaraja, Valakunja ; Sriram, Dharmarajan (2008) Synthesis and antimycobacterial evaluation of newer 1-cyclopropyl-1,4-dihydro-6-fluoro-7-(substituted secondary amino)-8-methoxy-5-(sub)-4-oxoquinoline-3-carboxylic acids Bioorganic & Medicinal Chemistry, 16 (5). pp. 2558-2569. ISSN 0968-0896 Dinakaran, Murugesan ; Senthilkumar, Palaniappan ; Yogeeswari, Perumal ; China, Arnab ; Nagaraja, Valakunja ; Sriram, Dharmarajan (2008) Novel ofloxacin derivatives: synthesis, antimycobacterial and toxicological evaluation Bioorganic & Medicinal Chemistry Letters, 18 (3). pp. 1229-1236. ISSN 0960-894X Sengupta, Sugopa ; Nagaraja, Valakunja (2008) Inhibition of DNA gyrase activity by Mycobacterium smegmatis MurI FEMS Microbiology Letters, 279 (1). pp. 40-47. ISSN 0378-1097 Vasu, Kommireddy ; Saravanan, Matheshwaran ; Bujnicki, Janusz M. ; Nagaraja, Valakunja (2008) Structural integrity of the Beta Beta Alpha-Metal finger motif is required for DNA binding and stable protein-DNA complex formation in R.KpnI Biochimica et Biophysica Acta: Proteins & Proteomics, 1784 (2). pp. 269-275. ISSN 1570-9639 Sengupta, Sugopa ; Ghosh, Soumitra ; Nagaraja, Valakunja (2008) Moonlighting function of glutamate racemase from Mycobacterium tuberculosis: racemization and DNA gyrase inhibition are two independent activities of the enzyme Microbiology, 154 (9). pp. 2796-2803. ISSN 1350-0872 Sengupta, Sugopa ; Nagaraja, Valakunja (2008) YacG from Escherichia coli is a specific endogenous inhibitor of DNA gyrase Nucleic Acids Research, 36 (13). pp. 4310-4316. ISSN 0305-1048 Kamal, Ahmed ; Ahmed, S. K. ; Reddy, K. S. ; Khan, M. N. ; Shetty, Rajesh V. C. R. N. C. ; Siddhardha, B. ; Murty, U. S. N. ; China, A. ; Nagaraja, V. (2007) Synthesis and biological evaluation of a new series of benzothiazole-benzothiadiazine conjugates as antibacterial agents Letters in Drug Design and Discovery, 4 (8). pp. 550-556. ISSN 1570-1808 Sriram, Dharmarajan ; Senthilkumar, Palaniappan ; Dinakaran, Murugesan ; Yogeeswari, Perumal ; China, Arnab ; Nagaraja, Valakunja (2007) Antimycobacterial activities of novel 1-(cyclopropyl/tert-butyl/4-fluorophenyl)-1,4-dihydro- 6-nitro-4-oxo-7-(substituted secondary amino)-1,8-naphthyridine-3-carboxylic acid Journal of Medicinal Chemistry, 50 (24). pp. 6232-6239. ISSN 0022-2623 Saravanan, Matheshwaran ; Vasu, Kommireddy ; Ghosh, Soumitra ; Nagaraja, Valakunja (2007) Dual role for Zn2+ in maintaining structural integrity and inducing DNA sequence specificity in a promiscuous endonuclease Journal of Biological Chemistry, 282 (44). pp. 32320-32326. ISSN 0021-9258 Chakraborty, Atanu ; Paul, Bindu Diana ; Nagaraja, Valakunja (2007) Bacteriophage Mu C protein is a new member of unusual leucine zipper-HTH class of proteins Protein Engineering Design & Selection, 20 (1). pp. 1-5. ISSN 1741-0126 Dasgupta, Suryasarathi ; Navarrete, Ana-Maria ; Delignat, Sandrine ; Wootla, Bharath ; Andre, Sebastien ; Nagaraja, Valakunja ; Lacroix-Desmazes, Sebastien ; Kaveri, Srinivas V. (2007) Immune response against therapeutic factor VIII in hemophilia A patients-a survey of probable risk factors Immunology Letters, 110 (1). pp. 23-28. ISSN 0165-2478 Saravanan, Matheshwaran ; Vasu, Kommireddy ; Kanakaraj, Radhakrishnan ; Rao, Desirazu Narasimha ; Nagaraja, Valakunja (2007) R.KpnI, an HNH superfamily REase, exhibits differential discrimination at non-canonical sequences in the presence of Ca2+ and Mg2+ Nucleic Acids Research, 35 (8). pp. 2777-2786. ISSN 0305-1048 Lacroix-Desmazes, Sebastien ; Wootla, Bharath ; Dasgupta, Suryasarathi ; Delignat, Sandrine ; Bayry, Jagadeesh ; Reinbolt, Joseph ; Hoebeke, Johan ; Saenko, Evgueni ; Kazatchkine, Michel D. ; Friboulet, Alain ; Christophe, Olivier ; Nagaraja, Valakunja ; Kaveri, Srini V. (2006) Catalytic IgG from patients with hemophilia A inactivate therapeutic factor VIII Journal of Immunology, 177 (2). pp. 1355-1363. ISSN 0022-1767 Wootla, Bharath ; Dasgupta, Suryasarathi ; Mallet, Vincent ; Kazatchkine, Michel D. ; Nagaraja, Valakunja ; Friboulet, Alain ; Kaveri, Srinivas V. ; Lacroix-Desmazes, Sebastien (2006) Physiopathology of catalytic antibodies: the case for factor VIII-hydrolyzing immunoglobulin G Blood Coagulation and Fibrinolysis, 17 (4). pp. 229-234. ISSN 0957-5235 Gupta, Richa ; China, Arnab ; Manjunatha, Ujjini H. ; Ponnanna, N. M. ; Nagaraja, Valakunja (2006) A complex of DNA gyrase and RNA polymerase fosters transcription in Mycobacterium smegmatis Biochemical and Biophysical Research Communications, 343 (4). pp. 1141-1145. ISSN 0006-291X Bheemanaik, Shivakumara ; Bujnicki, Janusz M. ; Nagaraja, Valakunja ; Rao, Desirazu N. (2006) Functional analysis of amino acid residues at the dimerisation interface of KpnI DNA methyltransferase Biological Chemistry, 387 (5). pp. 515-523. ISSN 1431-6730 Jain, Paras ; Nagaraja, Valakunja (2006) Indispensable, functionally complementing N and C-terminal domains constitute site-specific topoisomerase I Journal of Molecular Biology, 357 (5). pp. 1409-1421. ISSN 0022-2836 Chakraborty, Atanu ; Nagaraja, Valakunja (2006) Dual role for transactivator protein C in activation of mom promoter of bacteriophage Mu Journal of Biological Chemistry, 281 (13). pp. 8511-8517. ISSN 0021-9258 Lacroix-Desmazes, Sebastien ; Wootla, Bharath ; Delignat, Sandrine ; Dasgupta, Suryasarathi ; Nagaraja, Valakunja ; Kazatchkine, Michel D. ; Kaveri, Srini V. (2006) Pathophysiology of catalytic antibodies Immunology Letters, 103 (1). pp. 3-7. ISSN 0165-2478 Sriram, Dharmarajan ; Bal, Tanushree Ratan ; Yogeeswari, Perumal ; Radha, Deshpande R. ; Nagaraja, Valakunja (2006) Evaluation of antimycobacterial and DNA gyrase inhibition of fluoroquinolone derivatives Journal of General and Applied Microbiology, 52 (4). pp. 195-200. ISSN 0022-1260 Sengupta, Sugopa ; Shah, Meera ; Nagaraja, Valakunja (2006) Glutamate racemase from Mycobacterium tuberculosis inhibits DNA gyrase by affecting its DNA-binding Nucleic Acids Research, 34 (19). pp. 5567-5576. ISSN 0305-1048 Jain, Paras ; Nagaraja, Valakunja (2005) An atypical type II topoisomerase from Mycobacterium smegmatis with positive supercoiling activity Molecular Microbiology, 58 (5). pp. 1392-1405. ISSN 0950-382X Sriram, Dharmarajan ; Yogeeswari, Perumal ; Basha, Jafar Sadik ; Radha, Deshpande R. ; Nagaraja, Valakunja (2005) Synthesis and antimycobacterial evaluation of various 7-substituted ciprofloxacin derivatives Bioorganic & Medicinal Chemistry, 13 (20). pp. 5774-5778. ISSN 0968-0896 Lacroix-Desmazes, Sebastien ; Bayry, Jagadeesh ; Kaveri, Srini V. ; Hayon-Sonsino, David ; Thorenoor, Nithyananda ; Charpentier, Julien ; Luyt, Charles-Edouard ; Mira, Jean-Paul ; Nagaraja, Valakunja ; Kazatchkine, Michel D. ; Dhainaut, Jean-Francois ; Mallet, Vincent O. (2005) High levels of catalytic antibodies correlate with favorable outcome in sepsis Proceedings of the National Academy of Sciences of the United States of America, 102 (11). pp. 4109-4113. ISSN 0027-8424 Manjunatha, Ujjini H. ; Maxwell, Anthony ; Nagaraja, Valakunja (2005) A monoclonal antibody that inhibits mycobacterial DNA gyrase by a novel mechanism Nucleic Acids Research, 33 (10). pp. 3085-3094. ISSN 0305-1048 Chandrashekaran, Siddamadappa ; Saravanan, Matheshwaran ; Radha, Deshpande R. ; Nagaraja, Valakunja (2004) Ca2+-mediated site-specific DNA cleavage and suppression of promiscuous activity of KpnI restriction endonuclease Journal of Biological Chemistry, 279 (48). pp. 49736-49740. ISSN 0021-9258 Nagaraja, V. (2004) Regulation of DNA topology in mycobacteria Current Science, 86 (1). pp. 135-140. ISSN 0011-3891 Chandrashekaran, Siddamadappa ; Manjunatha, U. H. ; Nagaraja, Valakunja (2004) KpnI restriction endonuclease and methyltransferase exhibit contrasting mode of sequence recognition Nucleic Acids Research, 32 (10). pp. 3148-3155. ISSN 0305-1048 Saravanan, Matheshwaran ; Bujnicki, Janusz M. ; Cymerman, Iwona A. ; Rao, Desirazu Narasimha ; Nagaraja, Valakunja (2004) Type II restriction endonuclease R.KpnI is a member of the HNH nuclease superfamily Nucleic Acids Research, 32 (20). pp. 6129-6135. ISSN 0305-1048 Paul, Bindu Diana ; Kanhere, Aditi ; Chakraborty, Atanu ; Bansal, Manju ; Nagaraja, Valakunja (2003) Identification of the domains for DNA binding and transactivation function of C protein from bacteriophage Mu Proteins: Structure, Function, and Bioinformatics, 52 (2). pp. 272-282. ISSN 0887-3585 Saravanan, Matheshwaran ; Elango, Kathirvel ; Chandrashekaran, Siddamadappa ; Anand, Narayanaswamy ; Nagaraja, Valakunja (2003) A new type II restriction endonuclease, OfoI from nonheterocystous cyanobacterium Oscillatoria foreaui Current Science, 85 (2). pp. 188-191. ISSN 0011-3891 Bheemanaik, Shivakumar ; Chandrashekaran, Siddamadappa ; Nagaraja, Valakunja ; Rao, Desirazu Narasimha (2003) Kinetic and catalytic properties of dimeric KpnI DNA methyltransferase Journal of Biological Chemistry, 278 (10). pp. 7863-7874. ISSN 0021-9258 Chatterji, Monalisa ; Sengupta, Sugopa ; Nagaraja, Valakunja (2003) Chromosomally encoded gyrase inhibitor GyrI protects Escherichia coli against DNA-damaging agents Archives of Microbiology, 180 (5). pp. 339-346. ISSN 0302-8933 Roberts, Richard J. ; Belfort, Marlene ; Bestor, Timothy ; Bhagwat, Ashok S. ; Bickle, Thomas A. ; Bitinaite, Jurate ; Blumentha, Robert M. ; Degtyarev, Sergey Kh. ; Dryden, David T. F. ; Dybvig, Kevin ; Firman, Keith ; Gromova, Elizaveta S. ; Gumport, Richard I. ; Halford, Stephen E. ; Hattman, Stanley ; Heitman, Joseph ; Hornby, David P. ; Janulaitis, Arvydas ; Jeltsch, Albert ; Josephsen, Jytte ; Kiss, Antal ; Klaenhammer, Todd R. ; Kobayashi, Ichizo ; Kong, Huimin ; Kruger, Detlev H. ; Lacks, Sanford ; Marinus, Martin G. ; Miyahara, Michiko ; Morgan, Richard D. ; Murray, Noreen E. ; Nagaraja, Valakunja ; Piekarowicz, Andrzej ; Pingoud, Alfred ; Raleigh, Elisabeth ; Rao, Desirazu N. ; Reich, Norbert ; Repin, Vladimir E. ; Selker, Eric U. ; Shaw, Pang-Chui ; Stein, Daniel C. ; Stoddard, Barry L. ; Szybalski, Waclaw ; Trautner, Thomas A. ; Van Etten, James L. ; Vitor, Jorge M. B. ; Wilson, Geoffrey G. ; Xu, Shuang-yong (2003) A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes Nucleic Acids Research, 31 (7). pp. 1805-1812. ISSN 0305-1048 Jain, P. ; Nagaraja, V. (2002) An orphangyr B in the Mycobacterium smegmatis genome uncovered by comparative genomics Journal of Genetics, 81 (3). pp. 105-110. ISSN 0022-1333 Unniraman, Shyam ; Chatterji, Monalisa ; Nagaraja, Valakunja (2002) DNA gyrase genes in mycobacterium tuberculosis: a single operon driven by multiple promoters Journal of Bacteriology, 184 (19). pp. 5449-5456. ISSN 0021-9193 Kalate, Rupali N. ; Kulkarni, B. D. ; Nagaraja, V. (2002) Analysis of DNA curvature distribution in mycobacterial promoters using theoretical models Biophysical Chemistry, 99 (1). pp. 77-97. ISSN 0301-4622 Unniraman, Shyam ; Prakash, Ranjana ; Nagaraja, Valakunja (2002) Conserved economics of transcription termination in eubacteria Nucleic Acids Research, 30 (3). pp. 675-684. ISSN 0305-1048 Manjunatha, U. H. ; Dalal, M. ; Chatterji, M. ; Radha, D. R. ; Visweswariah, S. S. ; Nagaraja, V. (2002) Functional characterisation of mycobacterial DNA gyrase: an efficient decatenase Nucleic Acids Research, 30 (10). pp. 2144-2153. ISSN 0305-1048 Chatterji, Monalisa ; Nagaraja, Valakunja (2002) GyrI: a counter-defensive strategy against proteinaceous inhibitors of DNA gyrase EMBO reports, 3 (3). pp. 261-267. ISSN 1469-221X Unniraman, Shyam ; Chatterji, Monalisa ; Nagaraja, Valakunja (2002) A hairpin near the 5' end stabilises the DNA gyrase mRNA in Mycobacterium smegmatis Nucleic Acids Research, 30 (24). pp. 5376-5381. ISSN 0305-1048 Basak, Shashwati ; Nagaraja, Valakunja (2001) DNA unwinding mechanism for the transcriptional activation of momP1 promoter by the transactivator protein C of bacteriophage Mu Journal of Biological Chemistry, 276 (50). pp. 46941-46945. ISSN 0021-9258 Unniraman, Shyam ; Nagaraja, Valakunja (2001) Axial distortion as a sensor of supercoil changes: a molecular model for the homeostatic regulation of DNA gyrase Journal of Genetics, 80 (3). pp. 119-124. ISSN 0022-1333 Unniraman, Shyam ; Prakash, Ranjana ; Nagaraja, Valakunja (2001) Alternate paradigm for intrinsic transcription termination in eubacteria Journal of Biological Chemistry, 276 (45). pp. 41850-41855. ISSN 0021-9258 Sikder, Devanjan ; Nagaraja, Valakunja (2001) A novel bipartite mode of binding of M. smegmatis topoisomerase I to its recognition sequence Journal of Molecular Biology, 312 (2). pp. 347-357. ISSN 0022-2836 Basak, Shashwati ; Olsen, Lars ; Hattman, Stanley ; Nagaraja, Valakunja (2001) Intrinsic DNA distortion of the bacteriophage MumomP1 promoter is a negative regulator of its transcription: a novel mode of regulation of toxic gene expression Journal of Biological Chemistry, 276 (23). pp. 19836-19844. ISSN 0021-9258 Manjunatha, U. H. ; Mahadevan, S. ; Visweswariah, Sandhya S. ; Nagaraja, V. (2001) Monoclonal antibodies to mycobacterial DNA gyrase A inhibit DNA supercoiling activity European Journal of Biochemistry, 268 (7). pp. 2038-2046. ISSN 0014-2956 Sikder, Devanjan ; Unniraman, Shyam ; Bhaduri, Tisha ; Nagaraja, Valakunja (2001) Functional cooperation between topoisomerase I and single strand DNA-binding protein Journal of Molecular Biology, 306 (4). pp. 669-679. ISSN 0022-2836 Manjunatha, U. H. ; Somesh, B. P. ; Nagaraja, V. ; Visweswariah, S. S. (2001) A Mycobacterium smegmatis gyrase B specific monoclonal antibody reveals association of gyrase A and B subunits in the cell FEMS Microbiology Letters, 194 (1). pp. 87-92. ISSN 0378-1097 Chatterji, Monalisa ; Unniraman, Shyam ; Mahadevan, Sethuraman ; Nagaraja, Valakunja (2001) Effect of different classes of inhibitors on DNA gyrase from Mycobacterium smegmatis Journal of Antimicrobial Chemotherapy, 48 (4). pp. 479-485. ISSN 0305-7453 Basak, Shashwati ; Nagaraja, V. (2001) A versatile in vivo footprinting technique using 1,10-phenanthroline-copper complex to study important cellular processes Nucleic Acids Research, 29 (21). e105_1-e105_6. ISSN 0305-1048 Bhaduri, Tisha ; Basak, Shashwati ; Sikder, Devanjan ; Nagaraja, V. (2000) Inhibition of Mycobacterium smegmatis topoisomerase I by specific oligonucleotides FEBS Letters, 486 (2). pp. 126-130. ISSN 0014-5793 Manjunatha, U. H. ; Madhusudan, K. ; Visweswariah, S. S. ; Nagaraja, V. (2000) Structural heterogeneity in DNA gyrases from Gram-positive and Gram-negative bacteria Current Science, 79 (7). pp. 968-974. ISSN 0011-3891 Chatterji, Monalisa ; Unniraman, Shyam ; Maxwell, Anthony ; Nagaraja, Valakunja (2000) The additional 165 amino acids in the B protein of Escherichia coli DNA gyrase have an important role in DNA binding Journal of Biological Chemistry, 275 (30). pp. 22888-22894. ISSN 0021-9258 Sikder, Devanjan ; Nagaraja, Valakunja (2000) Determination of the recognition sequence of Mycobacterium smegmatis topoisomerase I on mycobacterial genomic sequences Nucleic Acids Research, 28 (8). pp. 1830-1837. ISSN 0305-1048 Unniraman, Shyam ; Nagaraja, Valakunja (1999) Regulation of DNA gyrase operon in Mycobacterium smegmatis: a distinct mechanism of relaxation stimulated transcription Genes to Cells, 4 (12). pp. 697-706. ISSN 1356-9597 Chandrashekaran, Siddamadappa ; Babu, Padmanabhan ; Nagaraja, Valakunja (1999) Characterization of DNA binding activities of over-expressed KpnI restriction endonuclease and modification methylase Journal of Biosciences, 24 (3). pp. 269-277. ISSN 0250-5991 Chandrashekaran, Siddamadappa ; Shankar, Aparna Bhavani ; Babu, Padmanabhan ; Paul, Bindu Diana ; Nagaraja, Valakunja (1999) Identification and characterization of a type II restriction endonuclease, Str1 from Streptomyces thermodiastaticus Current Science, 77 (2). pp. 273-276. ISSN 0011-3891 Janscak, Pavel ; MacWilliams, Maria P. ; Sandmeier, Ursula ; Nagaraja, Valakunja ; Bickle, Thomas A. (1999) DNA translocation blockage, a general mechanism of cleavage site selection by type I restriction enzymes EMBO Journal, 18 (9). pp. 2638-2647. ISSN 0261-4189 Chandrashekaran, Siddamadappa ; Babu, Padmanabhan ; Nagaraja, Valakunja (1999) Purification and characterization of restriction endonuclease BasI from Bacillus species The Journal of Biochemistry, Molecular Biology and Biophysics, 3 . pp. 225-229. ISSN 1025-8140 Basak, Shashwati ; Nagaraja, Valakunja (1998) Transcriptional activator C protein-mediated unwinding of DNA as a possible mechanism for mom gene activation Journal of Molecular Biology, 284 (4). pp. 893-902. ISSN 0022-2836 Bhaduri, Tisha ; Bagui, Tapan Kumar ; Sikder, Devanjan ; Nagaraja, Valakunja (1998) DNA topoisomerase I from Mycobacterium smegmatis: an enzyme with distinct features Journal of Biological Chemistry, 273 (22). pp. 13925-13932. ISSN 0021-9258 Chandrashekharan, Siddamadappa ; Paul, Bindu Diana ; Nagaraja, Valakunja (1998) Design of a novel regulatory circuit for expression of restriction endonucleases Biological Chemistry, 379 . pp. 579-582. ISSN 1431-6730 De, Amitabha ; Ramesh, V. ; Mahadevan, S. ; Nagaraja, V. (1998) Mg2+ mediated sequence-specific binding of transcriptional activator protein C of bacteriophage Mu to DNA Biochemistry, 37 (11). pp. 3831-3838. ISSN 0006-2960 Bhaduri, Tisha ; Sikder, Devanjan ; Nagaraja, Valakunja (1998) Sequence specific interaction of Mycobacterium smegmatis topoisomerase I with duplex DNA Nucleic Acids Research, 26 (7). pp. 1668-1674. ISSN 0305-1048 De, A. ; Paul, B. D. ; Ramesh, V. ; Nagaraja, V. (1997) Use of protein A gene fusions for the analysis of structure-function relationship of the transactivator protein C of bacteriophage Mu Protein Engineering Design & Selection, 10 (8). pp. 935-941. ISSN 1741-0126 Paul, Bindu D. ; Ramesh, Vaidyanathan ; Nagaraja, Valakunja (1997) An artificial regulatory circuit for stable expression of DNA-binding proteins in a T7 expression system Gene, 190 (1). pp. 11-15. ISSN 0378-1119 Madhusudan, K. ; Nagaraja, V. (1996) Alignment and phylogenetic analysis of type II DNA topoisomerases Journal of Biosciences, 21 (5). pp. 613-629. ISSN 0250-5991 Ramesh, V. ; Nagaraja, V. (1996) Sequence-specific DNA binding of the phage Mu C protein: footprinting analysis reveals altered DNA conformation upon protein binding Journal of Molecular Biology, 260 (1). pp. 22-23. ISSN 0022-2836 Nair, T. Murlidharan ; Madhusudan, K. ; Nagaraja, V. ; Kulkarni, B. D. ; Majumdar, H. K. ; Singh, Rajan (1996) Theoretical permutation gel electrophoretic analysis of a curved DNA fragment located in circular permutation Electrophoresis, 17 (4). pp. 633-641. ISSN 0173-0835 Madhusudan, K. ; Nagaraja, V. (1995) Mycobacterium smegmatis DNA gyrase: cloning and overexpression in Escherichia coli Microbiology, 141 (12). pp. 3029-3037. ISSN 1350-0872 Hemavathy, Kirugaval C. ; Nagaraja, Valakunja (1995) DNA methylation in mycobacteria: absence of methylation at GATC (Dam) and CCA/TGG (Dcm) sequences FEMS Immunology and Medical Microbiology, 11 (4). pp. 291-296. ISSN 0928-8244 Nair, T. Murlidharan ; Kulkarni, B. D. ; Nagaraja, V. (1995) Differential binding of RNA polymerase to the wild type Mu mom promoter and its C independent mutant: a theoretical analysis Biophysical Chemistry, 53 (3). pp. 241-245. ISSN 0301-4622 Nair, T. Murlidharan ; Madhusudan, K. ; Nagaraja, V. ; Kulkarni, B. D. ; Majumdar, H. K. ; Singh, Rajan (1994) On the mobility behavior of a curved DNA fragment located in circular permutations FEBS Letters, 351 (3). pp. 321-324. ISSN 0014-5793 Ramesh, V. ; De, A. ; Nagaraja, V. (1994) Overproduction and purification of C protein, the late gene transcription activator from phage Mu Protein Expression and Purification, 5 (4). pp. 379-384. ISSN 1046-5928 Madhusudan, K. ; Ramesh, V. ; Nagaraja, V. (1994) Molecular cloningof gyrA and gyrB genes from Mycobacterium tuberculosis: analysis of Nucleotide sequence Biochemistry and Molecular Biology International, 33 (4). pp. 651-660. ISSN 1039-9712 Madhusudan, K. ; Ramesh, V. ; Nagaraja, V. (1994) Cloning and sequence analysis of DNA gyrase genes from Mycobacterium tuberculosis Current Science, 66 (9). pp. 664-667. ISSN 0011-3891 Ramesh, V. ; De, Amitabha ; Nagaraja, V. (1994) Engineering hyperexpression of bacteriophage Mu C protein by removal of secondary structure at the translation initiation region Protein Engineering Design & Selection, 7 (8). pp. 1053-1057. ISSN 1741-0126 Said Ahmed, M. ; Ramesh, V. ; Nagaraja, V. ; Parish, J. H. ; Hadi, S. M. (1994) Mode of binding of quercetin to DNA Mutagenesis, 9 (3). pp. 193-197. ISSN 0267-8357 Nagaraja, V. (1993) Control of transcription initiation Journal of Biosciences, 18 (1). pp. 13-25. ISSN 0250-5991 Balke, Virginia ; Nagaraja, Valakunja ; Gindlesperger, Tracy ; Hattman, Stanley (1992) Functionally distinct RNA polymerase binding sites in the phage Mu mom promoter region Nucleic Acids Research, 20 (11). pp. 2777-2784. ISSN 0305-1048 Hattman, Stanley ; Newman, Laurel ; Krishna Murthy, H. M. ; Nagaraja, V. (1991) Com, the phage Mu mom translational activator, is a zinc-binding protein that binds specifically to its cognate mRNA Proceedings of the National Academy of Sciences of the United States of America, 88 (22). pp. 10027-10031. ISSN 0027-8424 Nagaraja, Valakunja ; Hecht, Gregory ; Hattman, Stanley (1988) The phage Mu 'late' gene transcription activator, C, is a site-specific DNA binding protein Biochemical Pharmacology, 37 (9). pp. 1809-1810. ISSN 0006-2952 Nagaraja, V. ; Gopinathan, K. P. (1987) Transcriptional specificity after mycobacteriophage I3 infection Journal of Biosciences, 11 (1-4). pp. 167-179. ISSN 0250-5991 Nagaraja, Valakunja ; Shepherd, John C. W. ; Bickle, Thomas A. (1985) A hybrid recognition sequence in a recombinant restriction enzyme and the evolution of DNA sequence specificity Nature, 316 (6026). pp. 371-372. ISSN 0028-0836 Nagaraja, Valakunja ; Shepherd, John C. W. ; Pripfl, Therese ; Bickle, Thomas A. (1985) Two type I restriction enzymes from Salmonella species: purification and DNA recognition sequences Journal of Molecular Biology, 182 (4). pp. 579-587. ISSN 0022-2836 Nagaraja, Valakunja ; Stieger, Martin ; Nager, Christoph ; Hadi, Sheikh M. ; Bickle, Thomas A. (1985) The nucleotide sequence recognised by the Escherichia coli D type I restriction and modification enzyme Nucleic Acids Research, 13 (2). pp. 389-399. ISSN 0305-1048 Nagaraja, V. ; Gopinathan, K. P. (1981) Involvement of DNA gyrase in the replication and transcription of mycobacteriophage 13 DNA FEBS Letters, 127 (1). pp. 57-62. ISSN 0014-5793 Nagaraja, V. ; Gopinathan, K. P. (1981) Macromolecular synthesis in mycobacteriophage I3 infected cells Molecular Biology Reports, 8 (1). pp. 11-15. ISSN 0301-4851 Nagaraja, V. ; Gopinathan, K. P. (1980) Requirement for calcium ions in mycobacteriophage I3 DNA injection and propagation Archives of Microbiology, 124 (2-3). pp. 249-254. ISSN 0302-8933 |