Jain, P. ; Nagaraja, V. (2002) An orphangyr B in the Mycobacterium smegmatis genome uncovered by comparative genomics Journal of Genetics, 81 (3). pp. 105-110. ISSN 0022-1333
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Official URL: http://www.ias.ac.in/jgenet/Vol81No3/105.pdf
Related URL: http://dx.doi.org/10.1007/BF02715907
Abstract
DNA gyrase is an essential topoisomerase found in all bacteria. It is encoded by gyrB and gyrA genes. These genes are organized differently in different bacteria. Direct comparison of Mycobacterium tuberculosis and Mycobacterium smegmatis genomes reveals presence of an additionalgyr B in M. smegmatis flanked by novel genes. Analysis of the amino acid sequence of GyrB from different organisms suggests that the orphan GyrB in M. smegmatis may have an important cellular role.
| Item Type: | Article |
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| Source: | Copyright of this article belongs to Indian Academy of Sciences. |
| Keywords: | Mycobacterium Smegmatis; gyr Genes; DNA Gyrase; Topoisomerase; Comparative Genomics |
| ID Code: | 27006 |
| Deposited On: | 08 Dec 2010 12:52 |
| Last Modified: | 17 May 2016 10:18 |
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