Kamal, Ahmed ; Ahmed, S. K. ; Reddy, K. S. ; Khan, M. N. ; Shetty, Rajesh V. C. R. N. C. ; Siddhardha, B. ; Murty, U. S. N. ; China, A. ; Nagaraja, V. (2007) Synthesis and biological evaluation of a new series of benzothiazole-benzothiadiazine conjugates as antibacterial agents Letters in Drug Design and Discovery, 4 (8). pp. 550-556. ISSN 1570-1808
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Official URL: http://www.ingentaconnect.com/content/ben/lddd/200...
Related URL: http://dx.doi.org/10.2174/157018007782794563
Abstract
A new series of benzothiazolo-benzothiadiazine hybrids (9a-g) has been synthesized and evaluated for their antibacterial activity against clinical isolates of Gram-positive and Gram-negative bacteria. Some of these hybrids in this series exhibited antibacterial activity comparable to ampicillin. In addition, some of the compounds showed DNA gyrase inhibitory activity at a moderate level compared to ciprofloxacin.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Bentham Science Publishers. |
| Keywords: | Benzothiadiazines; Benzothiazoles; Antibacterial Activity; DNA Gyrase Inhibition |
| ID Code: | 89560 |
| Deposited On: | 28 Apr 2012 14:30 |
| Last Modified: | 28 Apr 2012 14:30 |
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