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Number of items: 105. Sebastian, Robin ; Raghavan, Sathees C. (2017) Molecular mechanism of Endosulfan action in mammals Journal of Biosciences, 42 (1). pp. 149-153. ISSN 0250-5991 Pandey, Monica ; Kumar, Sujeet ; Goldsmith, Gunaseelan ; Srivastava, Mrinal ; Elango, Santhini ; Shameem, Mohammad ; Bannerjee, Dibyendu ; Choudhary, Bibha ; Karki, Subhas S. ; Raghavan, Sathees C. (2017) Identification and characterization of novel ligase I inhibitors Molecular Carcinogenesis, 56 (2). pp. 550-566. ISSN 0899-1987 Ghoshal, Nitin ; Sharma, Sheetal ; Banerjee, Atanu ; Kurkalang, Sillarine ; Raghavan, Sathees C. ; Chatterjee, Anupam (2017) Influence of reduced glutathione on end-joining of DNA double-strand breaks: cytogenetical and molecular approach Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 795 . pp. 1-9. ISSN 0027-5107 Vartak, Supriya V. ; Hegde, Mahesh ; Iyer, Divyaanka ; Gaikwad, Snehal ; Gopalakrishnan, Vidya ; Srivastava, Mrinal ; Karki, Subhas S. ; Choudhary, Bibha ; Ray, Pritha ; Santhoshkumar, T. R. ; Raghavan, Sathees C. (2016) A novel inhibitor of BCL2, Disarib abrogates tumor growth while sparing platelets, by activating intrinsic pathway of apoptosis Biochemical Pharmacology, 122 . pp. 10-22. ISSN 0006-2952 Hegde, Mahesh ; Mantelingu, Kempegowda ; Pandey, Monica ; Pavankumar, Chottanahalli S. ; Rangappa, Kanchugarakoppal S. ; Raghavan, Sathees C. (2016) Combinatorial study of a novel poly (ADP-ribose) polymerase inhibitor and an HDAC inhibitor, SAHA, in leukemic cell lines Targeted Oncology, 11 (5). pp. 655-665. ISSN 1776-2596 Iyer, Divyaanka ; Vartak, Supriya V. ; Mishra, Archita ; Goldsmith, Gunaseelan ; Kumar, Sujeet ; Srivastava, Mrinal ; Hegde, Mahesh ; Gopalakrishnan, Vidya ; Glenn, Mark ; Velusamy, Mahesh ; Choudhary, Bibha ; Kalakonda, Nagesh ; Karki, Subhas S. ; Surolia, Avadhesha ; Raghav, Sathees C. (2016) Identification of a novel BCL2‐specific inhibitor that binds predominantly to the BH1 domain The FEBS Journal, 283 (18). pp. 3408-3437. ISSN 1742-464X Sebastian, Robin ; Raghavan, Sathees C. (2016) Induction of DNA damage and erroneous repair can explain genomic instability caused by endosulfan Carcinogenesis, 37 (10). pp. 929-940. ISSN 0143-3334 Das, Kohal ; Srivastava, Mrinal ; Raghavan, Sathees C. (2016) GNG motifs can replace a GGG stretch during G-quadruplex formation in a context dependent manner PLoS One, 11 (7). Article ID e0158794, 21 pages. ISSN 1932-6203 Tadi, Satish Kumar ; Sebastian, Robin ; Dahal, Sumedha ; Babu, Ravi K. ; Choudhary, Bibha ; Raghavan, Sathees C. (2016) Microhomology-mediated end joining is the principal mediator of double-strand break repair during mitochondrial DNA lesions Molecular Biology of the Cell, 27 (2). pp. 223-235. ISSN 1059-1524 Thomas, Elizabeth ; Gopalakrishnan, Vidya ; Somasagara, Ranganatha R. ; Choudhary, Bibha ; Raghavan, Sathees C. (2016) Extract of Vernonia condensata, inhibits tumor progression and improves survival of tumor-allograft bearing mouse Scientific Reports, 6 . Article ID 23255, 12 pages. ISSN 2045-2322 Hegde, Mahesh ; Mantelingu, Kempegowda ; Swarup, Hassan A. ; Pavankumar, Chottanahalli S. ; Qamar, Imteyaz ; Raghavan, Sathees C. ; Rangappa, Kanchugarakoppal S. (2016) Novel PARP inhibitors sensitize human leukemic cells in an endogenous PARP activity dependent manner RSC Advances, 6 (8). pp. 6308-6319. ISSN 2046-2069 Chiruvella, Kishore K. ; Nishana, Mayilaadumveettil ; Gopalakrishnan, Vidya ; Ranganatha, Somasagara R. ; Tadi, Satish Kumar ; Choudhary, Bibha ; Raghavan, Sathees C. (2016) Plant-derived tetranortriterpenoid, methyl angolensate activates apoptosis and prevents ehrlich ascites carcinoma induced tumorigenesis in mice British Journal of Medicine and Medical Research, 12 (11). pp. 1-10. ISSN 2231-0614 Srivastava, Shikha ; Somasagara, Ranganatha R. ; Hegde, Mahesh ; Nishana, Mayilaadumveettil ; Tadi, Satish Kumar ; Srivastava, Mrinal ; Choudhary, Bibha ; Raghavan, Sathees C. (2016) Quercetin, a natural flavonoid interacts with DNA, arrests cell cycle and causes tumor regression by activating mitochondrial pathway of apoptosis Scientific Reports, 6 . Article ID 24049, 13 pages. ISSN 2045-2322 Thomas, Elizabeth ; Gopalakrishnan, Vidya ; Hegde, Mahesh ; Kumar, Sujeet ; Karki, Subhas S. ; Raghavan, Sathees C. ; Choudhary, Bibha (2016) A novel resveratrol based tubulin inhibitor induces mitotic arrest and activates apoptosis in cancer cells Scientific Reports, 6 . Article ID 34653, 13 pages. ISSN 2045-2322 Sebastian, R. ; Raghavan, Sathees C. (2015) Exposure to endosulfan can result in male infertility due to testicular atrophy and reduced sperm count Cell Death Discovery, 1 . Article ID 15020, 10 pages. ISSN 2058-7716 Vartak, Supriya V. ; Raghavan, Sathees C. (2015) Inhibition of nonhomologous end joining to increase the specificity of CRISPR/Cas9 genome editing The FEBS Journal, 282 (22). pp. 4289-4294. ISSN 1742-464X Mohammed, Arifullah ; Chiruvella, Kishore K. ; Rao, Yerra Koteswara ; Geethangili, Madamanchi ; Raghavan, Sathees C. ; Ghanta, Rama Gopal (2015) In vitro production of echioidinin, 7-O-Methywogonin from callus cultures of Andrographis lineata and their cytotoxicity on cancer cells PLoS One, 10 (10). Article ID e0141154, 14 pages. ISSN 1932-6203 NaveenKumar, Somanathapura K. ; Thushara, Ram M. ; Sundaram, Mahalingam S. ; Hemshekhar, Mahadevappa ; Paul, Manoj ; Thirunavukkarasu, Chinnasamy ; Basappa, . ; Nagaraju, Ganesh ; Raghavan, Sathees C. ; Girish, Kesturu S. ; Kemparaju, Kempaiah ; Rangappa, Kanchugarakoppal S. (2015) Unconjugated bilirubin exerts pro-apoptotic effect on platelets via p38-MAPK activation Scientific Reports, 5 . Article ID 15045, 16 pages. ISSN 2045-2322 Sharath Kumar, Kothanahally S. ; Hanumappa, Ananda ; Vetrivel, Maruthai ; Hegde, Mahesh ; Girish, Yarabhally R. ; Byregowda, Thinnali R. ; Rao, Suguna ; Raghavan, Sathees C. ; Rangappa, Kanchugarakoppal S. (2015) Antiproliferative and tumor inhibitory studies of 2, 3 disubstituted 4-thiazolidinone derivatives Bioorganic & Medicinal Chemistry Letters, 25 (17). pp. 3616-3620. ISSN 0960-894X Javadekar, Saniya M. ; Raghavan, Sathees C. (2015) Snaps and mends: DNA breaks and chromosomal translocations The FEBS Journal, 282 (14). 2627 -2645. ISSN 1742-464X RohitKumar, Heggodu G. ; Asha, Kittur R. ; Raghavan, Sathees C. ; Advi Rao, Gopal M. (2015) DNA intercalative 4-butylaminopyrimido [4′, 5′: 4, 5] thieno (2, 3-b) quinoline induces cell cycle arrest and apoptosis in leukemia cells Cancer Chemotherapy and Pharmacology, 75 (6). pp. 1121-1133. ISSN 0344-5704 John, Franklin ; George, Jinu ; Vartak, Supriya V. ; Srivastava, Mrinal ; Hassan, P. A. ; Aswal, V. K. ; Karki, Subhas. S. ; Raghavan, Sathees C. (2015) Enhanced efficacy of pluronic copolymer micelle encapsulated SCR7 against cancer cell proliferation Macromolecular Bioscience, 15 (4). pp. 521-534. ISSN 1616-5187 Kumari, Rupa ; Nambiar, Mridula ; Shanbagh, Shaika ; Raghavan, Sathees C. (2015) Detection of G-quadruplex DNA using primer extension as a tool PLoS One, 10 (3). Article ID e0119722, 14 pages. ISSN 1932-6203 Sharma, S. ; Javadekar, S. M. ; Pandey, M. ; Srivastava, M. ; Kumari, R. ; Raghavan, S. C. (2015) Homology and enzymatic requirements of microhomology-dependent alternative end joining Cell Death and Disease, 6 . Article ID e1697, 12 pages. ISSN 2041-4889 Srivastava, Mrinal ; Raghavan, Sathees C. (2015) DNA double-strand break repair inhibitors as cancer therapeutics Chemistry & Biology, 22 (1). pp. 17-29. ISSN 1074-5521 Kumari, Rupa ; Raghavan, Sathees C. (2015) Structure‐specific nuclease activity of RAGs is modulated by sequence, length and phase position of flanking double‐stranded DNA The FEBS Journal, 282 (1). pp. 4-18. ISSN 1742-464X John, Franklin ; George, Jinu ; Srivastava, Mrinal S ; Hassan, P. A. ; Aswal, V. K. ; Karki, Subhas S. ; Raghavan, Sathees C. (2015) Pluronic copolymer encapsulated SCR7 as a potential anticancer agent Faraday Discussions, 177 . pp. 155-161. ISSN 0301-7249 Katiyar, Arpit ; Hegde, Mahesh ; Kumar, Sujeet ; Gopalakrishnan, Vidya ; Bhatelia, Khyati D. ; Ananthaswamy, Kavya ; Ramareddy, Sureshbabu A. ; De Clercq, Erik ; Choudhary, Bibha ; Schols, Dominique ; Raghavan, Sathees C. ; Karki, Subhas S. (2015) Synthesis and evaluation of the biological activity of N′-[2-oxo-1, 2 dihydro-3 H-indol-3-ylidene] benzohydrazides as potential anticancer agents RSC Advances, 5 (56). pp. 45492-45501. ISSN 2046-2069 Hegde, Mahesh ; Sharath Kumar, Kothanahally S. ; Thomas, Elizabeth ; Ananda, Hanumappa ; Raghavan, Sathees C. ; Rangappa, Kanchugarakoppal S. (2015) A novel benzimidazole derivative binds to the DNA minor groove and induces apoptosis in leukemic cells RSC Advances, 5 (113). pp. 93194-93208. ISSN 2046-2069 Gkotzamanidou, Maria ; Shammas, Masood ; Terpos, Evangelos ; Raghavan, Sathees C. ; Anderson, Kenneth C. ; Munshi, Nikhil C. ; Dimopoulos, Meletios - Athanasios ; Souliotis, Vassilis L. (2014) Deficient double strand breaks repair of bone marrow plasma cells correlates with better clinical outcome of multiple myeloma patients Cancer Research, 74 (19). No pp. given. ISSN 0008-5472 Kumar, Sujeet ; Gopalakrishnan, Vidya ; Hegde, Mahesh ; Rana, Vivek ; Dhepe, Sharad S. ; Ramareddy, Sureshbabu A. ; Leoni, Alberto ; Locatelli, Alessandra ; Morigi, Rita ; Rambaldi, Mirella ; Srivastava, Mrinal ; Karkia, Subhas S. (2014) Synthesis and antiproliferative activity of imidazo [2, 1-b][1, 3, 4] thiadiazole derivatives Bioorganic & Medicinal Chemistry Letters, 24 (19). pp. 4682-4688. ISSN 0960-894X Kumar, Sujeet ; Hegde, Mahesh ; Gopalakrishnan, Vidya ; Renuka, Vinaya Kumar ; Ramareddy, Sureshbabu A. ; De Clercq, Erik ; Schols, Dominique ; Gudibabande Narasimhamurthy, Anil Kumar ; Raghavan, Sathees C. ; Karki, Subhas S. (2014) 2-(4-Chlorobenzyl)-6-arylimidazo [2, 1-b][1, 3, 4] thiadiazoles: synthesis, cytotoxic activity and mechanism of action European Journal of Medicinal Chemistry, 84 . pp. 687-697. ISSN 0223-5234 Sharath Kumar, Kothanahally S. ; Hanumappa, Ananda ; Hegde, Mahesh ; Narasimhamurthy, Kereyagalahally H. ; Raghavan, Sathees C. ; Rangappaa, Kanchugarakoppal S. (2014) Synthesis and antiproliferative effect of novel 4-thiazolidinone-, pyridine-and piperazine-based conjugates on human leukemic cells European Journal of Medicinal Chemistry, 81 . pp. 341-349. ISSN 0223-5234 Srivastava, Mrinal ; Hegde, Mahesh ; Chiruvella, Kishore K. ; Koroth, Jinsha ; Bhattacharya, Souvari ; Choudhary, Bibha ; Raghavan, Sathees C. (2014) Sapodilla plum (Achras sapota) induces apoptosis in cancer cell lines and inhibits tumor progression in mice Scientific Reports, 4 . Article ID 6147, 9 pages. ISSN 2045-2322 Nambiar, Mridula ; Srivastava, Mrinal ; Gopalakrishnan, Vidya ; Sankaran, Sritha K. ; Raghavan, Sathees C. (2013) G-quadruplex structures formed at the HOX11 breakpoint region contribute to its fragility during t (10; 14) translocation in T-cell leukemia Molecular and Cellular Biochemistry, 33 (21). pp. 4266-4281. ISSN 0300-8177 Kavitha, Chandagirikoppal V. ; Nambiar, Mridula ; Narayanaswamy, Pavan B. ; Thomas, Elizabeth ; Rathore, Ujjwal ; Ananda Kumar, Channapillekoppalu S. ; Choudhary, Bibha ; Rangappa, Kanchugarakoppal S. ; Raghavan, Sathees C. (2013) Propyl-2-(8-(3, 4-difluorobenzyl)-2′, 5′-dioxo-8-azaspiro [bicyclo [3.2. 1] octane-3, 4′-imidazolidine]-1′-yl) acetate induces apoptosis in human leukemia cells through mitochondrial pathway following cell cycle arrest PLoS One, 8 (7). Article ID e69103, 10 pages. ISSN 1932-6203 Sahu, Upasana ; Sidhar, Himakshi ; Ghate, Pankaj S. ; Advirao, Gopal M. ; Raghavan, Sathees C. ; Gir, Ranjit K. (2013) A novel anticancer agent, 8-methoxypyrimido [4′, 5′: 4, 5] thieno (2, 3-b) quinoline-4 (3H)-one induces neuro 2a neuroblastoma cell death through p53-dependent, caspase-dependent and-independent apoptotic pathways PLos One, 8 (6). Article ID e66430, 18 pages. ISSN 1932-6203 Sharma, Sheetal ; Panjamurthy, Kuppusamy ; Choudhary, Bibha ; Srivastava, Mrinal ; Shahabuddin, M. S. ; Giri, Ranjit ; Advirao, Gopal M. ; Raghavan, Sathees C. (2013) A novel DNA intercalator, 8‐methoxy pyrimido [4′, 5′: 4, 5] thieno (2, 3‐b) quinoline‐4 (3H)‐one induces apoptosis in cancer cells, inhibits the tumor progression and enhances lifespan in mice with tumor Molecular Carcinogenesis, 52 (6). pp. 413-425. ISSN 0899-1987 Gurupadaswamy, H. D. ; Girisha, V. ; Kavitha, C. V. ; Raghavan, Sathees C. ; Khanum, Shaukath Ara (2013) Synthesis and evaluation of 2, 5-di (4-aryloylaryloxymethyl)-1, 3, 4-oxadiazoles as anti-cancer agents European Journal of Medicinal Chemistry, 63 . pp. 536-543. ISSN 0223-5234 Nambiar, Mridula ; Raghavan, Sathees C. (2013) Chromosomal translocations among the healthy human population: implications in oncogenesis Cellular and Molecular Life Sciences, 70 (8). pp. 1381-1392. ISSN 1420-682X Srivastava, Mrinal ; Nambiar, Mridula ; Sharma, Sheetal ; Karki, Subhas S. ; Goldsmith, G. ; Hegde, Mahesh ; Kumar, Sujeet ; Pandey, Monica ; Singh, Ram K. ; Ray, Pritha ; Natarajan, Renuka ; Kelkar, Madhura ; De, Abhijit ; Choudhary, Bibha ; Raghavan, Sathees C. (2012) An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression Cell, 151 (7). pp. 1474-1487. ISSN 0092-8674 Mayilaadumveettil, Nishana ; Raghavan, Sathees C. (2012) Role of recombination activating genes in the generation of antigen receptor diversity and beyond Immunology, 137 (4). pp. 271-281. ISSN 0019-2805 Nishana, Mayilaadumveettil ; Raghavan, Sathees C. (2012) A non-B DNA can replace heptamer of V(D)J recombination when present along with a nonamer: implications in chromosomal translocations and cancer Biochemical Journal, 448 (1). pp. 115-125. ISSN 0264-6021 Somasagara, Ranganatha R. ; Hegde, Mahesh ; Chiruvella, Kishore K. ; Musini, Anjaneyulu ; Choudhary, Bibha ; Raghavan, Sathees C. (2012) Extracts of strawberry fruits induce intrinsic pathway of apoptosis in breast cancer cells and inhibits tumor progression in mice PLoS One, 7 (10). Article ID e47021-11 pages. ISSN 1932-6203 Gopalakrishnan, Vidya ; Raghavan, Sathees C. (2012) Sequence and structural basis for chromosomal fragility during translocations in cancer Future Oncology, 8 (9). pp. 1121-1134. ISSN 1479-6694 Katapadi, Vijeth K. ; Nambiar, Mridula ; Raghavan, Sathees C. (2012) Potential G-quadruplex formation at breakpoint regions of chromosomal translocations in cancer may explain their fragility Genomics, 100 (2). pp. 72-80. ISSN 0888-7543 Chiruvella, Kishore K. ; Sebastian, Robin ; Sharma, Sheetal ; Karande, Anjali A. ; Choudhary, Bibha ; Raghavan, Sathees C. (2012) Time-dependent predominance of nonhomologous DNA end-joining pathways during embryonic development in mice Journal of Molecular Biology, 417 (3). pp. 197-211. ISSN 0022-2836 Nambiar, Mridula ; Raghavan, Sathees C. (2012) Mechanism of fragility at BCL2 gene minor breakpoint cluster region during t (14; 18) chromosomal translocation The Journal of Biological Chemistry, 287 . pp. 8688-8701. ISSN 0021-9258 Vinaya, Kambappa ; Kavitha, Chandagirikoppal V. ; Prasanna, Doddakunche S. ; Chandrappa, Siddappa ; Ranganatha, Somasagara R. ; Raghavan, Sathees C. ; Rangappa, Kanchugarakoppal S. (2012) Synthesis and antileukemic activity of novel 2‐(4‐(2, 4‐dimethoxybenzoyl) phenoxy)‐1‐(4‐(3‐(piperidin‐4‐yl) propyl) piperidin‐1‐yl) ethanone derivatives Chemical Biology & Drug Design, 79 (3). pp. 360-367. ISSN 1747-0277 Naik, Abani Kanta ; Raghavan, Sathees C. (2012) Differential reaction kinetics, cleavage complex formation, and nonamer binding domain dependence dictate the structure-specific and sequence-specific nuclease activity of RAGs Journal of Molecular Biology, 415 (3). pp. 475-488. ISSN 0022-2836 Choudhary, B. ; Karande, A. A. ; Raghavan, S. C. (2012) Telomere and telomerase in stem cells: relevance in ageing and disease Frontiers in Bioscience, 4 . pp. 16-30. ISSN 1093-9946 Purohit, Madhusudan N. ; Panjamurthy, Kuppusamy ; Elango, Santhini ; Hebbar, Karteek ; Mayur, Yergeri C. ; Raghavan, Sathees C. (2011) In-vitro cytotoxicity and cell cycle analysis of two novel bis-1, 2, 4-triazole derivatives: 1, 4-bis [5-(5-mercapto-1, 3, 4-oxadiazol-2-yl-methyl)-thio-4-(p-tolyl)-1, 2, 4-triazol-3-yl]-butane (MNP-14) and 1, 4-bis [5-(carbethoxy-methyl)-thio-4-(p-ethoxy phenyl)-1, 2, 4-triazol-3-yl]-butane (MNP-16) Nucleosides, Nucleotides and Nucleic Acids, 30 (11). pp. 873-885. ISSN 1525-7770 Vinaya, Kambappa ; Kavitha, Chandagirikoppal V. ; Chandrappa, Siddappa ; Prasanna, Doddakunche S. ; Raghavan, Sathees C. ; Rangappa, Kanchugarakoppal S. (2011) Synthesis and antileukemic activity of novel 4‐(3‐(piperidin‐4‐yl) propyl) piperidine derivatives Chemical Biology & Drug Design, 78 (4). pp. 622-630. ISSN 1747-0277 Teimoori, Simin ; Panjamurthy, Kuppusamy ; Vinaya, Kambappa ; Prasanna, Doddakunche S. ; Raghavan, Sathees C. ; Rangappa, Kanchugarakoppal S. (2011) Synthesis and biological evaluation of novel homopiperazine derivatives as anticancer agents Journal of Cancer Therapy, 2 (4). pp. 507-514. ISSN 2151-1934 Chiruvella, Kishore K. ; Raghavan, Sathees C. (2011) A natural compound, methyl angolensate, induces mitochondrial pathway of apoptosis in Daudi cells Investigational New Drugs, 29 (4). pp. 583-592. ISSN 0167-6997 Shahabuddin, M. S. ; Nambiar, Mridula ; Moorthy, Balaji T. ; Naik, Prakruthi L. ; Choudhary, Bibha ; Advirao, Gopal M. ; Raghavan, Sathees C. (2011) A novel structural derivative of natural alkaloid ellipticine, MDPSQ, induces necrosis in leukemic cells Investigational New Drugs, 29 (4). pp. 523-533. ISSN 0167-6997 Karki, Subhas S. ; Panjamurthy, Kuppusamy ; Kumar, Sujeet ; Nambiar, Mridula ; Ramareddy, Sureshbabu A. ; Chiruvella, Kishore K. ; Raghavan, Sathees C. (2011) Synthesis and biological evaluation of novel 2-aralkyl-5-substituted-6-(4′-fluorophenyl)-imidazo [2, 1-b][1, 3, 4] thiadiazole derivatives as potent anticancer agents European Journal of Medicinal Chemistry, 46 (6). pp. 2109-2116. ISSN 0223-5234 Sharma, Sheetal ; Choudhary, Bibha ; Raghavan, Sathees C. (2011) Efficiency of nonhomologous DNA end joining varies among somatic tissues, despite similarity in mechanism Cellular and Molecular Life Sciences, 68 (4). pp. 661-676. ISSN 1420-682X Nambiar, Mridula ; Raghavan, Sathees C. (2011) How does DNA break during chromosomal translocations? Nucleic Acids Research, 39 (14). pp. 5813-5825. ISSN 0305-1048 Shahabuddin, M. S. ; Nambiar, Mridula ; Advirao, Gopal M. ; Raghavan, Sathees C. (2011) Intercalative pyrimido[4',5':4,5]thieno(2,3-b)quinolines induce apoptosis in leukemic cells: a comparative study of methoxy and morpholino substitution Investigational New Drugs, 29 (5). pp. 873-882. ISSN 0167-6997 Teimoori, S. ; Panjamurthy, K. ; Vinaya, K. ; Prasanna, D. S. ; Batelia, K. ; Raghavan, Sathees C. ; Rangappa, K.S. (2011) Synthesis and antiproliferative activity of novel homopiperazine derivatives in leukemia cells Chemistry & Biology Interface, 1 (1). pp. 59-67. ISSN 2249-4820 Prasanna, D. S. ; Kavitha, C. V. ; Vinaya, K. ; Ranganatha, S. R. ; Raghavan, Sathees C. ; Rangappa, K. S. (2010) Synthesis and identification of a new class of antileukemic agents containing 2-(arylcarboxamide)-(S)-6-amino-4, 5, 6, 7-tetrahydrobenzo [d] thiazole European Journal of Medicinal Chemistry, 45 (11). 5331 -5336. ISSN 0223-5234 Moorthy, Balaji T. ; Ravi, Subban ; Srivastava, Mrinal ; Chiruvella, Kishore K. ; Hemlal, H. ; Joy, Omana ; Raghavan, Sathees C. (2010) Novel rhodanine derivatives induce growth inhibition followed by apoptosis Bioorganic & Medicinal Chemistry Letters, 20 (21). pp. 6297-6301. ISSN 0960-894X Satish Kumar, Tadi ; Kari, Vijayalakshmi ; Choudhary, Bibha ; Nambia, Mridula ; Akila, T. S. ; Raghavan, Sathees C. (2010) Anti-apoptotic protein, BCL2, down-regulates DNA end joining in cancer cells The Journal of Biological Chemistry, 285 . pp. 32657-32670. ISSN 0021-9258 Kumar, Tadi Satish ; Kari, Vijayalakshmi ; Chaudhary, Bibha ; Nambiar, Mridula ; Akila, T. S. ; Raghavan, Sathees C. (2010) Anti-apoptotic protein BCL2 down-regulates DNA end joining in cancer cells The Journal of Biological Chemistry, 285 (42). pp. 32657-32670. ISSN 0021-9258 Chiruvella, Kishore K. ; Panjamurthy, Kuppusamy ; Choudhary, Bibha ; Joy, Omana ; Raghavan, Sathees C. (2010) Methyl angolensate from callus of Indian redwood induces cytotoxicity in human breast cancer cells International Journal of Biomedical Science IJBS, 6 (3). pp. 182-194. ISSN 1550-9702 Prasanna, D. S. ; Kavitha, C. V. ; Raghava, B. ; Vinaya, K. ; Ranganatha, S. R. ; Raghavan, Sathees C. ; Rangappa, K. S. (2010) Synthesis and identification of a new class of (S)-2, 6-diamino-4, 5, 6, 7-tetrahydrobenzo [d] thiazole derivatives as potent antileukemic agents Investigational New Drugs, 28 (4). pp. 454-465. ISSN 0167-6997 Ravi, Subban ; Chiruvella, Kishore K. ; Rajesh, K. ; Prabhu, V. ; Raghavanb, Sathees C. (2010) 5-isopropylidene-3-ethyl rhodanine induce growth inhibition followed by apoptosis in leukemia cells European Journal of Medicinal Chemistry, 45 (7). pp. 2748-2752. ISSN 0223-5234 Avula, Balakrishna ; Chiruvella, Kishore K. ; Reddy, Mudumala V. N. ; Reddy, Rajesh ; Nayak, Sandip K. ; Raghavan, Sathees C. ; Reddy, Cirandur S. (2010) Synthesis, characterization and evaluation of cytotoxicity of new aminophosphonic acid diesters in human leukemia cells Letters in Drug Design & Discovery, 7 (4). pp. 250-259. ISSN 1570-1808 Naik, Abani Kanta ; Lieber, Michael R. ; Raghavan, Sathees C. (2010) Cytosines, but not purines, determine RAG induced breaks on heteroduplex DNA structures: implications for genomic instability Journal of Biological Chemistry, 285 (10). pp. 7587-7597. ISSN 0021-9258 Naik, Abani Kanta ; Lieber, Michael R. ; Raghavan, Sathees C. (2010) Cytosines, but not purines, determine recombination activating gene (rag)-induced breaks on heteroduplex DNA structures implications for genomic instability The Journal of Biological Chemistry, 285 . pp. 7587-7597. ISSN 0021-9258 Asha, D. ; Kavitha, C. V. ; Chandrappa, S. ; Prasanna, D. S. ; Vinaya, K. ; Raghavan, Sathees C. ; Rangappa, K. S. (2010) Novel ethyl 2-(1-aminocyclobutyl)-5-(benzoyloxy)-6-hydroxy-pyrimidine-4-carboxylate derivatives: synthesis and anticancer activities Journal of Cancer Therapy, 1 (1). pp. 21-28. ISSN 2151-1934 Shahabuddin, M. S. ; Nambiar, Mridula ; Choudhary, Bibha ; Advirao, Gopal M. ; Raghavan, Sathees C. (2010) A novel DNA intercalator, butylamino-pyrimido [4′, 5′: 4, 5] selenolo (2, 3-b) quinoline, induces cell cycle arrest and apoptosis in leukemic cells Investigational New Drugs, 28 (1). pp. 35-48. ISSN 0167-6997 Nambiar, Mridula ; Raghavan, Sathees C. (2010) Prevalence and analysis of t (14; 18) and t (11; 14) chromosomal translocations in healthy Indian population Annals of Hematology, 89 . p. 35. ISSN 0939-5555 Sharma, Sheetal ; Raghavan, Sathees C. (2010) Nonhomologous DNA end joining in cell-free extracts Journal of Nucleic Acids, 2010 (2010). Article ID 389129, 11 pages. ISSN 2090-0201 Prasanna, Doddakunche S. ; Kavitha, Chandagirikoppal V. ; Vinaya, Kambappa ; Ranganatha, Somasagara R. ; Raghava, Byregowda ; Sunil Kumar, Yelekere C. ; Raghavan, Sathees C. ; Rangappa, Kanchugarakoppal S. (2010) Synthesis and antileukemic activity of 1-((S)-2-Amino-4, 5, 6, 7-tetrahydrobenzo [d] thiazol-6-yl)-3-(substituted phenyl) urea derivatives Bulletin of the Chemical Society of Japan, 83 (6). pp. 689-697. ISSN 0009-2673 Thimme Gowda, N. R. ; Kavitha, C. V. ; Chiruvella, Kishore K. ; Joy, Omana ; Rangappa, Kanchugarakoppal S. ; Raghavan, Sathees C. (2009) Synthesis and biological evaluation of novel 1-(4-methoxyphenethyl)-1H-benzimidazole-5-carboxylic acid derivatives and their precursors as antileukemic agents Bioorganic & Medicinal Chemistry Letters, 19 (16). pp. 4594-4600. ISSN 0960-894X Ananda Kumar, C. S. ; Kavitha, C. V. ; Vinaya, K. ; Benaka Prasad, S. B. ; Thimmegowda, N. R. ; Chandrappa, S. ; Raghavan, Sathees C. ; Rangappa, K. S. (2009) Synthesis and in vitro cytotoxic evaluation of novel diazaspiro bicyclo hydantoin derivatives in human leukemia cells: a SAR study Investigational New Drugs, 27 (4). pp. 327-337. ISSN 0167-6997 Chandrappa, S. ; Kavitha, C. V. ; Shahabuddin, M. S. ; Vinaya, K. ; Ananda Kumar, C. S. ; Ranganatha, S. R. ; Raghavan, Sathees C. ; Rangappa, K. S. (2009) Synthesis of 2-(5-((5-(4-chlorophenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid derivatives and evaluation of their cytotoxicity and induction of apoptosis in human leukemia cells Bioorganic & Medicinal Chemistry, 17 (6). pp. 2576-2584. ISSN 0968-0896 Shahabuddin, M. S. ; Gopal, M. ; Raghavan, Sathees C. (2009) Intercalating, cytotoxic, antitumour activity of 8-chloro and 4-morpholinopyrimido [4′, 5′: 4, 5] thieno (2, 3-b) quinolines Journal of Photochemistry and Photobiology B: Biology, 94 (1). pp. 13-19. ISSN 1011-1344 Ranganatha, S. R. ; Kavitha, C. V. ; Vinaya, K. ; Prasanna, D. S. ; Chandrappa, S. ; Raghavan, Sathees C, ; Rangappa, Kanchugarakoppal S. (2009) Synthesis and cytotoxic evaluation of novel 2-(4-(2, 2, 2-trifluoroethoxy)-3-methylpyridin-2-ylthio)-1H-benzo [d] imidazole derivatives Archives of Pharmacal Research, 32 . pp. 1335-1343. ISSN 0253-6269 Tsai, Albert G. ; Lu, Haihui ; Raghavan, Sathees C. ; Muschen, Markus ; Hsieh, Chih-Lin ; Lieber, Michael R. (2008) Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity Cell, 135 (6). pp. 1130-1142. ISSN 0092-8674 Chiruvella, Kishore K. ; Kari, Vijayalakshmi ; Choudhary, Bibha ; Nambiar, Mridula ; Ghanta, Rama Gopal ; Raghavan, Sathees C. (2008) Methyl angolensate, a natural tetranortriterpenoid induces intrinsic apoptotic pathway in leukemic cells FEBS Letters, 582 (29). pp. 4066-4076. ISSN 0014-5793 Nambiar, Mridula ; Kari, Vijayalakshmi ; Raghavan, Sathees C. (2008) Chromosomal translocations in cancer Biochimica et Biophysica Acta: Reviews on Cancer, 1786 (2). pp. 139-152. ISSN 0304-419X Naik, Abani Kanta ; Raghavan, Sathees C. (2008) P1 nuclease cleavage is dependent on length of the mismatches in DNA DNA Repair, 7 (8). pp. 1384-1391. ISSN 1568-7864 Nambiar, Mridula ; Choudhary, Bibha ; Rao, Clementina R. ; Raghavan, Sathees C. (2008) Amplification of chromosomal translocation junctions from paraffin-embedded tissues of follicular lymphoma patients Biomedical Materials, 3 (3). Article ID 034103. ISSN 1748-6041 Lieber, Michael R. ; Raghavan, Sathees C. ; Yu, Kefei (2008) Mechanistic aspects of lymphoid chromosomal translocations Journal of the National Cancer Institute - Monographs, 39 . pp. 8-11. ISSN 1052-6773 Chiruvella, Kishore K. ; Mohammed, Arifullah ; Dampur, Gayathri ; Ghanta, Rama Gopal ; Raghavan, Sathees C. (2007) Phytochemical and antimicrobial studies of methyl angolensate and luteolin-7-O-glucoside isolated from callus cultures of Soymida febrifuga International Journal of Biomedical Science, 3 (4). pp. 269-278. ISSN 1555-2810 Raghavan, Sathees C. ; Gu, Jiafeng ; Swanson, Patrick C. ; Lieber, Michael R. (2007) The structure-specific nicking of small heteroduplexes by the RAG complex: implications for lymphoid chromosomal translocations DNA Repair, 6 (6). pp. 751-759. ISSN 1568-7864 Raghavan, Sathees C. ; Lieber, Michael R. (2007) DNA structure and human diseases Frontiers in Bioscience, 12 . pp. 4402-4408. ISSN 1093-9946 Shahabuddin, M. S. ; Gopal, M. ; Raghavan, C. Sathees (2007) Intercalating and antitumour activity of 4-Oxopyrimido[4',5':4,5]thieno(2,3-b)quinoline-4(3H)-one Journal of Cancer Molecules, 3 (5). pp. 139-146. ISSN 1816-0735 Lieber, Michael R. ; Yu, Kefei ; Raghavan, Sathees C. (2006) Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations DNA Repair, 5 (9-10). pp. 1234-1245. ISSN 1568-7864 Raghavan, Sathees C. ; Lieber, Michael R. (2006) DNA structures at chromosomal translocation sites BioEssays, 28 (5). pp. 480-494. ISSN 0265-9247 Raghavan, Sathees C. ; Tong, Jiangen ; Liebe, Michael R. (2006) Hybrid joint formation in human V (D) J recombination requires nonhomologous DNA end joining DNA Repair, 5 (2). pp. 278-285. ISSN 1568-7864 Raghavan, Sathees C. ; Tsai, Albert ; Hsieh, Chih‐Lin ; Lieber, Michael R. (2006) Analysis of non‐B DNA structure at chromosomal sites in the mammalian genome Methods in Enzymology, 409 . pp. 301-316. ISSN 0076-6879 Raghavan, Sathees C. ; Hsieh, Chih-Lin ; Lieber, Michael R. (2005) Both V (D) J coding ends but neither signal end can recombine at the bcl-2 major breakpoint region, and the rejoining is ligase IV dependent Molecular and Cellular Biology, 25 (15). pp. 6475-6484. ISSN 0270-7306 Raghavan, Sathees C. ; Swanson, Patrick C. ; Ma, Yunmei ; Lieber, Michael R. (2005) Double-strand break formation by the RAG complex at the Bcl-2 major breakpoint region and at other non-B DNA structures in vitro Molecular and Cellular Biochemistry, 25 (14). pp. 5904-5919. ISSN 0300-8177 Raghavan, Sathees C. ; Chastain, Paul ; Lee, Jeremy S. ; Hegde, Balachandra G. ; Houston, Sabrina ; Langen, Ralf ; Hsieh, Chih-Lin ; Haworth, Ian S. ; Lieber, Michael R. (2005) Evidence for a triplex DNA conformation at the bcl-2 major breakpoint region of the t(14;18) translocation Journal of Biological Chemistry, 280 (24). pp. 22749-22760. ISSN 0021-9258 Raghavan, Sathees C. ; Houston, Sabrina ; Hegde, Balachandra G. ; Langen, Ralf ; Haworth, Ian S. ; Lieber, Michael R. (2004) Stability and strand asymmetry in the non-B DNA structure at the bcl-2 major breakpoint region The Journal of Biological Chemistry, 279 . pp. 46213-46225. ISSN 0021-9258 Raghavan, Sathees C. ; Raman, Mercy J. (2004) Nonhomologous end joining of complementary and noncomplementary DNA termini in mouse testicular extracts DNA Repair, 3 (10). pp. 1297-1310. ISSN 1568-7864 Raghavan, Sathees C. ; Lieber, Michael R. (2004) Chromosomal translocations and non-B DNA structures in the human genome Cell Cycle, 3 (6). pp. 760-766. ISSN 1538-4101 Raghavan, Sathees C. ; Swanson, Patrick C. ; Wu, Xiantuo ; Hsieh, Chih-Lin ; Lieber, Michael R. (2004) A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex Nature, 428 (6978). pp. 88-93. ISSN 0028-0836 Raghavan, Sathees C. ; Kirsch, Ilan R. ; Lieber, Michael R. (2001) Analysis of the V(D)J recombination efficiency at lymphoid chromosomal translocation breakpoints Journal of Biological Chemistry, 276 (31). pp. 29126-29133. ISSN 0021-9258 Anand, Anuranjan ; Dasgupta, Aindrilla ; Sudha, S. ; Raghavan, S. ; Sharat Chandra, H. (1998) A search for additional X-linked genes affecting sex determination inDrosophila melanogaster Journal of Genetics, 77 (1). pp. 27-36. ISSN 0022-1333 Raveendran, Deepthi ; Raghavan, Sathees C. Biochemical characterization of nonamer binding domain of RAG1 reveals its thymine preference with respect to length and position Scientific Reports, 6 . Article ID 19091, 13 pages. ISSN 2045-2322 |