Nambiar, Mridula ; Raghavan, Sathees C. (2013) Chromosomal translocations among the healthy human population: implications in oncogenesis Cellular and Molecular Life Sciences, 70 (8). pp. 1381-1392. ISSN 1420-682X
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Official URL: http://link.springer.com/article/10.1007/s00018-01...
Related URL: http://dx.doi.org/10.1007/s00018-012-1135-x
Abstract
Chromosomal translocations are characteristic features of many cancers, especially lymphoma and leukemia. However, recent reports suggest that many chromosomal translocations can be found in healthy individuals, although the significance of this observation is still not clear. In this review, we summarize recent studies on chromosomal translocations in healthy individuals carried out in different geographical areas of the world and discuss the relevance of the observation with respect to oncogenesis.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Springer Verlag. |
| Keywords: | Leukemia; Lymphoma; Neoplasia; Carcinoma; Sarcoma; Genomic Instability; V(D)J Recombination |
| ID Code: | 104055 |
| Deposited On: | 11 Apr 2017 15:52 |
| Last Modified: | 11 Apr 2017 15:52 |
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