Browse by Fellow

Banerjee, Tanushree ; Sharma, Shailendra Kumar ; Kapoor, Neha ; Dwivedi, Vishnu ; Surolia, Namita ; Surolia, Avadhesha (2011) Benzothiophene carboxamide derivatives as inhibitors of Plasmodium falciparum enoyl-ACP reductase IUBMB Life, 63 (12). pp. 1101-1110. ISSN 1521-6543

Banerjee, Tanushree ; Kapoor, Neha ; Surolia, Namita ; Surolia, Avadhesha (2011) Benzothiophene carboxamide derivatives as novel Antimalarials IUBMB Life, 63 (12). pp. 1111-1115. ISSN 1521-6543

Maity, Koustav ; Venkata, Bharat Somireddy ; Kapoor, Neha ; Surolia, Namita ; Surolia, Avadhesha ; Suguna, Kaza (2011) Structural basis for the functional and inhibitory mechanisms of β-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Plasmodium falciparum Journal of Structural Biology, 176 (2). pp. 238-249. ISSN 1047-8477

Maity, Koustav ; Banerjee, Tanushree ; Prabakaran, Narayanappa ; Surolia, Namita ; Surolia, Avadhesha ; Suguna, Kaza (2011) Effect of substrate binding loop mutations on the structure, kinetics, and inhibition of enoyl acyl carrier protein reductase from Plasmodium falciparum IUBMB Life, 63 (1). pp. 30-41. ISSN 1521-6543

Maity, Koustav ; Bhargav, Saligram Prabhakar ; Sankaran, Banumathi ; Surolia, Namita ; Surolia, Avadhesha ; Suguna, Kaza (2010) X-ray crystallographic analysis of the complexes of enoyl acyl carrier protein reductase of Plasmodium falciparum with triclosan variants to elucidate the importance of different functional groups in enzyme inhibition IUBMB Life, 62 (6). pp. 467-476. ISSN 1521-6543

Kumar, Gyanendra ; Banerjee, Tanushree ; Kapoor, Neha ; Surolia, Namita ; Surolia, Avadhesha (2010) SAR and pharmacophore models for the rhodanine inhibitors of Plasmodium falciparum enoyl-acyl carrier protein reductase IUBMB Life, 62 (3). pp. 204-213. ISSN 1521-6543

Upadhyay, Santosh Kumar ; Misra, Ashish ; Surolia, Namita ; Surolia, Avadhesha ; Sundd, Monica (2010) Backbone chemical shift assignments of the acyl-acyl carrier protein intermediates of the fatty acid biosynthesis pathway of Plasmodium falciparum Biomolecular NMR Assignments, 4 (1). pp. 83-85. ISSN 1874-2718

Kapoor, Neha ; Banerjee, Tanushree ; Babu, Ponnusamy ; Maity, Koustav ; Surolia, Namita ; Surolia, Avadhesha (2009) Design, development, synthesis, and docking analysis of 2'-substituted triclosan analogs as inhibitors for Plasmodium falciparum Enoyl-ACP reductase IUBMB Life, 61 (11). pp. 1083-1091. ISSN 1521-6543

Singh, Agam Prasad ; Surolia, Namita ; Surolia, Avadhesha (2009) Triclosan inhibit the growth of the late liver-stage of Plasmodium IUBMB Life, 61 (9). pp. 923-928. ISSN 1521-6543

Upadhyay, Santosh Kumar ; Misra, Ashish ; Srivastava, Richa ; Surolia, Namita ; Surolia, Avadhesha ; Sundd, Monica (2009) Structural insights into the acyl intermediates of the Plasmodium falciparum fatty acid synthesis pathway: the mechanism of expansion of the acyl carrier protein core Journal of Biological Chemistry, 284 . pp. 22390-22400. ISSN 0021-9258

Misra, Ashish ; Surolia, Namita ; Surolia, Avadhesha (2009) Evolutionary significance of self-acylation property in acyl carrier proteins IUBMB Life, 61 (8). pp. 853-859. ISSN 1521-6543

Sharma, Shilpi ; Sharma, Shailendra Kumar ; Surolia, Namita ; Surolia, Avadhesha (2009) β-Ketoacyl-ACP synthase I/II from Plasmodium falciparum (PfFabB/F)-is it B or F? IUBMB Life, 61 (6). pp. 658-662. ISSN 1521-6543

Gupta, Sarika ; Modak, Rahul ; Surolia, Namita ; Surolia, Avadhesha (2009) Partial molar volumes of acyl carrier proteins are related to their states of acylation Biochemical and Biophysical Research Communications, 380 (4). pp. 763-768. ISSN 0006-291X

Misra, Ashish ; Surolia, Namita ; Surolia, Avadhesha (2009) Catalysis and mechanism of malonyl transferase activity in type II fatty acid biosynthesis acyl carrier proteins Molecular BioSystems, 5 (6). pp. 651-659. ISSN 1742-206X

Banerjee, Tanushree ; Sharma, Shailendra Kumar ; Surolia, Namita ; Surolia, Avadhesha (2008) Epigallocatechin gallate is a slow-tight binding inhibitor of enoyl-ACP reductase from Plasmodium falciparum Biochemical and Biophysical Research Communications, 377 (4). pp. 1238-1242. ISSN 0006-291X

Karmodiya, Krishanpal ; Modak, Rahul ; Sahoo, Nirakar ; Sajad, Syed ; Surolia, Namita (2008) Deciphering the key residues in Plasmodium falciparum β-ketoacyl acyl carrier protein reductase responsible for interactions with Plasmodium falciparum acyl carrier protein FEBS Journal, 275 (19). pp. 4756-4766. ISSN 1742-464X

Mishra, Satyendra ; Karmodiya, Krishanpal ; Parasuraman, Prasanna ; Surolia, Avadhesha ; Surolia, Namita (2008) Design, synthesis, and application of novel triclosan prodrugs as potential antimalarial and antibacterial agents Bioorganic & Medicinal Chemistry, 16 (10). pp. 5536-5546. ISSN 0968-0896

Mishra, Satyendra ; Karmodiya, Krishanpal ; Surolia, Namita ; Surolia, Avadhesha (2008) Synthesis and exploration of novel curcumin analogues as anti-malarial agents Bioorganic & Medicinal Chemistry, 16 (6). pp. 2894-2902. ISSN 0968-0896

Gratraud, Paul ; Surolia, Namita ; Besra, Gurdyal S. ; Surolia, Avadhesha ; Kremer, Laurent (2008) Antimycobacterial activity and mechanism of action of NAS-91 Antimicrobial Agents and Chemotherapy, 52 (3). pp. 1162-1166. ISSN 0066-4804

Karmodiya, Krishanpal ; Surolia, Namita (2008) A unique and differential effect of denaturants on cofactor mediated activation of Plasmodium falciparum β -ketoacyl-ACP reductase Proteins: Structure, Function, and Bioinformatics, 70 (2). pp. 528-538. ISSN 0887-3585

Misra, Ashish ; Sharma, Shailendra Kumar ; Surolia, Namita ; Surolia, Avadhesha (2007) Self-acylation properties of type II fatty acid biosynthesis acyl carrier protein Chemistry & Biology, 14 (7). pp. 775-783. ISSN 1074-5521

Modak, Rahul ; Sinha, Sharmistha ; Surolia, Namita (2007) Isothermal unfolding studies on the apo and holo forms of Plasmodium falciparum acyl carrier protein role of the 4'-phosphopantetheine group in the stability of the holo form of Plasmodium falciparum acyl carrier protein FEBS Journal, 274 (13). pp. 3313-3326. ISSN 1742-464X

Sharma, Shilpi ; Sharma, Shailendra Kumar ; Modak, Rahul ; Karmodiya, Krishanpal ; Surolia, Namita ; Surolia, Avadhesha (2007) Mass spectrometry-based systems approach for identification of inhibitors of Plasmodium falciparum fatty acid synthase Antimicrobial Agents and Chemotherapy, 51 (7). pp. 2552-2558. ISSN 0066-4804

Kumar, Gyanendra ; Parasuraman, Prasanna ; Sharma, Shailendra Kumar ; Banerjee, Tanushree ; Karmodiya, Krishanpal ; Surolia, Namita ; Surolia, Avadhesha (2007) Discovery of a rhodanine class of compounds as inhibitors of Plasmodium falciparum enoyl-acyl carrier protein reductase Journal of Medicinal Chemistry, 50 (11). pp. 2665-2675. ISSN 0022-2623

Ramya, T. N. C. ; Karmodiya, Krishanpal ; Surolia, Avadhesha ; Surolia, Namita (2007) 15-Deoxyspergualin primarily targets the trafficking of apicoplast proteins in Plasmodium falciparum Journal of Biological Chemistry, 282 (9). pp. 6388-6397. ISSN 0021-9258

Sharma, Shailendra Kumar ; Parasuraman, Prasanna ; Kumar, Gyanendra ; Surolia, Namita ; Surolia, Avadhesha (2007) Green tea catechins potentiate triclosan binding to enoyl-ACP reductase from Plasmodium falciparum (PfENR) Journal of Medicinal Chemistry, 50 (4). pp. 765-775. ISSN 0022-2623

Ramya, T. N. C. ; Mishra, Satyendra ; Karmodiya, Krishanpal ; Surolia, Namita ; Surolia, Avadhesha (2007) Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum Antimicrobial Agents and Chemotherapy, 51 (1). pp. 307-316. ISSN 0066-4804

Ramya, T. N. C. ; Surolia, Namita ; Surolia, Avadhesha (2007) 15-Deoxyspergualin inhibits eukaryotic protein synthesis through eIF2α phosphorylation Biochemical Journal, 401 . pp. 411-420. ISSN 0264-6021

Karmodiya, Krishanpal ; Sajad, Syed ; Sinha, Sharmistha ; Maity, Koustav ; Suguna, Kaza ; Surolia, Namita (2007) Conformational stability and thermodynamic characterization of homotetrameric Plasmodium falciparum β-ketoacyl-ACP reductase IUBMB Life, 59 (7). pp. 441-449. ISSN 1521-6543

Swarnamukhi, P. L. ; Sharma, S. K. ; Padala, P. ; Surolia, N. ; Surolia, A. ; Suguna, K. (2007) Packing and loop-structure variations in non-isomorphous crystals of FabZ from Plasmodium falciparum Acta Crystallographica Section D, 63 . pp. 458-464. ISSN 0907-4449

Chhibber, Manmohan ; Kumar, Gyanendra ; Parasuraman, Prasanna ; Ramya, T. N. C. ; Surolia, Namita ; Surolia, Avadhesha (2006) Novel diphenyl ethers: design, docking studies, synthesis and inhibition of enoyl ACP reductase of Plasmodium falciparum and Escherichia coli Bioorganic & Medicinal Chemistry, 14 (23). pp. 8086-8098. ISSN 0968-0896

Ramya, T. N. C. ; Surolia, Namita ; Surolia, Avadhesha (2006) 15-Deoxyspergualin modulates Plasmodium falciparum heat shock protein function Biochemical and Biophysical Research Communications, 348 (2). pp. 585-592. ISSN 0006-291X

Ramya, T. N. C. ; Surolia, Namita ; Surolia, Avadhesha (2006) Polyamine synthesis and salvage pathways in the malaria parasite Plasmodium falciparum Biochemical and Biophysical Research Communications, 348 (2). pp. 579-584. ISSN 0006-291X

Karmodiya, Krishanpal ; Surolia, Namita (2006) Analyses of co-operative transitions in Plasmodium falciparum β-ketoacyl acyl carrier protein reductase upon co-factor and acyl carrier protein binding FEBS Journal, 273 (17). pp. 4093-4103. ISSN 1742-464X

Sharma, Alok Kumar ; Sharma, Shailendra Kumar ; Surolia, Avadhesha ; Surolia, Namita ; Sarma, Siddhartha P. (2006) Solution structures of conformationally equilibrium forms of holo-acyl carrier protein (PfACP) from Plasmodium falciparum provides insight into the mechanism of activation of ACPs Biochemistry, 45 (22). pp. 6904-6916. ISSN 0006-2960

Lakshmi Swarnamukhi, P. ; Sharma, Shailendra Kumar ; Bajaj, Preeti ; Surolia, Namita ; Surolia, Avadhesha ; Suguna, Kaza (2006) Crystal structure of dimeric FabZ of Plasmodium falciparum reveals conformational switching to active hexamers by peptide flips FEBS Letters, 580 (11). pp. 2653-2660. ISSN 0014-5793

Kumar, Sanjay ; Kumar, Gyanendra ; Kapoor, Mili ; Surolia, Avadhesha ; Surolia, Namita (2006) Synthesis and evaluation of substituted pyrazoles: potential antimalarials targeting the enoyl-ACP reductase of Plasmodium falciparum Synthetic Communications, 36 (2). pp. 215-226. ISSN 0039-7911

Kesavulu, M. M. ; Gowda, A. S. Prakasha ; Ramya, T. N. C. ; Surolia, N. ; Suguna, K. (2005) Plasmepsin inhibitors: design, synthesis, inhibitory studies and crystal structure analysis The Journal of Peptide Research, 66 (4). pp. 211-219. ISSN 1397-002X

Karmodiya, Krishanpal ; Kumar Srivastav, Ratnesh ; Surolia, Namita (2005) Production and purification of refolded recombinant Plasmodium falciparum β-ketoacyl-ACP reductase from inclusion bodies Protein Expression and Purification, 42 (1). pp. 131-136. ISSN 1046-5928

Sharma, Shailendra Kumar ; Modak, Rahul ; Sharma, Shilpi ; Sharma, Alok Kumar ; Sarma, Siddhartha P. ; Surolia, Avadhesha ; Surolia, Namita (2005) A novel approach for over-expression, characterization, and isotopic enrichment of a homogeneous species of acyl carrier protein from Plasmodium falciparum Biochemical and Biophysical Research Communications, 330 (4). pp. 1019-1026. ISSN 0006-291X

Ramya, T. N. C. ; Surolia, N. ; Surolia, A. (2005) Is the fatty acid synthesis pathway a good target for anti-malarial therapy? IUBMB Life, 57 . pp. 371-373. ISSN 1521-6543

Bhor, Vikrant M. ; Thomas, Celestine J. ; Surolia, Namita ; Surolia, Avadhesha (2005) Polymyxin B: an ode to an old antidote for endotoxic shock Molecular BioSystems, 1 . pp. 213-222. ISSN 1742-206X

Pidugu, Lakshmi Swarnamukhi ; Kapoor, Mili ; Surolia, Namita ; Surolia, Avadhesha ; Suguna, Kaza (2004) Structural basis for the variation in triclosan affinity to enoyl reductases Journal of Molecular Biology, 343 (1). pp. 147-155. ISSN 0022-2836

Lakshmi Swarna Mukhi, P. ; Kumar Sharma, S. ; Kapoor, M. ; Surolia, N. ; Surolia, A. ; Suguna, K. (2004) Crystallization and preliminary crystallographic analysis of β-hydroxyacyl ACP dehydratase (FabZ) from Plasmodium falciparum Acta Crystallographica Section D, 60 . pp. 120-121. ISSN 0907-4449

Surolia, Avadhesha ; Ramya, T. N. C. ; Ramya, V. ; Surolia, Namita (2004) 'FAS't inhibition of malaria Biochemical Journal, 383 . pp. 401-412. ISSN 0264-6021

Kapoor, Mili ; Swarna Mukhi, P. L. ; Surolia, Namita ; Suguna, K. ; Surolia, Avadhesha (2004) Kinetic and structural analysis of the increased affinity of enoyl-ACP (acyl-carrier protein) reductase for triclosan in the presence of NAD⁺ Biochemical Journal, 381 . pp. 725-733. ISSN 0006-2936

Kapoor, Mili ; Gopalakrishnapai, Jayashree ; Surolia, Namita ; Surolia, Avadhesha (2004) Mutational analysis of the triclosan-binding region of enoyl-ACP (acyl-carrier protein) reductase from Plasmodium falciparum Biochemical Journal, 381 (3). pp. 735-741. ISSN 0006-2936

Kumar, Sanjay ; Kapoor, Mili ; Surolia, Namita ; Surolia, Avadhesha (2004) One step synthesis of 2-hydroxydiarylether by using domestic microwave heating Synthetic Communications, 34 (3). pp. 413-420. ISSN 0039-7911

Kapoor, Mili ; Chandramouli Reddy, C. ; Krishnasastry, M. V. ; Surolia, Namita ; Surolia, Avadhesha (2004) Slow-tight-binding inhibition of enoyl-acyl carrier protein reductase from Plasmodium falciparum by triclosan Biochemical Journal, 381 . pp. 719-724. ISSN 0006-2936

Sharma, Shilpi ; Ramya, T. N. C. ; Surolia, Avadhesha ; Surolia, Namita (2003) Triclosan as a systemic antibacterial agent in a mouse model of acute bacterial challenge Antimicrobial Agents and Chemotherapy, 47 (12). pp. 3859-3866. ISSN 0066-4804

Sharma, Shailendra Kumar ; Kapoor, Mili ; Ramya, T. N. C. ; Kumar, Sanjay ; Kumar, Gyanendra ; Modak, Rahul ; Sharma, Shilpi ; Surolia, Namita ; Surolia, Avadhesha (2003) Identification, characterization, and inhibition of Plasmodium falciparum β-hydroxyacyl-acyl carrier protein dehydratase (FabZ) Journal of Biological Chemistry, 278 (46). pp. 45661-45671. ISSN 0021-9258

Muralidharan, J. ; Suguna, K. ; Surolia, A. ; Surolia, N. (2003) Exploring the interaction energies for the binding of hydroxydiphenyl ethers to enoyl-acyl carrier protein reductases Journal of Biomolecular Structure & Dynamics, 20 (4). pp. 589-594. ISSN 0739-1102

Ramachandra Rao, Satish P. ; Surolia, Avadhesha ; Surolia, Namita (2003) Triclosan: a shot in the arm for antimalarial chemotherapy Molecular and Cellular Biochemistry, 253 (1-2). pp. 55-63. ISSN 0300-8177

Ramya, T. N. C. ; Surolia, Namita ; Surolia, Avadhesha (2002) Survival strategies of the malarial parasite Plasmodium falciparum Current Science, 83 (7). pp. 818-825. ISSN 0011-3891

Surolia, Namita ; RamachandraRao, Satish P. ; Surolia, Avadhesha (2002) Paradigm shifts in malaria parasite biochemistry and anti-malarial chemotherapy BioEssays, 24 (2). pp. 192-196. ISSN 0265-9247

Kapoor, Mili ; Jamal Darb, M. ; Surolia, Avadhesha ; Surolia, Namita (2001) Kinetic determinants of the interaction of enoyl-ACP reductase from Plasmodium falciparum with its substrates and inhibitors Biochemical and Biophysical Research Communications, 289 (4). pp. 832-837. ISSN 0006-291X

Bhat, G. P. ; Surolia, N. (2001) In vitro antimalarial activity of extracts of three plants used in the traditional medicine of India The American Journal of Tropical Medicine and Hygiene, 65 (4). pp. 304-308. ISSN 0002-9637

Thomas, Celestine J. ; Surolia, Namita ; Surolia, Avadhesha (2001) Kinetic and thermodynamic analysis of the interactions of 23-residue peptides with endotoxin Journal of Biological Chemistry, 276 (38). pp. 35701-35706. ISSN 0021-9258

Suguna, Kaza ; Surolia, Avadhesha ; Surolia, Namita (2001) Structural basis for triclosan and NAD binding to enoyl-ACP reductase of Plasmodium falciparum Biochemical and Biophysical Research Communications, 283 (1). pp. 224-228. ISSN 0006-291X

Surolia, Namita ; Surolia, Avadhesha (2001) Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of Plasmodium falciparum Nature Medicine, 7 . pp. 167-173. ISSN 1078-8956

Bachhawat, Kiran ; Thomas, Celestine J. ; Surolia, Namita ; Surolia, Avadhesha (2000) Interaction of chloroquine and its analogues with heme: an isothermal titration calorimetric study Biochemical and Biophysical Research Communications, 276 (3). pp. 1075-1079. ISSN 0006-291X

Swaminathan, Chittoor P. ; Gupta, Aditi ; Surolia, Namita ; Surolia, Avadhesha (2000) Plasticity in the primary binding site of galactose/N-acetylgalactosamine-specific lectins: implication of the C-H···O hydrogen bond at the specificity-determining C-4 locus of the saccharide in 4-methoxygalactose recognition by jacalin and winged bean (basic) agglutinin I Journal of Biological Chemistry, 275 (37). pp. 28483-28487. ISSN 0021-9258

Surolia, Namita (2000) Receptor-mediated targeting of toxins to intraerythrocytic parasite Plasmodium falciparum Advanced Drug Delivery Reviews, 41 (2). pp. 163-170. ISSN 0169-409X

Thomas, Celestine J. ; Surolia, Namita ; Surolia, Avadhesha (1999) Surface plasmon resonance studies resolve the enigmatic endotoxin neutralizing activity of polymyxin B Journal of Biological Chemistry, 274 (42). pp. 29624-29627. ISSN 0021-9258

Thomas, Celestine J. ; Gangadhar, Beechanahalli P. ; Surolia, Namita ; Surolia, Avadhesha (1998) Kinetics and mechanism of the recognition of endotoxin by polymyxin B Journal of the American Chemical Society, 120 (48). pp. 12428-12434. ISSN 0002-7863

Swaminathan, Chittoor P. ; Surolia, Namita ; Surolia, Avadhesha (1998) Role of Water in the specific binding of mannose and mannooligosaccharides to concanavalin A Journal of the American Chemical Society, 120 (21). pp. 5153-5159. ISSN 0002-7863

Surolia, Namita ; Misquith, Sandra (1996) Cell surface receptor directed targeting of toxin to human malaria parasite, Plasmodium falciparum FEBS Letters, 396 (1). pp. 57-61. ISSN 0014-5793

Singha, Netai C. ; Surolia, Namita ; Surolia, A. (1996) On the relationship of thermodynamic parameters with the buried surface area in protein-ligand complex formation Bioscience Reports, 16 (1). pp. 1-10. ISSN 0144-8463

Srimal, Subita ; Surolia, Namita ; Balasubramanian, S. ; Surolia, Avadhesha (1996) Titration calorimetric studies to elucidate the specificity of the interactions of polymyxin B with lipopolysaccharides and lipid A Biochemical Journal, 315 . pp. 676-686. ISSN 0006-2936

Surolia, N. ; Karthikeyan, G. ; Padmanaban, G. (1993) Involvement of cytochrome P450 in conferring chloroquine resistance to the malarial parasite, Plasmodium falciparum Biochemical and Biophysical Research Communications, 197 (2). pp. 562-569. ISSN 0006-291X

Surolia, Namita ; Padmanaban, Govindarajan (1992) De novo biosynthesis of heme offers a new chemotherapeutic target in the human malarial parasite Biochemical and Biophysical Research Communications, 187 (2). pp. 744-750. ISSN 0006-291X

Surolia, Namita ; Padmanaban, Govindarajan (1991) Chloroquine inhibits heme-dependent protein synthesis in Plasmodium falciparum Proceedings of the National Academy of Sciences of the United States of America, 88 (11). pp. 4786-4790. ISSN 0027-8424

Surolia, Namita ; Krishnamurthy, K. ; Adiga, P. R. (1985) Enzymic basis of deranged foetal flavin-nucleotide metabolism consequent on immunoneutralization of maternal riboflavin carrier protein in the pregnant rat Biochemical Journal, 230 . pp. 363-367. ISSN 0264-6021

Krishnamurthy, Kavita ; Surolia, Namita ; Adiga, P. Radhakantha (1984) Mechanism of foetal wastage following immunoneutralization of riboflavin carrier protein in the pregnant rat: disturbances in flavin coenzyme levels FEBS Letters, 178 (1). pp. 87-91. ISSN 0014-5793

Khan, M. Islam ; Mathew, M. K. ; Mazumdar, T. ; Pain, D. ; Surolia, N. ; Das, M. K. ; Balaram, P. ; Surolia, A. (1983) Fluorescence polarization as a tool to study lectin-sugar interaction Journal of Biosciences, 5 (1). pp. 31-39. ISSN 0250-5991

Islam Khan, M. ; Surolia, Avadhesha ; Surolia, Namita ; Mathew, Mathew K. ; Balaram, Padmnabhan (1981) Fluorescence polarization as a tool to study lectin-sugar interaction: an investigation of the binding of 4-methylumbelliferyl β-D-galactopyranoside to Abrus precatorious agglutinin European Journal of Biochemistry, 115 (1). pp. 149-152. ISSN 0014-2956