Upadhyay, Santosh Kumar ; Misra, Ashish ; Surolia, Namita ; Surolia, Avadhesha ; Sundd, Monica (2010) Backbone chemical shift assignments of the acyl-acyl carrier protein intermediates of the fatty acid biosynthesis pathway of Plasmodium falciparum Biomolecular NMR Assignments, 4 (1). pp. 83-85. ISSN 1874-2718
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Official URL: http://www.springerlink.com/content/606t2472017u04...
Related URL: http://dx.doi.org/10.1007/s12104-010-9212-2
Abstract
We report the backbone chemical shift assignments of the acyl-acyl carrier protein (ACP) intermediates of the fatty acid biosynthesis pathway of Plasmodium falciparum. The acyl-ACP intermediates butyryl (C4), -octanoyl (C8), -decanoyl (C10), -dodecanoyl (C12) and -tetradecanoyl (C14)-ACPs display marked changes in backbone HN, Cα and Cβ chemical shifts as a result of acyl chain insertion into the hydrophobic core. Chemical shift changes cast light on the mechanism of expansion of the acyl carrier protein core.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Springer. |
| Keywords: | Backbone Assignments; Acyl-ACPs; Plasmodium falciparum; Fatty Acid Biosynthesis |
| ID Code: | 56680 |
| Deposited On: | 25 Aug 2011 10:27 |
| Last Modified: | 03 Oct 2011 14:12 |
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