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Number of items: 84. Baidya, Mithu ; Chaturvedi, Madhu ; Agnihotri, Hemlata Dwivedi ; Ranjan, Ashutosh ; Devost, Dominic ; Namkung, Yoon ; Stepniewski, Tomasz Maciej ; Pandey, Shubhi ; Baruah, Minakshi ; Panigrahi, Bhanupriya ; Sarma, Parishmita ; Yadav, Manish K. ; Maharana, Jagannath ; Banerjee, Ramanuj ; Kawakami, Kouki ; Inoue, Asuka ; Selent, Jana ; Laporte, Stéphane A. ; Hébert, Terence E. ; Shukla, Arun K. (2022) Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody Nature Communications, 13 . Kolb, Peter ; Kenakin, Terry ; Alexander, Stephen P. H. ; Bermudez, Marcel ; Bohn, Laura M. ; Breinholt, Christian S. ; Bouvier, Michel ; Hill, Stephen J. ; Kostenis, Evi ; Martemyanov, Kirill A. ; Neubig, Rick R. ; Onaran, H. Ongun ; Rajagopal, Sudarshan ; Roth, Bryan L. ; Selent, Jana ; Shukla, Arun K. ; Sommer, Martha E. ; Gloriam, David E. (2022) Community guidelines for GPCR ligand bias: IUPHAR review 32 British Journal of Pharmacology, 179 (14). pp. 3651-3674. ISSN 0007-1188 Maharana, Jagannath ; Banerjee, Ramanuj ; Yadav, Manish K. ; Sarma, Parishmita ; Shukla, Arun K. (2022) Emerging structural insights into GPCR–β-arrestin interaction and functional outcomes Current Opinion in Structural Biology, 75 . p. 102406. ISSN 0959440X Saha, Shirsha ; Ranjan, Ashutosh ; Godara, Monika ; Shukla, Arun K. (2022) In-cellulo chemical cross-linking to visualize protein-protein interactions Methods in Cell Biology, 169 . pp. 295-307. ISSN 0091679X Sarma, Parishmita ; Saha, Shirsha ; Shukla, Arun K. (2022) Making the switch: The role of Gq in driving GRK selectivity at GPCRs Science Signaling, 15 (726). ISSN 1945-0877 Sarma, Parishmita ; Shukla, Arun K. (2022) Resonating with the signaling bias of CXCR7 Molecular Cell, 82 (18). pp. 3318-3320. ISSN 10972765 (In Press) Maharana, Jagannath ; Sarma, Parishmita ; Shukla, Arun K. (2022) Scratching the itch with cryo-EM Nature Chemical Biology, 18 (3). pp. 242-243. ISSN 1552-4450 Sarma, Parishmita ; Banerjee, Ramanuj ; Shukla, Arun K. (2022) Structural snapshot of a β-arrestin-biased receptor Trends in Pharmacological Sciences . ISSN 01656147 (In Press) Dwivedi-Agnihotri, Hemlata ; Sarma, Parishmita ; Deeksha, S. ; Kawakami, Kouki ; Inoue, Asuka ; Shukla, Arun K. (2022) An intrabody sensor to monitor conformational activation of β-arrestins Methods in Cell Biology, 169 . pp. 267-278. ISSN 0091679X Shiraishi, Yutaro ; Kofuku, Yutaka ; Ueda, Takumi ; Pandey, Shubhi ; Dwivedi-Agnihotri, Hemlata ; Shukla, Arun K. ; Shimada, Ichio (2021) Biphasic activation of β-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR Nature Communications, 12 (1). ISSN 2041-1723 Che, Tao ; Dwivedi-Agnihotri, Hemlata ; Shukla, Arun K. ; Roth, Bryan L. (2021) Biased ligands at opioid receptors: Current status and future directions Science Signaling, 14 (677). ISSN 1945-0877 Maharana, Jagannath ; Shukla, Arun K. (2021) Feeling at home: Structure of the NTSR1–Gi complex in a lipid environment Nature Structural & Molecular Biology, 28 (4). pp. 331-333. ISSN 1545-9993 Pandey, Shubhi ; Kumari, Punita ; Baidya, Mithu ; Kise, Ryoji ; Cao, Yubo ; Dwivedi-Agnihotri, Hemlata ; Banerjee, Ramanuj ; Li, Xaria X. ; Cui, Cedric S. ; Lee, John D. ; Kawakami, Kouki ; Maharana, Jagannath ; Ranjan, Ashutosh ; Chaturvedi, Madhu ; Jhingan, Gagan Deep ; Laporte, Stéphane A. ; Woodruff, Trent M. ; Inoue, Asuka ; Shukla, Arun K. (2021) Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors Molecular Cell, 81 (22). 4605-4621.e11. ISSN 10972765 Zhang, Haitao ; Luginina, Aleksandra ; Mishin, Alexey ; Baidya, Mithu ; Shukla, Arun K. ; Cherezov, Vadim (2021) Structural insights into ligand recognition and activation of angiotensin receptors Trends in Pharmacological Sciences, 42 (7). pp. 577-587. ISSN 01656147 Goncharuk, Marina V. ; Roy, Debarati ; Dubinnyi, Maxim A. ; Nadezhdin, Kirill D. ; Srivastava, Ashish ; Baidya, Mithu ; Dwivedi-Agnihotri, Hemlata ; Arseniev, Alexander S. ; Shukla, Arun K. (2020) Purification of native CCL7 and its functional interaction with selected chemokine receptors Protein Expression and Purification, 171 . p. 105617. ISSN 10465928 Chaturvedi, Madhu ; Shukla, Arun K. (2020) Calcium as a biased cofactor Science, 368 (6489). pp. 369-370. ISSN 0036-8075 Woodruff, Trent M. ; Shukla, Arun K. (2020) The Complement C5a-C5aR1 GPCR Axis in COVID-19 Therapeutics Trends in Immunology, 41 (11). pp. 965-967. ISSN 14714906 Min, Kyungjin ; Yoon, Hye-Jin ; Park, Ji Young ; Baidya, Mithu ; Dwivedi-Agnihotri, Hemlata ; Maharana, Jagannath ; Chaturvedi, Madhu ; Chung, Ka Young ; Shukla, Arun K. ; Lee, Hyung Ho (2020) Crystal Structure of β-Arrestin 2 in Complex with CXCR7 Phosphopeptide Structure, 28 (9). 1014-1023.e4. ISSN 09692126 Dwivedi-Agnihotri, Hemlata ; Chaturvedi, Madhu ; Baidya, Mithu ; Stepniewski, Tomasz Maciej ; Pandey, Shubhi ; Maharana, Jagannath ; Srivastava, Ashish ; Caengprasath, Natarin ; Hanyaloglu, Aylin C. ; Selent, Jana ; Shukla, Arun K. (2020) Distinct phosphorylation sites in a prototypical GPCR differently orchestrate β-arrestin interaction, trafficking, and signaling Science Advances, 6 (37). ISSN 2375-2548 Pandey, Shubhi ; Maharana, Jagannath ; Li, Xaria X. ; Woodruff, Trent M. ; Shukla, Arun K. (2020) Emerging Insights into the Structure and Function of Complement C5a Receptors Trends in Biochemical Sciences, 45 (8). pp. 693-705. ISSN 09680004 Baidya, Mithu ; Kumari, Punita ; Dwivedi-Agnihotri, Hemlata ; Pandey, Shubhi ; Sokrat, Badr ; Sposini, Silvia ; Chaturvedi, Madhu ; Srivastava, Ashish ; Roy, Debarati ; Hanyaloglu, Aylin C. ; Bouvier, Michel ; Shukla, Arun K. (2020) Genetically encoded intrabody sensors report the interaction and trafficking of β-arrestin 1 upon activation of G-protein–coupled receptors Journal of Biological Chemistry, 295 (30). pp. 10153-10167. ISSN 00219258 Saha, Shirsha ; Shukla, Arun K. (2020) The Inside Story: Crystal Structure of the Chemokine Receptor CCR7 with an Intracellular Allosteric Antagonist Biochemistry, 59 (1). pp. 12-14. ISSN 0006-2960 Baidya, Mithu ; Kumari, Punita ; Dwivedi‐Agnihotri, Hemlata ; Pandey, Shubhi ; Chaturvedi, Madhu ; Stepniewski, Tomasz Maciej ; Kawakami, Kouki ; Cao, Yubo ; Laporte, Stéphane A ; Selent, Jana ; Inoue, Asuka ; Shukla, Arun K (2020) Key phosphorylation sites in GPCR s orchestrate the contribution of β‐Arrestin 1 in ERK 1/2 activation EMBO reports, 21 (9). ISSN 1469-221X Lee, Yang ; Warne, Tony ; Nehmé, Rony ; Pandey, Shubhi ; Dwivedi-Agnihotri, Hemlata ; Chaturvedi, Madhu ; Edwards, Patricia C. ; García-Nafría, Javier ; Leslie, Andrew G. W. ; Shukla, Arun K. ; Tate, Christopher G. (2020) Molecular basis of β-arrestin coupling to formoterol-bound β1-adrenoceptor Nature, 583 (7818). pp. 862-866. ISSN 0028-0836 Dwivedi-Agnihotri, Hemlata ; Srivastava, Ashish ; Shukla, Arun K. (2020) Reversible biotinylation of purified proteins for measuring protein–protein interactions Methods Enzymol, 633 . pp. 281-294. ISSN 00766879 Srivastava, Ashish ; Baidya, Mithu ; Dwivedi-Agnihotri, Hemlata ; Shukla, Arun K. (2020) Site-directed labeling of β-arrestin with monobromobimane for measuring their interaction with G protein-coupled receptors Methods in Enzymology, 633 . pp. 271-280. ISSN 00766879 Shukla, Arun K. ; Dwivedi-Agnihotri, Hemlata (2020) Structure and function of β-arrestins, their emerging role in breast cancer, and potential opportunities for therapeutic manipulation Europe PMC Funders Group, 145 . pp. 139-156. ISSN 0065230X Chaturvedi, Madhu ; Maharana, Jagannath ; Shukla, Arun K. (2020) Terminating G-Protein Coupling: Structural Snapshots of GPCR-β-Arrestin Complexes Cell, 180 (6). pp. 1041-1043. ISSN 00928674 Pandey, Shubhi ; Saha, Shirsha ; Shukla, Arun K. (2020) Transmitting the Signal: Structure of the β1-Adrenergic Receptor-Gs Protein Complex Molecular Cell, 80 (1). pp. 3-5. ISSN 10972765 Pandey, Shubhi ; Maharana, Jagannath ; Shukla, Arun K. (2019) The Gut Feeling: GPCRs Enlighten the Way Cell Host & Microbe, 26 (2). pp. 160-162. ISSN 19313128 Ghosh, Eshan ; Dwivedi, Hemlata ; Baidya, Mithu ; Srivastava, Ashish ; Kumari, Punita ; Stepniewski, Tomek ; Kim, Hee Ryung ; Lee, Mi-Hye ; van Gastel, Jaana ; Chaturvedi, Madhu ; Roy, Debarati ; Pandey, Shubhi ; Maharana, Jagannath ; Guixà-González, Ramon ; Luttrell, Louis M. ; Chung, Ka Young ; Dutta, Somnath ; Selent, Jana ; Shukla, Arun K. (2019) Conformational Sensors and Domain Swapping Reveal Structural and Functional Differences between β-Arrestin Isoforms Cell Reports, 28 (13). 3287-3299.e6. ISSN 22111247 Kumari, Punita ; Dwivedi, Hemlata ; Baidya, Mithu ; Shukla, Arun K. (2019) Measuring agonist-induced ERK MAP kinase phosphorylation for G-protein-coupled receptors Methods Cell Biology, 149 . pp. 141-153. ISSN 0091679X Pandey, Shubhi ; Roy, Debarati ; Shukla, Arun K. (2019) Measuring surface expression and endocytosis of GPCRs using whole-cell ELISA Methods Cell Biology, 149 . pp. 131-140. ISSN 0091679X Pandey, Shubhi ; Li, Xaria X. ; Srivastava, Ashish ; Baidya, Mithu ; Kumari, Punita ; Dwivedi, Hemlata ; Chaturvedi, Madhu ; Ghosh, Eshan ; Woodruff, Trent M. ; Shukla, Arun K. (2019) Partial ligand-receptor engagement yields functional bias at the human complement receptor, C5aR1 Journal of Biological Chemistry, 294 (24). pp. 9416-9429. ISSN 00219258 Shukla, Arun K. (2019) Structural Basis of Partial Agonism at the β2-Adrenergic Receptor Biochemistry, 58 (3). pp. 137-139. ISSN 0006-2960 Chaturvedi, Madhu ; Schilling, Justin ; Beautrait, Alexandre ; Bouvier, Michel ; Benovic, Jeffrey L. ; Shukla, Arun K. (2018) Emerging Paradigm of Intracellular Targeting of G Protein-Coupled Receptors Trends in Biochemical Sciences, 43 (7). pp. 533-546. ISSN 09680004 Baidya, Mithu ; Kumari, Punita ; Shukla, Arun K. (2018) Entering the Pocket: Crystal Structure of a Prostaglandin D2 Receptor Molecular Cell, 72 (1). pp. 3-6. ISSN 10972765 Dwivedi, Hemlata ; Baidya, Mithu ; Shukla, Arun K. (2018) GPCR Signaling: The Interplay of Gαi and β-arrestin Current Biology, 28 (7). R324-R327. ISSN 09609822 Safdari, Haaris Ahsan ; Pandey, Shubhi ; Shukla, Arun K. ; Dutta, Somnath (2018) Illuminating GPCR Signaling by Cryo-EM Trends in Cell Biology, 28 (8). pp. 591-594. ISSN 09628924 Sente, Andrija ; Peer, Raphael ; Srivastava, Ashish ; Baidya, Mithu ; Lesk, Arthur M. ; Balaji, Santhanam ; Shukla, Arun K. ; Babu, M. Madan ; Flock, Tilman (2018) Molecular mechanism of modulating arrestin conformation by GPCR phosphorylation Nature Structural & Molecular Biology, 25 (6). pp. 538-545. ISSN 1545-9993 Ranjan, Ravi ; Pandey, Shubhi ; Shukla, Arun K. (2017) Biased Opioid Receptor Ligands: Gain without Pain Trends in Endocrinology & Metabolism, 28 (4). pp. 247-249. ISSN 10432760 Kumari, Punita ; Srivastava, Ashish ; Ghosh, Eshan ; Ranjan, Ravi ; Dogra, Shalini ; Yadav, Prem N. ; Shukla, Arun K. ; York, John (2017) Core engagement with β-arrestin is dispensable for agonist-induced vasopressin receptor endocytosis and ERK activation Molecular Biology of the Cell, 28 (8). pp. 1003-1010. ISSN 1059-1524 Cahill, Thomas J. ; Thomsen, Alex R. B. ; Tarrasch, Jeffrey T. ; Plouffe, Bianca ; Nguyen, Anthony H. ; Yang, Fan ; Huang, Li-Yin ; Kahsai, Alem W. ; Bassoni, Daniel L. ; Gavino, Bryant J. ; Lamerdin, Jane E. ; Triest, Sarah ; Shukla, Arun K. ; Berger, Benjamin ; Little, John ; Antar, Albert ; Blanc, Adi ; Qu, Chang-Xiu ; Chen, Xin ; Kawakami, Kouki ; Inoue, Asuka ; Aoki, Junken ; Steyaert, Jan ; Sun, Jin-Peng ; Bouvier, Michel ; Skiniotis, Georgios ; Lefkowitz, Robert J. (2017) Distinct conformations of GPCR–β-arrestin complexes mediate desensitization, signaling, and endocytosis Proceedings of the National Academy of Sciences, 114 (10). pp. 2562-2567. ISSN 0027-8424 Baidya, Mithu ; Dwivedi, Hemlata ; Shukla, Arun K (2017) Frozen in action: cryo-EM structure of a GPCR–G-protein complex Nature Structural & Molecular Biology, 24 (6). pp. 500-502. ISSN 1545-9993 Ranjan, Ravi ; Dwivedi, Hemlata ; Baidya, Mithu ; Kumar, Mohit ; Shukla, Arun K. (2017) Novel Structural Insights into GPCR–β-Arrestin Interaction and Signaling Trends in Cell Biology, 27 (11). pp. 851-862. ISSN 09628924 Ghosh, Eshan ; Srivastava, Ashish ; Baidya, Mithu ; Kumari, Punita ; Dwivedi, Hemlata ; Nidhi, Kumari ; Ranjan, Ravi ; Dogra, Shalini ; Koide, Akiko ; Yadav, Prem N. ; Sidhu, Sachdev S. ; Koide, Shohei ; Shukla, Arun K. (2017) A synthetic intrabody-based selective and generic inhibitor of GPCR endocytosis Nature Nanotechnology, 12 (12). pp. 1190-1198. ISSN 1748-3387 Kumari, Punita ; Srivastava, Ashish ; Banerjee, Ramanuj ; Ghosh, Eshan ; Gupta, Pragya ; Ranjan, Ravi ; Chen, Xin ; Gupta, Bhagyashri ; Gupta, Charu ; Jaiman, Deepika ; Shukla, Arun K. (2016) Functional competence of a partially engaged GPCR–β-arrestin complex Nature Communications, 7 (1). ISSN 2041-1723 Ranjan, Ravi ; Gupta, Pragya ; Shukla, Arun K. (2016) GPCR Signaling: β-arrestins Kiss and Remember Current Biology, 26 (7). R285-R288. ISSN 09609822 Thomsen, Alex R.B. ; Plouffe, Bianca ; Cahill, Thomas J. ; Shukla, Arun K. ; Tarrasch, Jeffrey T. ; Dosey, Annie M. ; Kahsai, Alem W. ; Strachan, Ryan T. ; Pani, Biswaranjan ; Mahoney, Jacob P. ; Huang, Liyin ; Breton, Billy ; Heydenreich, Franziska M. ; Sunahara, Roger K. ; Skiniotis, Georgios ; Bouvier, Michel ; Lefkowitz, Robert J. (2016) GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling Cell, 166 (4). pp. 907-919. ISSN 00928674 Shukla, Arun K. ; Gupta, Charu ; Srivastava, Ashish ; Jaiman, Deepika (2015) Antibody Fragments for Stabilization and Crystallization of G Protein-Coupled Receptors and Their Signaling Complexes Methods Enzymol, 557 . pp. 247-258. ISSN 00766879 Kumari, Punita ; Ghosh, Eshan ; Shukla, Arun K. (2015) Emerging Approaches to GPCR Ligand Screening for Drug Discovery Trends in Molecular Medicine, 21 (11). pp. 687-701. ISSN 14714914 Srivastava, Ashish ; Gupta, Bhagyashri ; Gupta, Charu ; Shukla, Arun K. (2015) Emerging Functional Divergence of β-Arrestin Isoforms in GPCR Function Trends in Endocrinology & Metabolism, 26 (11). pp. 628-642. ISSN 10432760 Shukla, Arun K. ; Kumari, Punita ; Ghosh, Eshan ; Nidhi, Kumari (2015) From Recombinant Expression to Crystals Methods Enzymol, 556 . pp. 549-561. ISSN 00766879 Ghosh, Eshan ; Kumari, Punita ; Jaiman, Deepika ; Shukla, Arun K. (2015) Methodological advances: the unsung heroes of the GPCR structural revolution Nature Reviews Molecular Cell Biology, 16 (2). pp. 69-81. ISSN 1471-0072 Shukla, Arun K. (2014) Biasing GPCR Signaling from Inside Science Signaling, 7 (310). ISSN 1945-0877 Shukla, Arun K. ; Singh, Garima ; Ghosh, Eshan (2014) Emerging structural insights into biased GPCR signaling Trends in Biochemical Sciences, 39 (12). pp. 594-602. ISSN 09680004 Ghosh, Eshan ; Nidhi, Kumari ; Shukla, Arun K. (2014) SnapShot: GPCR-Ligand Interactions Cell, 159 (7). 1712-1712.e1. ISSN 00928674 Shukla, Arun K. ; Westfield, Gerwin H. ; Xiao, Kunhong ; Reis, Rosana I. ; Huang, Li-Yin ; Tripathi-Shukla, Prachi ; Qian, Jiang ; Li, Sheng ; Blanc, Adi ; Oleskie, Austin N. ; Dosey, Anne M. ; Su, Min ; Liang, Cui-Rong ; Gu, Ling-Ling ; Shan, Jin-Ming ; Chen, Xin ; Hanna, Rachel ; Choi, Minjung ; Yao, Xiao Jie ; Klink, Bjoern U. ; Kahsai, Alem W. ; Sidhu, Sachdev S. ; Koide, Shohei ; Penczek, Pawel A. ; Kossiakoff, Anthony A. ; Woods Jr, Virgil L. ; Kobilka, Brian K. ; Skiniotis, Georgios ; Lefkowitz, Robert J. (2014) Visualization of arrestin recruitment by a G-protein-coupled receptor Nature, 512 (7513). pp. 218-222. ISSN 0028-0836 Aristotelous, Tonia ; Ahn, Seungkirl ; Shukla, Arun K. ; Gawron, Sylwia ; Sassano, Maria F. ; Kahsai, Alem W. ; Wingler, Laura M. ; Zhu, Xiao ; Tripathi-Shukla, Prachi ; Huang, Xi-Ping ; Riley, Jennifer ; Besnard, Jérémy ; Read, Kevin D. ; Roth, Bryan L. ; Gilbert, Ian H. ; Hopkins, Andrew L. ; Lefkowitz, Robert J. ; Navratilova, Iva (2013) Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor ACS Medicinal Chemistry Letters, 4 (10). pp. 1005-1010. ISSN 1948-5875 Shukla, Arun K. ; Manglik, Aashish ; Kruse, Andrew C. ; Xiao, Kunhong ; Reis, Rosana I. ; Tseng, Wei-Chou ; Staus, Dean P. ; Hilger, Daniel ; Uysal, Serdar ; Huang, Li-Yin ; Paduch, Marcin ; Tripathi-Shukla, Prachi ; Koide, Akiko ; Koide, Shohei ; Weis, William I. ; Kossiakoff, Anthony A. ; Kobilka, Brian K. ; Lefkowitz, Robert J. (2013) Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide Nature, 497 (7447). pp. 137-141. ISSN 0028-0836 Reiter, Eric ; Ahn, Seungkirl ; Shukla, Arun K. ; Lefkowitz, Robert J. (2012) Molecular Mechanism of β-Arrestin-Biased Agonism at Seven-Transmembrane Receptors Annual Review of Pharmacology and Toxicology, 52 (1). pp. 179-197. ISSN 0362-1642 Shukla, Arun K. ; Xiao, Kunhong ; Lefkowitz, Robert J. (2011) Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling Trends in Biochemical Sciences, 36 (9). pp. 457-469. ISSN 09680004 Nobles, Kelly N. ; Xiao, Kunhong ; Ahn, Seungkirl ; Shukla, Arun K. ; Lam, Christopher M. ; Rajagopal, Sudarshan ; Strachan, Ryan T. ; Huang, Teng-Yi ; Bressler, Erin A. ; Hara, Makoto R. ; Shenoy, Sudha K. ; Gygi, Steven P. ; Lefkowitz, Robert J. (2011) Distinct Phosphorylation Sites on the β 2 -Adrenergic Receptor Establish a Barcode That Encodes Differential Functions of β-Arrestin Science Signaling, 4 (185). ISSN 1945-0877 Kahsai, Alem W ; Xiao, Kunhong ; Rajagopal, Sudarshan ; Ahn, Seungkirl ; Shukla, Arun K ; Sun, Jinpeng ; Oas, Terrence G ; Lefkowitz, Robert J (2011) Multiple ligand-specific conformations of the β2-adrenergic receptor Nature Chemical Biology, 7 (10). pp. 692-700. ISSN 1552-4450 Shukla, Arun K. ; Kim, Jihee ; Ahn, Seungkirl ; Xiao, Kunhong ; Shenoy, Sudha K. ; Liedtke, Wolfgang ; Lefkowitz, Robert J. (2010) Arresting a Transient Receptor Potential (TRP) Channel Journal of Biological Chemistry, 285 (39). pp. 30115-30125. ISSN 00219258 (In Press) Mangmool, Supachoke ; Shukla, Arun K. ; Rockman, Howard A. (2010) β-Arrestin–dependent activation of Ca2+/calmodulin kinase II after β1–adrenergic receptor stimulation Journal of Cell Biology, 189 (3). pp. 573-587. ISSN 0021-9525 Xiao, Kunhong ; Sun, Jinpeng ; Kim, Jihee ; Rajagopal, Sudarshan ; Zhai, Bo ; Villén, Judit ; Haas, Wilhelm ; Kovacs, Jeffrey J. ; Shukla, Arun K. ; Hara, Makoto R. ; Hernandez, Marylens ; Lachmann, Alexander ; Zhao, Shan ; Lin, Yuan ; Cheng, Yishan ; Mizuno, Kensaku ; Ma'ayan, Avi ; Gygi, Steven P. ; Lefkowitz, Robert J. (2010) Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR) Proceedings of the National Academy of Sciences, 107 (34). pp. 15299-15304. ISSN 0027-8424 Shenoy, Sudha K. ; Modi, Aalok S. ; Shukla, Arun K. ; Xiao, Kunhong ; Berthouze, Magali ; Ahn, Seungkirl ; Wilkinson, Keith D. ; Miller, William E. ; Lefkowitz, Robert J. (2009) β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2 Proceedings of the National Academy of Sciences, 106 (16). pp. 6650-6655. ISSN 0027-8424 Walters, Robert W. ; Shukla, Arun K. ; Kovacs, Jeffrey J. ; Violin, Jonathan D. ; DeWire, Scott M. ; Lam, Christopher M. ; Chen, J. Ruthie ; Muehlbauer, Michael J. ; Whalen, Erin J. ; Lefkowitz, Robert J. (2009) β-Arrestin1 mediates nicotinic acid–induced flushing, but not its antilipolytic effect, in mice Journal of Clinical Investigation, 119 (5). pp. 1312-1321. ISSN 0021-9738 Shukla, Arun K. ; Sun, Jin-Peng ; Lefkowitz, Robert J. (2008) Crystallizing Thinking about the β2-Adrenergic Receptor Molecular Pharmacology, 73 (5). pp. 1333-1338. ISSN 0026-895X Shukla, Arun K. ; Violin, Jonathan D. ; Whalen, Erin J. ; Gesty-Palmer, Diane ; Shenoy, Sudha K. ; Lefkowitz, Robert J. (2008) Distinct conformational changes in β-arrestin report biased agonism at seven-transmembrane receptors Proceedings of the National Academy of Sciences, 105 (29). pp. 9988-9993. ISSN 0027-8424 Lopez, Jakob J. ; Shukla, Arun K. ; Reinhart, Christoph ; Schwalbe, Harald ; Michel, Hartmut ; Glaubitz, Clemens (2008) The Structure of the Neuropeptide Bradykinin Bound to the Human G-Protein Coupled Receptor Bradykinin B2 as Determined by Solid-State NMR Spectroscopy Angewandte Chemie International Edition, 47 (9). pp. 1668-1671. ISSN 14337851 Lefkowitz, Robert J ; Sun, Jin-Peng ; Shukla, Arun K (2008) A crystal clear view of the β2-adrenergic receptor Nature Biotechnology, 26 (2). pp. 189-191. ISSN 1087-0156 Roy, Ankita ; Shukla, Arun Kumar ; Haase, Winfried ; Michel, Hartmut (2007) Employing Rhodobacter sphaeroides to functionally express and purify human G protein-coupled receptors bchm, 389 (1). pp. 69-78. ISSN 1431-6730 Xiao, Kunhong ; McClatchy, Daniel B. ; Shukla, Arun K. ; Zhao, Yang ; Chen, Minyong ; Shenoy, Sudha K. ; Yates, John R. ; Lefkowitz, Robert J. (2007) Functional specialization of β-arrestin interactions revealed by proteomic analysis Proceedings of the National Academy of Sciences, 104 (29). pp. 12011-12016. ISSN 0027-8424 Shukla, Arun Kumar ; Haase, Winfried ; Reinhart, Christoph ; Michel, Hartmut (2007) Heterologous expression and characterization of the recombinant bradykinin B2 receptor using the methylotrophic yeast Pichia pastoris Protein Expression and Purification, 55 (1). pp. 1-8. ISSN 10465928 Shukla, Arun Kumar ; Haase, Winfried ; Reinhart, Christoph ; Michel, Hartmut (2007) Heterologous expression and comparative characterization of the human neuromedin U subtype II receptor using the methylotrophic yeast Pichia pastoris and mammalian cells The International Journal of Biochemistry & Cell Biology, 39 (5). pp. 931-942. ISSN 13572725 Shenoy, Sudha K. ; Barak, Larry S. ; Xiao, Kunhong ; Ahn, Seungkirl ; Berthouze, Magali ; Shukla, Arun K. ; Luttrell, Louis M. ; Lefkowitz, Robert J. (2007) Ubiquitination of β-Arrestin Links Seven-transmembrane Receptor Endocytosis and ERK Activation Journal of Biological Chemistry, 282 (40). pp. 29549-29562. ISSN 00219258 Shukla, Arun Kumar ; Haase, Winfred ; Reinhart, Christoph ; Michel, Hartmut (2006) Biochemical and pharmacological characterization of the human bradykinin subtype 2 receptor produced in mammalian cells using the Semliki Forest virus system Biological Chemistry, 387 (5). ISSN 1431-6730 Shukla, Arun Kumar ; Reinhart, Christoph ; Michel, Hartmut (2006) Comparative analysis of the human angiotensin II type 1a receptor heterologously produced in insect cells and mammalian cells Biochemical and Biophysical Research Communications, 349 (1). pp. 6-14. ISSN 0006291X Shukla, Arun Kumar ; Reinhart, Christoph ; Michel, Hartmut (2006) Dimethylsulphoxide as a tool to increase functional expression of heterologously produced GPCRs in mammalian cells FEBS Letters, 580 (17). pp. 4261-4265. ISSN 00145793 Shukla, Arun Kumar ; Haase, Winfried ; Reinhart, Christoph ; Michel, Hartmut (2006) Functional overexpression and characterization of human bradykinin subtype 2 receptor in insect cells using the baculovirus system Journal of Cellular Biochemistry, 99 (3). pp. 868-877. ISSN 0730-2312 Shukla, Arun K. ; Roy, Kunal B. (2006) A Palindromic Repeat Sequence Adopts a Stable Fold Back Structure under Supercoiling The Journal of Biochemistry, 139 (1). pp. 35-39. ISSN 0021-924X Shukla, Arun Kumar ; Roy, Kunal B. (2006) Rec A-independent homologous recombination induced by a putative fold-back tetraplex DNA Biological Chemistry, 387 (3). pp. 251-256. ISSN 1431-6730 |