Illuminating GPCR Signaling by Cryo-EM

Safdari, Haaris Ahsan ; Pandey, Shubhi ; Shukla, Arun K. ; Dutta, Somnath (2018) Illuminating GPCR Signaling by Cryo-EM Trends in Cell Biology, 28 (8). pp. 591-594. ISSN 09628924

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Official URL: http://doi.org/10.1016/j.tcb.2018.06.002

Related URL: http://dx.doi.org/10.1016/j.tcb.2018.06.002

Abstract

The wave of resolution revolution in cryo-EM has touched, and made a significant impact on, the structural biology of GPCRs. High-resolution structures of several GPCR-G-protein complexes are now determined by cryo-EM and they illuminate fine structural details of this central macromolecular complex involved in cellular signaling.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Ltd.
Keywords:GPCR; arrestins; biased signaling; cryo-EM; negative-staining
ID Code:126429
Deposited On:13 Oct 2022 06:06
Last Modified:13 Oct 2022 06:06

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