Ranjan, Ravi ; Pandey, Shubhi ; Shukla, Arun K. (2017) Biased Opioid Receptor Ligands: Gain without Pain Trends in Endocrinology & Metabolism, 28 (4). pp. 247-249. ISSN 10432760
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Official URL: http://doi.org/10.1016/j.tem.2017.01.001
Related URL: http://dx.doi.org/10.1016/j.tem.2017.01.001
Abstract
Kappa opioid receptor (κ-OR) agonists are promising therapeutic candidates for pain and itch; however, they also exhibit the adverse effects of sedation and dysphoria. A recent study has demonstrated that a G protein-biased agonist for κ-OR provides effective pain and itch relief without causing sedation or dysphoria, in animal models.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Ltd. |
| ID Code: | 126445 |
| Deposited On: | 13 Oct 2022 06:06 |
| Last Modified: | 13 Oct 2022 06:06 |
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