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Number of items: 44.

Purushothaman, D. ; Marcel, N. ; Garg, M. ; Venkataraman, R. ; Sarin, A. (2013) Apoptotic programs are determined during lineage commitment of CD4+ T effectors: selective regulation of T effector-memory apoptosis by inducible nitric oxide synthase The Journal of Immunology, 190 (1). pp. 97-105. ISSN 0022-1767

Gupta, Soumya ; Marcel, Nimi ; Sarin, Apurva ; Shivashankar, G. V. (2012) Role of actin dependent nuclear deformation in regulating early gene expression PLoS One, 7 (12). e53031_1-e53031_9. ISSN 1932-6203

Perumalsamy, L. R. ; Marcel, N. ; Kulkarni, S. ; Radtke, F. ; Sarin, A. (2012) Distinct spatial and molecular features of notch pathway assembly in regulatory T cells Science Signaling, 5 (234). ra53. ISSN 1937-9145

Gupta, Soumya ; Marcel, Nimi ; Talwar, Shefali ; Garg, Megha ; R., Indulaxmi ; Perumalsamy, Lakshmi R. ; Sarin, Apurva ; Shivashankar, G. V. (2012) Developmental heterogeneity in DNA packaging patterns influences T-cell activation and transmigration PLoS One, 7 (9). e43718. ISSN 1932-6203

Perumalsamy, Lakshmi R. ; Nagala, Manjula ; Sarin, Apurva (2010) Notch-activated signaling cascade interacts with mitochondrial remodeling proteins to regulate cell survival PNAS, 107 (15). pp. 6882-6887. ISSN 0027-8424

Purushothaman, Divya ; Sarin, Apurva (2009) Cytokine-dependent regulation of NADPH oxidase activity and the consequences for activated T cell homeostasis Journal of Experimental Medicine, 206 (7). pp. 1515-1523. ISSN 0022-1007

Perumalsamy, L. R. ; Nagala, M. ; Banerjee, P. ; Sarin, A. (2009) A hierarchical cascade activated by non-canonical Notch signaling and the mTOR-Rictor complex regulates neglect-induced death in mammalian cells Cell Death and Differentiation, 16 . pp. 879-889. ISSN 1350-9047

Rao, Jyothsna ; Bhattacharya, Dipanjan ; Banerjee, Bidisha ; Sarin, Apurva ; Shivashankar, G. V. (2007) Trichostatin-A induces differential changes in histone protein dynamics and expression in HeLa cells Biochemical and Biophysical Research Communications, 363 (2). pp. 263-268. ISSN 0006-291X

Srivastava, Smita ; Banerjee, Hridesh ; Chaudhry, Ashutosh ; Khare, Anupriya ; Sarin, Apurva ; George, Anna ; Bal, Vineeta ; Durdik, Jeannine M. ; Rath, Satyajit (2007) Apoptosis-inducing factor regulates death in peripheral T cells The Journal of Immunology, 179 (2). pp. 797-803. ISSN 0022-1767

Goyal, Gaurav ; Fell, Brennan ; Sarin, Apurva ; Youle, Richard J. ; Sriram, V. (2007) Role of mitochondrial remodeling in programmed cell death in Drosophila melanogaster Developmental Cell, 12 (5). pp. 807-816. ISSN 1534-5807

Parikh, Neha ; Koshy, Caroline ; Dhayabaran, Vaigundan ; Perumalsamy, Lakshmi R. ; Sowdhamini, R. ; Sarin, Apurva (2007) The N-terminus and alpha-5, alpha-6 helices of the pro-apoptotic protein Bax, modulate functional interactions with the anti-apoptotic protein Bcl-xL BMC Cell Biology, 8 (1). 16_1-16_16. ISSN 1471-2121

Bheeshmachar, Geetha ; Purushotaman, Divya ; Sade, Hadassah ; Gunasekharan, Vigneshkumar ; Rangarajan, Annapoorni ; Sarin, Apurva (2006) Evidence for a role for notch signaling in the cytokine-dependent survival of activated T cells The Journal of Immunology, 177 (8). pp. 5041-5050. ISSN 0022-1767

Parikh, Neha ; Sade, Hadassah ; Kurian, Leo ; Sarin, Apurva (2004) The bax N terminus is required for negative regulation by the mitogen-activated protein kinase kinase and akt signaling pathways in T cells The Journal of Immunology, 173 (10). pp. 6220-6227. ISSN 0022-1767

Sade, Hadassah ; Krishna, Sudhir ; Sarin, Apurva (2004) The anti-apoptotic effect of Notch-1 requires p56lck-dependent, Akt/PKB-mediated signaling in T cells Journal of Biological Chemistry, 279 (4). pp. 2937-3944. ISSN 0021-9258

Sen, Anindya ; Kuruvilla, Daniel ; Pinto, Ludwin ; Sarin, Apurva ; Rodrigues, Veronica (2004) Programmed cell death and context dependent activation of the EGF pathway regulate gliogenesis in the Drosophila olfactory system Mechanisms of Development, 121 (1). pp. 65-78. ISSN 0925-4773

Sade, Hadassah ; Khandre, Nagamani S. ; Mathew, M. K. ; Sarin, Apurva (2004) The mitochondrial phase of the glucocorticoid-induced apoptotic response in thymocytes comprises sequential activation of adenine nucleotide transporter (ANT)-independent and ANT-dependent events European Journal of Immunology, 34 (1). pp. 119-125. ISSN 0014-2980

Vig, Monika ; Srivastava, Smita ; Kandpal, Usha ; Sade, Hadassah ; Lewis, Virginia ; Sarin, Apurva ; George, Anna ; Bal, Vineeta ; Durdik, Jeannine M. ; Rath, Satyajit (2004) Inducible nitric oxide synthase in T cells regulates T cell death and immune memory Journal of Clinical Investigation, 113 (12). pp. 1734-1742. ISSN 0021-9738

Sade, H. ; Sarin, A. (2004) Reactive oxygen species regulate quiescent T-cell apoptosis via the BH3-only pro-apoptotic protein BIM Cell Death and Differentiation, 11 . pp. 416-423. ISSN 1350-9047

Godbole, A. ; Varghese, J. ; Sarin, A. ; Mathew, M. K. (2003) VDAC is a conserved element of death pathways in plant and animal systems Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1642 (1-2). pp. 87-96. ISSN 0167-4889

Sade, Hadassah ; Sarin, Apurva (2003) IL-7 inhibits dexamethasone-induced apoptosis via Akt/PKB in mature, peripheral T cells European Journal of Immunology, 33 (4). pp. 913-919. ISSN 0014-2980

Varghese, J. ; Khandre, N. S. ; Sarin, A. (2003) Caspase-3 activation is an early event and initiates apoptotic damage in a human leukemia cell line Apoptosis, 8 (4). pp. 363-370. ISSN 1360-8185

Varghese, Jishy ; Sade, Hadassah ; Vandenabeele, Peter ; Sarin, Apurva (2002) Head involution defective (Hid)-triggered apoptosis requires caspase-8 but not FADD (Fas-associated death domain) and is regulated by Erk in mammalian cells Journal of Biological Chemistry, 277 (38). pp. 35197-35104. ISSN 0021-9258

Rangarajan, Annapoorni ; Syal, Ruchi ; Selvarajah, Suganya ; Chakrabarti, Oishee ; Sarin, Apurva ; Krishna, Sudhir (2001) Activated Notch1 signaling co-operates with Papillomavirus oncogenes in transformation and generates resistance to apoptosis on matrix withdrawal through PKB/Akt Virology, 286 (1). pp. 23-30. ISSN 0042-6822

Varghese, Jishy ; Chattopadhaya, Souvik ; Sarin, Apurva (2001) Inhibition of p38 kinase reveals a TNF-α-mediated, caspase-dependent, apoptotic death pathway in a human myelomonocyte cell line The Journal of Immunology, 166 (11). pp. 6570-6577. ISSN 0022-1767

Nandi, Dipankar ; Sarin, Apurva (2001) Trends in basic immunology research - 2001 and beyond Current Science, 80 (5). pp. 647-652. ISSN 0011-3891

Alexander-Miller, Martha A. ; Derby, Michael A. ; Sarin, Apurva ; Henkart, Pierre A. ; Berzofsky, Jay A. (1998) Supraoptimal peptide-major histocompatibility complex causes a decrease in Bcl-2 levels and allows tumor necrosis factor α receptor II-mediated apoptosis of cytotoxic T lymphocytes Journal of Experimental Medicine, 188 (8). pp. 1391-1399. ISSN 0022-1007

Sarin, Apurva ; Haddad, Elias K. ; Henkart, Pierre A. (1998) Caspase dependence of target cell damage induced by cytotoxic lymphocytes The Journal of Immunology, 161 (6). pp. 2810-2816. ISSN 0022-1767

Punt, Jennifer A. ; Havran, Wendy ; Abe, Ryo ; Sarin, Apurva ; Singer, Alfred (1997) T cell receptor (TCR)-induced death of immature CD4+CD8+ thymocytes by two distinct mechanisms differing in their requirement for CD28 costimulation: implications for negative selection in the thymus Journal of Experimental Medicine, 186 (11). pp. 1911-1922. ISSN 0022-1007

Noguchi, Masayuki ; Sarin, Apurva ; Javad Aman, M. ; Nakajima, Hiroshi ; Shores, Elizabeth W. ; Henkart, Pierre A. ; Leonard, Warren J. (1997) Functional cleavage of the common cytokine receptor γ chain (γc) by calpain PNAS, 94 (21). pp. 11534-11539. ISSN 0027-8424

Henkart, Pierre A. ; Williams, Mark S. ; Zacharchuk, Charles M. ; Sarin, Apurva (1997) Do CTL kill target cells by inducing apoptosis? Seminars in Immunology, 9 (2). pp. 135-144. ISSN 1044-5323

Vergelli, M. ; Hemmer, B. ; Muraro, P. A. ; Tranquill, L. ; Biddison, W. E. ; Sarin, A. ; McFarland, H. F. ; Martin, R. (1997) Human autoreactive CD4+ T cell clones use perforin-or Fas/Fas ligand-mediated pathways for target cell lysis The Journal of Immunology, 158 (6). pp. 2756-2761. ISSN 0022-1767

Sarin, Apurva ; Williams, Mark S. ; Alexander-Miller, Martha A. ; Berzofsky, Jay A. ; Zacharchuk, Charles M. ; Henkart, Pierre A. (1997) Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases Immunity, 6 (2). pp. 209-215. ISSN 1074-7613

Sarin, Apurva ; Wu, Ming-Lei ; Henkart, Pierre A. (1996) Different interleukin-1β converting enzyme (ICE) family protease requirements for the apoptotic death of T lymphocytes triggered by diverse stimuli Journal of Experimental Medicine, 184 (6). pp. 2445-2450. ISSN 0022-1007

Alexander-Miller, M. A. ; Leggatt, G. R. ; Sarin, A. ; Berzofsky, J. A. (1996) Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL Journal of Experimental Medicine, 184 (2). pp. 485-492. ISSN 0022-1007

Sarin, A. ; Conan-Cibotti, M. ; Henkart, P. A. (1995) Cytotoxic effect of TNF and lymphotoxin on T lymphoblasts The Journal of Immunology, 155 (8). pp. 3716-3718. ISSN 0022-1767

Sarin, A. ; Saxena, Q. B. ; Herberman, R. B. ; Saxena, R. K. (1995) Enhanced MHC I antigen expression on tumour target cells is inversely correlated to lysis by allogenic but not by xenogenic NK cells Journal of Biosciences, 20 (4). pp. 515-523. ISSN 0250-5991

Sarin, A. ; Nakajima, H. ; Henkart, P. A. (1995) A protease-dependent TCR-induced death pathway in mature lymphocytes The Journal of Immunology, 154 (11). pp. 5806-5812. ISSN 0022-1767

Clerici, M. ; Sarin, A. ; Coffman, R. L. ; Wynn, T. A. ; Blatt, S. P. ; Hendrix, C. W. ; Wolf, S. F. ; Shearer, G. M. ; Henkart, P. A. (1994) Type 1/type 2 cytokine modulation of T-cell programmed cell death as a model for human immunodeficiency virus pathogenesis PNAS, 91 (25). pp. 11811-11815. ISSN 0027-8424

Sarin, A. ; Clerici, M. ; Blatt, S. P. ; Hendrix, C. W. ; Shearer, G. M. ; Henkart, P. A. (1994) Inhibition of activation-induced programmed cell death and restoration of defective immune responses of HIV+ donors by cysteine protease inhibitors The Journal of Immunology, 153 (2). pp. 862-872. ISSN 0022-1767

Sarin, Apurva ; Adams, David H. ; Henkart, Pierre A. (1993) Protease inhibitors selectively block T cell receptor-triggered programmed cell death in a murine T cell hybridoma and activated peripheral T cells. Journal of Experimental Medicine, 178 (5). pp. 1693-1700. ISSN 0022-1007

Sarin, Apurva ; Haridas, Valsala ; Saxena, R. K. (1993) MHC class I up-regulation protects some but not all targets against LAK-mediated lysis: possible implications for the existence of LAK cell subpopulations using different recognition strategies Immunology Letters, 38 (1). pp. 59-62. ISSN 0165-2478

Prabhu, Anila ; Sarin, Apurva ; Saxena, Rajiv K. (1993) B-cell mitogenic effect of dinitrophenyl derivative of Mycobacterium tuberculosis antigens Cellular Immunology, 149 (2). pp. 422-432. ISSN 0008-8749

Sarin, Apurva ; Saxena, Rajiv K. (1990) Necessity for interaction between adherent and non-adherent rat spleen cells for the generation of a suppressor factor of NK activation Immunology Letters, 24 (2). pp. 93-96. ISSN 0165-2478

Sarin, Apurva ; Adler, William H. ; Saxena, Rajiv K. (1989) Lack of optimal activation of natural killer levels by interleukin-2 in rat spleen cells: evidence for suppression Cellular Immunology, 122 (2). pp. 548-554. ISSN 0008-8749

This list was generated on Wed Nov 14 22:09:29 2018 UTC.