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Goyal, Aneesh ; Verma, Priyanka ; Anandhakrishnan, Madhankumar ; Gokhale, Rajesh S. (2012) Molecular basis of the functional divergence of fatty acyl-AMP ligase biosynthetic enzymes of Mycobacterium tuberculosis Journal of Molecular Biology, 416 (2). pp. 221-238. ISSN 0022-2836

Singh, Archana ; Sharma, Pankaj ; Kar, Hemanta K. ; Sharma, Vinod K. ; Tembhre, Manoj K. ; Gupta, Somesh ; Laddha, Naresh C. ; Dwivedi, Mitesh ; Begum, Rasheedunnisa ; Gokhale, Rajesh S. ; Rani, Rajni ; Indian Genome, Variation Consortium (2012) HLA alleles and amino-acid signatures of the peptide-binding pockets of HLA molecules in vitiligo Journal of Investigative Dermatology, 132 . pp. 124-134. ISSN 0022-202X

Mohanty, Debasisa ; Sankaranarayanan, Rajan ; Gokhale, Rajesh S. (2011) Fatty acyl-AMP ligases and polyketide synthases are unique enzymes of lipid biosynthetic machinery in Mycobacterium tuberculosis Tuberculosis, 91 (5). pp. 448-455. ISSN 1472-9792

Gokhale, Rajesh S. (2011) Tuberculosis research: staying ahead of the game Tuberculosis, 91 (5). p. 406. ISSN 1472-9792

Nair, Divya R. ; Ghosh, Ratna ; Manocha, Alzu ; Mohanty, Debasisa ; Saran, Shweta ; Gokhale, Rajesh S. (2011) Two functionally distinctive phosphopantetheinyl transferases from amoeba Dictyostelium discoideum PLos One, 6 (9). pp. 1-10. ISSN 1932-6203

Natarajan, Vivek T. ; Singh, Archana ; Kumar, Avinash A. ; Sharma, Pankaj ; Kar, Hemanta K. ; Marrot, Laurent ; Meunier, Jean-Roch ; Natarajan, Krishnamurthy ; Rani, Rajni ; Gokhale, Rajesh S. (2010) Transcriptional upregulation of Nrf2-dependent phase II detoxification genes in the involved epidermis of vitiligo vulgaris Journal of Investigative Dermatology . ISSN 0022-202X

Khurana, Pankaj ; Gokhale, Rajesh S. ; Mohanty, Debasisa (2010) Genome scale prediction of substrate specificity for acyl adenylate superfamily of enzymes based on active site residue profiles BMC Bioinformatics, 11 . No pp. given. ISSN 1471-2105

Yadav, Gitanjali ; Gokhale, Rajesh S. ; Mohanty, Debasisa (2009) Towards prediction of metabolic products of polyketide synthases: an in silico analysis PLoS Computational Biology, 5 (4). e1000351_1-e1000351_14. ISSN 1553-734X

Arora, Pooja ; Goyal, Aneesh ; Natarajan, Vivek T. ; Rajakumara, Eerappa ; Verma, Priyanka ; Gupta, Radhika ; Yousuf, Malikmohamed ; Trivedi, Omita A. ; Mohanty, Debasisa ; Tyagi, Anil ; Sankaranarayanan, Rajan ; Gokhale, Rajesh S. (2009) Mechanistic and functional insights into fatty acid activation in Mycobacterium tuberculosis Nature Chemical Biology, 5 . pp. 166-173. ISSN 1548-7091

Chopra, Tarun ; Gokhale, Rajesh S. (2009) Polyketide versatility in the biosynthesis of complex mycobacterial cell wall lipids Methods in Enzymology, 459 . pp. 259-294. ISSN 0076-6879

Ansari, Mohd Zeeshan ; Sharma, Jyoti ; Gokhale, Rajesh S. ; Mohanty, Debasisa (2008) In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites BMC Bioinformatics, 9 . No pp. given. ISSN 1471-2105

Chopra, Tarun ; Banerjee, Srijita ; Gupta, Sarika ; Yadav, Gitanjali ; Anand, Swadha ; Surolia, Avadhesha ; Roy, Rajendra P. ; Mohanty, Debasisa ; Gokhale, Rajesh S. (2008) Novel intermolecular iterative mechanism for biosynthesis of mycoketide catalyzed by a bimodular polyketide synthase PLoS Computational Biology, 6 (7). pp. 1584-1598. ISSN 1553-734X

Goyal, Aneesh ; Saxena, Priti ; Rahman, Ataur ; Singh, Parmit Kumar ; Kasbekar, Durgadas P. ; Gokhale, Rajesh S. ; Sankaranarayanan, Rajan (2008) Structural insights into biosynthesis of resorcinolic lipids by a type III polyketide synthase in Neurospora crassa Journal of Structural Biology, 162 (3). pp. 411-421. ISSN 1047-8477

Ghosh, Ratna ; Chhabra, Arush ; Phatale, Pallavi A. ; Samrat, Subodh K. ; Sharma, Jyoti ; Gosain, Anuradha ; Mohanty, Debasisa ; Saran, Shweta ; Gokhale, Rajesh S. (2008) Dissecting the functional role of polyketide synthases in Dictyostelium discoideum Journal of Biological Chemistry, 283 (17). pp. 11348-11354. ISSN 0021-9258

Biet, Franck ; Bay, Sylvie ; Thibault, Virginie C. ; Euphrasie, Daniel ; Grayon, Maggy ; Ganneau, Christelle ; Lanotte, Philippe ; Daffe, Mamadou ; Gokhale, Rajesh ; Etienne, Gilles ; Reyrat, Jean-Marc (2008) Lipopentapeptide induces a strong host humoral response and distinguishes Mycobacterium avium subsp. paratuberculosis from M. avium subsp. avium Vaccine, 26 (2). pp. 257-268. ISSN 0264-410X

Gokhale, Rajesh S. ; Sankaranarayanan, Rajan ; Mohanty, Debasisa (2007) Versatility of polyketide synthases in generating metabolic diversity Current Opinion in Structural Biology, 17 (6). pp. 736-743. ISSN 0959-440X

Gokhale, Rajesh S. ; Saxena, Priti ; Chopra, Tarun ; Mohanty, Debasisa (2007) Versatile polyketide enzymatic machinery for the biosynthesis of complex mycobacterial lipids Natural Product Reports, 24 . pp. 267-277. ISSN 0265-0568

Goyal, Aneesh ; Yousuf, Malikmohamed ; Arora, Pooja ; Gokhale, Rajesh S. ; Rajakumara, Eerappa ; Sankaranarayanan, Rajan (2006) Crystallization and preliminary X-ray crystallographic studies of the N-terminal domain of FadD28, a fatty-acyl AMP ligase from Mycobacterium tuberculosis Acta Crystallographica Section F, 62 (4). pp. 350-352. ISSN 1744-3091

Krithika, R. ; Marathe, Uttara ; Saxena, Priti ; Ansari, Mohd. Zeeshan ; Mohanty, Debasisa ; Gokhale, Rajesh S. (2006) A genetic locus required for iron acquisition in Mycobacterium tuberculosis Proceedings of the National Academy of Sciences of the United States of America, 103 (7). pp. 2069-2074. ISSN 0027-8424

Pearce, Michael J. ; Arora, Pooja ; Festa, Richard A. ; Butler-Wu, Susan M. ; Gokhale, Rajesh S. ; Heran Darwin, K. (2006) Identification of substrates of the Mycobacterium tuberculosis proteasome The EMBO Journal, 25 . pp. 5423-5432. ISSN 0261-4189

Dhawan, Jyotsna ; Gokhale, Rajesh S. ; Verma, Inder M. (2005) Bioscience in India: times are changing Cell, 123 (5). pp. 743-745. ISSN 0092-8674

Arora, Pooja ; Vats, Archana ; Saxena, Priti ; Mohanty, Debasisa ; Gokhale, Rajesh S. (2005) Promiscuous fatty acyl CoA ligases produce acyl-CoA and acyl-SNAC precursors for polyketide biosynthesis Journal of the American Chemical Society, 127 (26). pp. 9388-9389. ISSN 0002-7863

Trivedi, Omita A. ; Arora, Pooja ; Vats, Archana ; Ansari, Mohd. Zeeshan ; Tickoo, Rashmi ; Sridharan, Vijayalakshmi ; Mohanty, Debasisa ; Gokhale, Rajesh S. (2005) Dissecting the mechanism and assembly of a complex virulence mycobacterial lipid Molecular Cell, 17 (5). pp. 631-643. ISSN 1097-2765

Kamra, Pankaj ; Gokhale, Rajesh S. ; Mohanty, Debasisa (2005) SEARCHGTr: a program for analysis of glycosyltransferases involved in glycosylation of secondary metabolites Nucleic Acids Research, 33 (Suppl.). W220-W225. ISSN 0305-1048

Rukmini, R. ; Shanmugam, V. M. ; Saxena, P. ; Gokhale, R. S. ; Sankaranarayanan, R. (2004) Crystallization and preliminary X-ray crystallographic investigations of an unusual type III polyketide synthase PKS18 from Mycobacterium tuberculosis Acta Crystallographica Section D: Biological Crystallography, 60 . pp. 749-751. ISSN 0907-4449

Trivedi, Omita A. ; Arora, Pooja ; Sridharan, Vijayalakshmi ; Tickoo, Rashmi ; Mohanty, Debasisa ; Gokhale, Rajesh S. (2004) Enzymic activation and transfer of fatty acids as acyl-adenylates in mycobacteria Nature, 428 . pp. 441-445. ISSN 0028-0836

Ansari, Mohd. Zeeshan ; Yadav, Gitanjali ; Gokhale, Rajesh S. ; Mohanty, Debasisa (2004) NRPS-PKS: a knowledge-based resource for analysis of NRPS/PKS megasynthases Nucleic Acids Research, 32 (Suppl.). W405-W413. ISSN 0305-1048

Krishnamoorthy, K. ; Gokhale, Rajesh S. ; Contractor, Aliasgar Q. ; Kumar, Anil (2004) Novel label-free DNA sensors based on poly (3, 4-ethylenedioxythiophene) Chemical Communications . pp. 820-821. ISSN 1359-7345

Sankaranarayanan, Rajan ; Saxena, Priti ; Marathe, Uttara B. ; Gokhale, Rajesh S. ; Shanmugam, Vellaiah M. ; Rukmini, Raju (2004) A novel tunnel in mycobacterial type III polyketide synthase reveals the structural basis for generating diverse metabolites Nature Structural & Molecular Biology, 11 . pp. 894-900. ISSN 1545-9993

Saxena, Priti ; Yadav, Gitanjali ; Mohanty, Debasisa ; Gokhale, Rajesh S. (2003) A new family of type III polyketide synthases in Mycobacterium tuberculosis Journal of Biological Chemistry, 278 . pp. 44780-44790. ISSN 0021-9258

Yadav, Gitanjali ; Gokhale, Rajesh S. ; Mohanty, Debasisa (2003) Computational approach for prediction of domain organization and substrate specificity of modular polyketide synthases Journal of Molecular Biology, 328 (2). pp. 335-363. ISSN 0022-2836

Yadav, Gitanjali ; Gokhale, Rajesh S. ; Mohanty, Debasisa (2003) SEARCHPKS: a program for detection and analysis of polyketide synthase domains Nucleic Acids Research, 31 (13). pp. 3654-3658. ISSN 0305-1048

Tsai, Shiou-Chuan ; Miercke, Larry J. W. ; Krucinski, Jolanta ; Gokhale, Rajesh ; Chen, Julian C.-H. ; Foster, Paul G. ; Cane, David E. ; Khosla, Chaitan ; Stroud, Robert M. (2001) Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: versatility from a unique substrate channel PNAS, 98 (26). pp. 14808-14813. ISSN 0027-8424

Yin, Yifeng ; Gokhale, Rajesh ; Khosla, Chaitan ; Cane, David E. (2001) Erythromycin biosynthesis. The 4-pro-S hydride of NADPH is utilized for ketoreduction by both module 5 and module 6 of the 6-deoxyerythronolide B synthase Bioorganic & Medicinal Chemistry Letters, 11 (12). pp. 1477-1479. ISSN 0960-894X

Gokhale, Rajesh S. ; Khosla, Chaitan (2000) Role of linkers in communication between protein modules Current Opinion in Chemical Biology, 4 (1). pp. 22-27. ISSN 1367-5931

Khosla, Chaitan ; Gokhale, Rajesh S. ; Jacobsen, John R. ; Cane, David E. (1999) Tolerance and specificity of polyketide synthases Annual Review of Biochemistry, 68 . pp. 219-253. ISSN 0066-4154

Gokhale, Rajesh S. ; Tsuji, Stuart Y. ; Cane, David E. ; Khosla, Chaitan (1999) Dissecting and exploiting intermodular communication in polyketide synthases Science, 284 (5413). pp. 482-485. ISSN 0036-8075

Gokhale, Rajesh S. ; Hunziker, Daniel ; Cane, David E. ; Khosla, Chaitan (1999) Mechanism and specificity of the terminal thioesterase domain from the erythromycin polyketide synthase Chemistry & Biology, 6 (2). pp. 117-125. ISSN 1074-5521

Gokhale, Rajesh S. ; Ray, Soumya S. ; Balaram, Hemalatha ; Balaram, P. (1999) Unfolding of Plasmodium falciparum triosephosphate isomerase in urea and guanidinium chloride: evidence for a novel disulfide exchange reaction in a covalently cross-linked mutant Biochemistry, 38 (1). pp. 423-431. ISSN 0006-2960

Gopal, B. ; Ray, Soumya S. ; Gokhale, R. S. ; Balaram, H. ; Murthy, M. R. N. ; Balaram, P. (1998) Cavity-creating mutation at the dimer interface of Plasmodium falciparum triosephosphate isomerase: restoration of stability by disulfide cross-linking of subunits Biochemistry, 38 (1). pp. 478-486. ISSN 0006-2960

Pohl, Nicola L. ; Gokhale, Rajesh S. ; Cane, David E. ; Khosla, Chaitan (1998) Synthesis and incorporation of an N-acetylcysteamine analogue of methylmalonyl-CoA by a modular polyketide synthase Journal of the American Chemical Society, 120 (43). pp. 11206-11207. ISSN 0002-7863

Gokhale, Rajesh S. ; Lau, Janice ; Cane, David E. ; Khosla, Chaitan (1998) Functional orientation of the acyltransferase domain in a module of the erythromycin polyketide synthase Biochemistry, 37 (8). pp. 2524-2528. ISSN 0006-2960

Velanker, Sameer S. ; Ray, Soumya S. ; Gokhale, Rajesh S. ; Suma S., ; Balaram, Hemalatha ; Balaram, P. ; Murthy, M. R. N. (1997) Triosephosphate isomerase from Plasmodium falciparum: the crystal structure provides insights into antimalarial drug design Structure, 5 (6). pp. 751-761. ISSN 0969-2126

Pieper, Rembert ; Gokhale, Rajesh S. ; Luo, Guanglin ; Cane, David E. ; Khosla, Chaitan (1997) Purification and characterization of bimodular and trimodular derivatives of the erythromycin polyketide synthase Biochemistry, 36 (7). pp. 1846-1851. ISSN 0006-2960

Agarwalla, Sanjay ; Gokhale, Rajesh S. ; Balaram, P. ; Santi, Daniel V. (1996) Covalent tethering of the dimer interface annuls aggregation in thymidylate synthase Protein Science, 5 (2). pp. 270-277. ISSN 0961-8368

Gokhale, Rajesh S. ; Agarwalla, Sanjay ; Santi, Daniel V. ; Balaram, Padmanabhan (1996) Covalent reinforcement of a fragile region in the dimeric enzyme thymidylate synthase stabilizes the protein against chaotrope-induced unfolding Biochemistry, 35 (22). pp. 7150-7158. ISSN 0006-2960

Gokhale, Rajesh S. ; Agarwalla, Sanjay ; Francis, V. S. ; Santi, Daniel V. ; Balaram, P. (1994) Thermal stabilization of thymidylate synthase by engineering two disulfide bridges across the dimer interface Journal of Molecular Biology, 235 (1). pp. 89-94. ISSN 0022-2836

Punekar, N. S. ; Gokhale, R. S. (1991) Factors influencing the stability of heme and ferrochelatase: role of oxygen Biotechnology and Applied Biochemistry, 14 (1). pp. 21-29. ISSN 0885-4513