Genetic mechanisms underlying the pathogenesis of tropical calcific pancreatitis

Mahurkar, Swapna ; Reddy, D Nageshwar ; Rao, G Venkat ; Chandak, Giriraj Ratan (2009) Genetic mechanisms underlying the pathogenesis of tropical calcific pancreatitis World Journal of Gastroenterology, 15 (3). p. 264. ISSN 1007-9327

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Official URL: http://doi.org/10.3748/wjg.15.264

Related URL: http://dx.doi.org/10.3748/wjg.15.264

Abstract

Chronic pancreatitis is known to be a heterogeneous disease with varied etiologies. Tropical calcific pancreatitis (TCP) is a severe form of chronic pancreatitis unique to developing countries. With growing evidence of genetic factors contributing to the pathogenesis of TCP, this review is aimed at compiling the available information in this field. We also propose a two hit model to explain the sequence of events in the pathogenesis of TCP.

Item Type:Article
Source:Copyright of this article belongs to Baishideng Publishing Group Inc.
Keywords:Chronic Pancreatitis; Tropical Calcific Pancreatitis; Fibrocalculous Pancreatic Diabetes; Complex Disease; Candidate Gene Analysis.
ID Code:116969
Deposited On:15 Apr 2021 06:03
Last Modified:07 Feb 2023 04:16

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