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Number of items: 103.

Bharti, Sanjay Kumar ; Rex, Kervin ; Sreedhar, Pujari ; Krishnan, Neeraja ; Varshney, Umesh (2011) Chimeras of Escherichia coli and Mycobacterium tuberculosis single-stranded DNA binding proteins: characterization and function in Escherichia coli PLos One, 6 (12). e27216_1-e27216_13. ISSN 1932-6203

Kurthkotia, Krishna ; Varshney, Umesh (2011) Distinct mechanisms of DNA repair in mycobacteria and their implications in attenuation of the pathogen growth Mechanism of Ageing and Development, 91 . pp. 533-543. ISSN 0047-6374

Kapoor, Suman ; Samhita, Laasya ; Varshney, Umesh (2011) Functional significance of an evolutionarily conserved Alanine (GCA) resume codon in tmRNA in Escherichia coli Journal of Bacteriology, 193 (14). pp. 3569-3576. ISSN 0021-9193

Kumar, Pradeep ; Bharti, Sanjay Kumar ; Varshney, Umesh (2011) Uracil excision repair in Mycobacterium tuberculosis cell-free extracts Tuberculosis, 91 (3). pp. 212-218. ISSN 1472-9792

Kurthkoti, Krishna ; Varshney, Umesh (2011) Base excision and nucleotide excision repair pathways in mycobacteria Tuberculosis . No pp. given.. ISSN 1472-9792

Kurthkoti, Krishna ; Varshney, Umesh (2010) Detrimental effects of hypoxia-specific expression of uracil DNA glycosylase (Ung) in Mycobacterium smegmatis Journal of Bacteriology, 192 (24). pp. 6439-6446. ISSN 0021-9193

Seshadri, Anuradha ; Sadananda Singh, N. ; Varshney, Umesh (2010) Recycling of the posttermination complexes of mycobacterium smegmatis and Escherichia coli ribosomes using heterologous factors Journal of Molecular Biology, 401 (5). pp. 854-865. ISSN 0022-2836

Kapoor, Suman ; Das, Gautam ; Varshney, Umesh (2010) Crucial contribution of the multiple copies of the initiator tRNA genes in the fidelity of tRNAfMet selection on the ribosomal P-site in Escherichia coli Nucleic Acids Research, 39 (1). pp. 202-212. ISSN 0305-1048

Kaushal, Prem Singh ; Talawar, Ramappa K. ; Varshney, Umesh ; Vijayan, M. (2010) Structure of uracil-DNA glycosylase from Mycobacterium tuberculosis: insights into interactions with ligands Acta Crystallographica Section F, 66 (8). pp. 887-892. ISSN 1744-3091

Malshetty, Vidyasagar ; Kurthkoti, Krishna ; China, Arnab ; Mallick, Bratati ; Yamunadevi, Subburaj ; Sang, Pau Biak ; Srinivasan, Narayanaswamy ; Nagaraja, Valakunja ; Varshney, Umesh (2010) Novel insertion and deletion mutants of RpoB that render mycobacterium smegmatis RNA polymerase resistant to rifampicin-mediated inhibition of transcription Microbiology, 156 (5). pp. 1565-1573. ISSN 1350-0872

Malshetty, Vidyasagar S. ; Jain, Ruchi ; Srinath, Thiruneelakantan ; Kurthkoti, Krishna ; Varshney, Umesh (2010) Synergistic effects of UdgB and Ung in mutation prevention and protection against commonly encountered DNA damaging agents in Mycobacterium smegmatis Microbiology, 156 (3). pp. 940-949. ISSN 1350-0872

Bharti, Sanjay Kumar ; Varshney, Umesh (2010) Analysis of the impact of a uracil DNA glycosylase attenuated in AP-DNA binding in maintenance of the genomic integrity in Escherichia coli Nucleic Acids Research, 38 (7). pp. 2291-2301. ISSN 0305-1048

Seshadri, Anuradha ; Samhita, Laasya ; Gaur, Rahul ; Malshetty, Vidyasagar ; Varshney, Umesh (2009) Analysis of the fusA2 locus encoding EFG2 in Mycobacterium smegmatis Tuberculosis, 89 (6). pp. 453-464. ISSN 1472-9792

Kurthkoti, Krishna ; Srinath, Thiruneelakantan ; Kumar, Pradeep ; Malshetty, Vidyasagar S. ; Sang, Pau Biak ; Jain, Ruchi ; Manjunath, Ramanathapuram ; Varshney, Umesh (2009) A distinct physiological role of MutY in mutation prevention in mycobacteria Microbiology, 156 (1). pp. 88-93. ISSN 1350-0872

Seshadri, Anuradha ; Dubey, Badrinath ; Weber, Michael H. W. ; Varshney, Umesh (2009) Impact of rRNA methylations on ribosome recycling and fidelity of initiation in Escherichia coli Molecular Microbiology, 72 (3). pp. 795-808. ISSN 0950-382X

Kurthkoti, Krishna ; Kumar, Pradeep ; Jain, Ruchi ; Varshney, Umesh (2008) Important role of the nucleotide excision repair pathway in Mycobacterium smegmatis in conferring protection against commonly encountered DNA-damaging agents Microbiology, 154 (9). pp. 2776-2785. ISSN 1350-0872

Singh, Nongmaithem Sadananda ; Ahmad, Rais ; Sangeetha, Ramachandran ; Varshney, Umesh (2008) Recycling of ribosomal complexes stalled at the step of elongation in Escherichia coli Journal of Molecular Biology, 380 (3). pp. 451-464. ISSN 0022-2836

Kaushal, Prem Singh ; Talawar, Ramappa K. ; Krishna, P. D. V. ; Varshney, Umesh ; Vijayan, M. (2008) Unique features of the structure and interactions of mycobacterial uracil-DNA glycosylase: structure of a complex of the Mycobacterium tuberculosis enzyme in comparison with those from other sources Acta Crystallographica Section D, 64 (5). pp. 551-560. ISSN 0907-4449

Gaur, Rahul ; Grasso, Domenick ; Datta, Partha P. ; Krishna, P. D. V. ; Das, Gautam ; Spencer, Angela ; Agrawal, Rajendra K. ; Spremulli, Linda ; Varshney, Umesh (2008) A single mammalian mitochondrial translation initiation factor functionally replaces two bacterial factors Molecular Cell, 29 (2). pp. 180-190. ISSN 1097-2765

Das, Gautam ; Thotala, Dinesh Kumar ; Kapoor, Suman ; Karunanithi, Sheelarani ; Thakur, Suman S. ; Sadananda Singh, N. ; Varshney, Umesh (2008) Role of 16S ribosomal RNA methylations in translation initiation in Escherichia coli EMBO Journal, 27 . pp. 840-851. ISSN 0261-4189

Jain, Ruchi ; Kumar, Pradeep ; Varshney, Umesh (2007) A distinct role of formamidopyrimidine DNA glycosylase (MutM) in down-regulation of accumulation of G, C mutations and protection against oxidative stress in mycobacteria DNA Repair, 6 (12). pp. 1774-1785. ISSN 1568-7864

Kachroo, Aashiq H. ; Kancherla, Aswani K. ; Singh, Nongmaithem S. ; Varshney, Umesh ; Mahadevan, Subramony (2007) Mutations that alter the regulation of the chb operon of Escherichia coli allow utilization of cellobiose Molecular Microbiology, 66 (6). pp. 1382-1395. ISSN 0950-382X

Srinath, Thiruneelakantan ; Bharti, Sanjay Kumar ; Varshney, Umesh (2007) Substrate specificities and functional characterization of a thermo-tolerant uracil DNA glycosylase (UdgB) from Mycobacterium tuberculosis DNA Repair, 6 (10). pp. 1517-1528. ISSN 1568-7864

Selvaraj, M. ; Roy, Siddhartha ; Singh, N. S. ; Sangeetha, R. ; Varshney, Umesh ; Vijayan, M. (2007) Structural plasticity and enzyme action: crystal structures of Mycobacterium tuberculosis peptidyl-tRNA hydrolase Journal of Molecular Biology, 372 (1). pp. 186-193. ISSN 0022-2836

Gaur, Rahul ; Björk, Glenn R. ; Tuck, Simon ; Varshney, Umesh (2007) Diet-dependent depletion of queuosine in tRNAs in Caenorhabditis elegans does not lead to a developmental block Journal of Biosciences, 32 (4). pp. 747-754. ISSN 0250-5991

Singh, Prem ; Talawar, Ramappa K. ; Krishna, P. D. V. ; Varshney, Umesh ; Vijayan, M. (2006) Overexpression, purification, crystallization and preliminary X-ray analysis of uracil N-glycosylase from Mycobacterium tuberculosis in complex with a proteinaceous inhibitor Acta Crystallographica Section F, 62 (12). pp. 1231-1234. ISSN 1744-3091

Selvaraj, M. ; Singh, N. S. ; Roy, Siddhartha ; Sangeetha, R. ; Varshney, Umesh ; Vijayan, M. (2006) Cloning, expression, purification, crystallization and preliminary X-ray analysis of peptidyl-tRNA hydrolase from Mycobacterium tuberculosis Acta Crystallographica Section F, 62 (9). pp. 913-915. ISSN 1744-3091

Das, Gautam ; Varshney, Umesh (2006) Peptidyl-tRNA hydrolase and its critical role in protein biosynthesis Microbiology, 152 (8). pp. 2191-2195. ISSN 1350-0872

Seshadri, Anuradha ; Varshney, Umesh (2006) Mechanism of recycling of post-termination ribosomal complexes in eubacteria: a new role of initiation factor 3 Journal of Biosciences, 31 (2). pp. 281-289. ISSN 0250-5991

Gaur, Rahul ; Varshney, Umesh (2005) Genetic analysis identifies a function for the queC (ybaX) gene product at an initial step in the queuosine biosynthetic pathway in Escherichia coli Journal of Bacteriology, 187 (20). pp. 6893-6901. ISSN 0021-9193

Das, Gautam ; Dineshkumar, T. K. ; Thanedar, Swapna ; Varshney, Umesh (2005) Acquisition of a stable mutation in metY allows efficient initiation from an amber codon in Escherichia coli Microbiology, 151 (6). pp. 1741-1750. ISSN 1350-0872

Saikrishnan, K. ; Kalapala, S. K. ; Varshney, U. ; Vijayan, M. (2005) X-ray structural studies of Mycobacterium tuberculosis RRF and a comparative study of RRFs of known structure. Molecular plasticity and biological implications Journal of Molecular Biology, 345 (1). pp. 29-38. ISSN 0022-2836

Saikrishnan, K. ; Kalapala, S. K. ; Varshney, U. ; Vijayan, M. (2005) X-ray structural studies of Mycobacterium tuberculosis RRF and a comparative study of RRFs of known structures. Molecular plasticity and biological implications Journal of Molecular Biology, 345 (1). pp. 29-38. ISSN 0022-2836

Singh, N. S. ; Das, G. ; Seshadri, A. ; Sangeetha, R. ; Varshney, U. (2005) Evidence for a role of initiation factor 3 in recycling of ribosomal complexes stalled on mRNAs in Escherichia coli Nucleic Acids Research, 33 (17). pp. 5591-5601. ISSN 0305-1048

Kumar, Pradeep ; Krishna, Kurthkoti ; Srinivasan, Ramanujam ; Ajitkumar, Parthasarathi ; Varshney, Umesh (2004) Mycobacterium tuberculosis and Escherichia coli nucleoside diphosphate kinases lack multifunctional activities to process uracil containing DNA DNA Repair, 3 (11). pp. 1483-1492. ISSN 1568-7864

Acharya, Narottam ; Talawar, Ramappa K. ; Purnapatre, Kedar ; Varshney, Umesh (2004) Use of sequence microdivergence in mycobacterial ortholog to analyze contributions of the water-activating loop histidine of Escherichia coli uracil-DNA glycosylase in reactant binding and catalysis Biochemical and Biophysical Research Communications, 320 (3). pp. 893-899. ISSN 0006-291X

Saikrishnan, K. ; Kalapala, S. K. ; Bidya Sagar, M. ; Rao, A. R. ; Varshney, U. ; Vijayan, M. (2004) Purification, crystallization and preliminary X-ray studies of Mycobacterium tuberculosis RRF Acta Crystallographica Section D, 60 . pp. 368-370. ISSN 0907-4449

Varshney, U. ; Ramesh, V. ; Madabushi, A. ; Gaur, R. ; Subramanya, H. S. ; RajBhandary, U. L. (2004) Mycobacterium tuberculosis Rv2118c codes for a single-component homotetrameric m1A58 tRNA methyltransferase Nucleic Acids Research, 32 (3). pp. 1018-1027. ISSN 0305-1048

Singh, Nongmaithem Sadananda ; Varshney, Umesh (2004) A physiological connection between tmRNA and peptidyl-tRNA hydrolase functions in Escherichia coli Nucleic Acids Research, 32 (20). pp. 6028-6037. ISSN 0305-1048

Saikrishnan, K. ; Jeyakanthan, J. ; Venkatesh, J. ; Acharya, N. ; Sekar, K. ; Varshney, U. ; Vijayan, M. (2003) Structure of Mycobacterium tuberculosis single-stranded DNA-binding protein. Variability in quaternary structure and its implications Journal of Molecular Biology, 331 (2). pp. 385-393. ISSN 0022-2836

Venkatesh, Jeganathan ; Kumar, Pradeep ; Krishna, Pulukuri Sai Murali ; Manjunath, Ramanathapuram ; Varshney, Umesh (2003) Importance of uracil DNA glycosylase in Pseudomonas aeruginosa and Mycobacterium smegmatis, G+C-rich bacteria, in mutation prevention, tolerance to acidified nitrite, and endurance in mouse macrophages The Journal of Biological Chemistry, 278 (27). pp. 24350-24358. ISSN 0021-9258

Acharya, Narottam ; Kumar, Pradeep ; Varshney, Umesh (2003) Complexes of the uracil-DNA glycosylase inhibitor protein, Ugi, with Mycobacterium smegmatis and Mycobacterium tuberculosis uracil-DNA glycosylases Microbiology, 149 (7). pp. 1647-1658. ISSN 1350-0872

Stortchevoi, Alexei ; Varshney, Umesh ; RajBhandary, Uttam L. (2003) Common location of determinants in initiator transfer RNAs for initiator-elongator discrimination in bacteria and in eukaryotes The Journal of Biological Chemistry, 278 (20). pp. 17672-17679. ISSN 0021-9258

Acharya, Narottam ; Talawar, Ramappa K. ; Saikrishnan, K. ; Vijayan, M. ; Varshney, Umesh (2003) Substitutions at tyrosine 66 of Escherichia coli uracil DNA glycosylase lead to characterization of an efficient enzyme that is recalcitrant to product inhibition Nucleic Acids Research, 31 (24). pp. 7216-7226. ISSN 0305-1048

Rao, Arasada Rajeswara ; Varshney, Umesh (2002) Characterization of Mycobacterium tuberculosis ribosome recycling factor (RRF) and a mutant lacking six amino acids from the C-terminal end reveals that the C-terminal residues are important for its occupancy on the ribosome Microbiology, 148 (12). pp. 3913-3920. ISSN 1350-0872

Dineshkumar, T. K. ; Thanedar, Swapna ; Subbulakshmi, C. ; Varshney, Umesh (2002) An unexpected absence of queuosine modification in the tRNAs of an Escherichia coli B strain Microbiology, 148 (12). pp. 3779-3787. ISSN 1350-0872

Thomas, Mini ; Varshney, Umesh ; Bhattacharya, Santanu (2002) Distamycin analogues without leading amide at their N-termini - comparative binding properties to AT- and GC-rich DNA sequences European Journal of Organic Chemistry, 2002 (21). pp. 3604-3615. ISSN 1434-193X

Handa, Priya ; Acharya, Narottam ; Talawar, Ramappa K. ; Roy, Sudipta ; Varshney, Umesh (2002) Contrasting effects of mutating active site residues, Aspartic acid 64 and Histidine 187 of Escherichia coli uracil-DNA glycosylase on uracil excision and interaction with an inhibitor protein Indian Journal of Biochemistry & Biophysics, 39 . pp. 312-317. ISSN 0301-1208

Acharya, Narottam ; Roy, Sudipta ; Varshney, Umesh (2002) Mutational analysis of the uracil DNA glycosylase inhibitor protein and its interaction with Escherichia coli uracil DNA glycosylase Journal of Molecular Biology, 321 (4). pp. 579-590. ISSN 0022-2836

Saikrishnan, K. ; Bidya Sagar, M. ; Ravishankar, R. ; Roy, S. ; Purnapatre, K. ; Handa, P. ; Varshney, U. ; Vijayan, M. (2002) Domain closure and action of uracil DNA glycosylase (UDG): structures of new crystal forms containing the Escherichia coli enzyme and a comparative study of the known structures involving UDG Acta Crystallographica Section D, 58 . pp. 1269-1276. ISSN 0907-4449

Vijayan, M. ; Jeyakanthan, J. ; Venkatesh, J. ; Acharya, N. ; Sekar, K. ; Varshney, U. ; Saikrishnan, K. (2002) The crystal structure of the single-stranded DNA-binding protein from Mycobacterium tuberculosis Acta Crystallographica Section A, 58 (Suppl.). c275-c275. ISSN 0108-7673

Acharya, Narottam ; Varshney, Umesh (2002) Biochemical properties of single-stranded DNA-binding protein from Mycobacterium smegmatis, a fast-growing Mycobacterium and its physical and functional interaction with uracil DNA glycosylases Journal of Molecular Biology, 318 (5). pp. 1251-1264. ISSN 0022-2836

Ghosh, Mahua ; Rumpal, Nidhi ; Varshney, Umesh ; Chary, Kandala V. R. (2002) Structural basis for poor uracil excision from hairpin DNA European Journal of Biochemistry, 269 (7). pp. 1886-1894. ISSN 0014-2956

Saikrishnan, K. ; Jeyakanthan, J. ; Venkatesh, J. ; Acharya, N. ; Purnapatre, K. ; Sekar, K. ; Varshney, U. ; Vijayan, M. (2002) Crystallization and preliminary X-ray studies of the single-stranded DNA-binding protein from Mycobacterium tuberculosis Acta Crystallographica Section D, 58 . pp. 327-329. ISSN 0907-4449

Dastur, Anahita ; Kumar, Pradeep ; Ramesh, Sneha ; Vasanthakrishna, Mundodi ; Varshney, Umesh (2002) Analysis of the initiator tRNA genes from a slow-and a fast-growing mycobacterium Archives of Microbiology, 178 (4). pp. 288-296. ISSN 0302-8933

Handa, Priya ; Acharya, Narottam ; Varshney, Umesh (2002) Effects of mutations at tyrosine 66 and asparagine 123 in the active site pocket of Escherichia coli uracil DNA glycosylase on uracil excision from synthetic DNA oligomers: evidence for the occurrence of long-range interactions between the enzyme and substrate Nucleic Acids Research, 30 (14). pp. 3086-3095. ISSN 0305-1048

Handa, Priya ; Thanedar, Swapna ; Varshney, Umesh (2002) Rapid and reliable site-directed mutagenesis using Kunkel's approach Methods in Molecular Biology, 182 (1). pp. 1-6. ISSN 1064-3745

Köhrer, Caroline ; Xie, Liang ; Kellerer, Susanne ; Varshney, Umesh ; RajBhandary, Uttam L. (2001) Import of amber and ochre suppressor tRNAs into mammalian cells: a general approach to site-specific insertion of amino acid analogues into proteins PNAS, 98 (25). pp. 14310-14315. ISSN 0027-8424

Thanedar, Swapna ; Dineshkumar, T. K. ; Varshney, Umesh (2001) The mere lack of rT modification in initiator tRNA does not facilitate formylation-independent initiation in Escherichia coli Journal of Bacteriology, 183 (24). pp. 7397-7402. ISSN 0021-9193

Gupta, Amrita ; Hari Kumar, P. ; Dineshkumar, T. K. ; Varshney, Umesh ; Subramanya, Hosahalli S. (2001) Crystal structure of Rv2118c: an AdoMet-dependent methyltransferase from Mycobacterium tuberculosis H37Rv Journal of Molecular Biology, 312 (2). pp. 381-391. ISSN 0022-2836

Dastur, A. ; Varshney, U. (2001) Promoter analysis in mycobacteria using xyl E reporter assays and its implication in high throughput screening Tuberculosis, 81 (4). pp. 267-269. ISSN 1472-9792

Thomas, M. ; Rao, A. R. ; Varshney, U. ; Bhattacharya, S. (2001) Unusual DNA binding exhibited by synthetic distamycin analogues lacking the N-terminal amide unit under high salt conditions Journal of Biomolecular Structure & Dynamics, 18 (6). pp. 858-871. ISSN 0739-1102

Handa, Priya ; Acharya, Narottam ; Varshney, Umesh (2001) Chimeras between single-stranded DNA-binding proteins from Escherichia coli and Mycobacterium tuberculosis reveal that their C-terminal domains interact with uracil DNA glycosylases The Journal of Biological Chemistry, 276 (20). pp. 16992-16997. ISSN 0021-9258

Handa, Priya ; Roy, Sudipta ; Varshney, Umesh (2001) The role of leucine 191 of Escherichia coli uracil DNA glycosylase in the formation of a highly stable complex with the substrate mimic, ugi, and in uracil excision from the synthetic substrates The Journal of Biological Chemistry, 276 (20). pp. 17324-17331. ISSN 0021-9258

Mayer, C. ; Stortchevoi, A. ; Köhrer, C. ; Varshney, U. ; Rajbhandary, U. L. (2001) Initiator tRNA and its role in initiation of protein synthesis Cold Spring Harbor Symposia on Quantitative Biology, 66 . pp. 195-206. ISSN 0091-7451

Rao, Arasada Rajeswara ; Varshney, Umesh (2001) Specific interaction between the ribosome recycling factor and the elongation factor G from Mycobacterium tuberculosis mediates peptidyl-tRNA release and ribosome recycling in Escherichia coli EMBO Journal, 20 . pp. 2977-2986. ISSN 0261-4189

Thanedar, Swapna ; Vinay Kumar, N. ; Varshney, Umesh (2000) The fate of the initiator tRNAs is sensitive to the critical balance between interacting proteins The Journal of Biological Chemistry, 275 (27). pp. 20361-20367. ISSN 0021-9258

Sivagami, A. V. ; Rajeswara Rao, A. ; Varshney, U. (2000) A simple and cost-effective method for preparing DNA from the hard tooth tissue, and its use in polymerase chain reaction amplification of amelogenin gene segment for sex determination in an Indian population Forensic Science International, 110 (2). pp. 107-115. ISSN 0379-0738

Handa, Priya ; Acharya, Narottam ; Thanedar, Swapna ; Purnapatre, Kedar ; Varshney, Umesh (2000) Distinct properties of Mycobacterium tuberculosis single-stranded DNA binding protein and its functional characterization in Escherichia coli Nucleic Acids Research, 28 (19). pp. 3823-3829. ISSN 0305-1048

Ghosh, Mahua ; Vinay Kumar, N. ; Varshney, Umesh ; Chary, K. V. R. (2000) Structural basis for uracil DNA glycosylase interaction with uracil: NMR study Nucleic Acids Research, 28 (9). pp. 1906-1912. ISSN 0305-1048

Purnapatre, Kedar ; Varshney, Umesh (1999) Cloning, over-expression and biochemical characterization of the single-stranded DNA binding protein from Mycobacterium tuberculosis European Journal of Biochemistry, 264 (2). pp. 591-598. ISSN 0014-2956

Bhanuprakash Reddy, G. ; Purnapatre, Kedar ; Lawrence, Rajendran ; Roy, Sudipta ; Varshney, Umesh ; Surolia, Avadhesha (1999) Linear free-energy model description of the conformational stability of uracil-DNA glycosylase inhibitor European Journal of Biochemistry, 261 (3). pp. 610-617. ISSN 0014-2956

Purnapatre, Kedar ; Handa, Priya ; Venkatesh, Jeganathan ; Varshney, Umesh (1999) Differential effects of single-stranded DNA binding proteins (SSBs) on uracil DNA glycosylases (UDGs) from Escherichia coli and mycobacteria Nucleic Acids Research, 27 (17). pp. 3487-3492. ISSN 0305-1048

Ghosh, Mahua ; Chary, K. V. R. ; Vinay Kumar, N. ; Varshney, Umesh (1999) Structural characterisation of a uracil containing hairpin DNA by NMR and molecular dynamics Nucleic Acids Research, 27 (19). pp. 3938-3944. ISSN 0305-1048

Purnapatre, Kedar ; Varshney, Umesh (1998) Uracil DNA glycosylase from Mycobacterium smegmatis and its distinct biochemical properties European Journal of Biochemistry, 256 (3). pp. 580-588. ISSN 0014-2956

Roy, Sudipta ; Purnapatre, Kedar ; Handa, Priya ; Boyanapalli, Madanamohan ; Varshney, Umesh (1998) Use of a coupled transcriptional system for consistent overexpression and purification of UDG-Ugi complex and Ugi from Escherichia coli Protein Expression and Purification, 13 (2). pp. 155-162. ISSN 1046-5928

Vasanthakrishna, M. ; Rumpal, N. ; Varshney, U. (1998) Organization and copy number of initiator tRNA genes in slow- and fast- growing mycobacteria Journal of Biosciences, 23 (2). pp. 101-110. ISSN 0250-5991

Varshney, U. ; Jahroudi, N. ; van de Sande, J. H. ; Gedamu, L. (1998) Inosine incorporation in GC rich RNA probes increases hybridization sequence specificity Nucleic Acids Research, 16 (9). p. 4162. ISSN 0305-1048

Ravishankar, R. ; Bidya Sagar, M. ; Vijayan, M. ; Roy, S. ; Purnapatre, K. ; Handa, P. ; Varshney, U. (1998) X-ray analysis of a complex of Escherichia coli uracil DNA glycosylase (EcUDG) with a proteinaceous inhibitor: the structure elucidation of a prokaryotic UDG Nucleic Acids Research, 26 (21). pp. 4880-4887. ISSN 0305-1048

Vasanthakrishna, M. ; Vinay Kumar, N. ; Varshney, U. (1997) Characterization of the initiator tRNA gene locus and identification of a strong promoter from Mycobacterium tuberculosis Microbiology, 143 (11). pp. 3591-3598. ISSN 1350-0872

Ramesh, V. ; Varshney, U. ; Rajbhandary, U. L. (1997) Intragenic suppression in tRNA: evidence for crosstalk between the D and the T stems RNA, 3 (11). pp. 1220-1232. ISSN 1355-8382

Vinay Kumar, N. ; Varshney, U. (1997) Contrasting effects of single stranded DNA binding protein on the activity of uracil DNA glycosylase from Escherichia coli towards different DNA substrates Nucleic Acids Research, 25 (12). pp. 2336-2343. ISSN 0305-1048

Mandal, Subhrangsu S. ; Varshney, Umesh ; Bhattacharya, Santanu (1997) Role of the central metal ion and ligand charge in the DNA binding and modification by metallosalen complexes Bioconjugate Chemistry, 8 (6). pp. 798-812. ISSN 1043-1802

Mandal, Subhrangsu S. ; Kumar, N. Vinay ; Varshney, Umesh ; Bhattacharya, Santanu (1996) Metal-ion-dependent oxidative DNA cleavage by transition metal complexes of a new water-soluble salen derivative Journal of Inorganic Biochemistry, 63 (4). pp. 265-272. ISSN 0162-0134

Li, Shihong ; Vinay Kumar, N. ; Varshney, Umesh ; RajBhandary, Uttam L. (1996) Important role of the amino acid attached to tRNA in formylation and in initiation of protein synthesis in Escherichia coli The Journal of Biological Chemistry, 271 (2). pp. 1022-1028. ISSN 0021-9258

Varshney, U. ; Lee, C. P. ; RajBhandary, U. L. (1995) From elongator tRNA to initiator tRNA PNAS, 90 (6). pp. 2305-2309. ISSN 0027-8424

Kumar, N. V. ; Varshney, U. (1994) Excision of uracil from the ends of double stranded DNA by uracil DNA glycosylase and its use in high efficiency cloning of PCR products Current Science, 67 (9-10). pp. 728-734. ISSN 0011-3891

Vinay Kumar, N. ; Varshney, U. (1994) Inefficient excision of uracil from loop regions of DNA oligomers by E.coli uracil DNA glycosylase Nucleic Acids Research, 22 (18). pp. 3737-3741. ISSN 0305-1048

Varshney, U. ; RajBhandary, U. L. (1992) Role of methionine and formylation of initiator tRNA in initiation of protein synthesis in Escherichia coli Journal of Bacteriology, 174 (23). pp. 7819-7826. ISSN 0021-9193

Lee, C. P. ; Dyson, M. R. ; Mandal, N. ; Varshney, U. ; Bahramian, B. ; RajBhandary, U. L. (1992) Striking effects of coupling mutations in the acceptor stem on recognition of tRNAs by Escherichia coli Met-tRNA synthetase and Met-tRNA transformylase PNAS, 89 (19). pp. 9262-9266. ISSN 0027-8424

Varshney, U. ; Lee, C. P. ; RajBhandary, U. L. (1991) Direct analysis of aminoacylation levels of tRNAs in vivo. Application to studying recognition of Escherichia coli initiator tRNA mutants by glutaminyl-tRNA synthetase The Journal of Biological Chemistry, 266 (26). pp. 24712-24718. ISSN 0021-9258

Varshney, U. ; Lee, C. P. ; Seong, B. L. ; RajBhandary, U. L. (1991) Mutants of initiator tRNA that function both as initiators and elongators The Journal of Biological Chemistry, 266 (27). pp. 18018-18024. ISSN 0021-9258

Varshney, Umesh ; van de Sande, Johan H. (1991) Specificities and kinetics of uracil excision from uracil-containing DNA oligomers by Escherichia coli uracil DNA glycosylase Biochemistry, 30 (6). pp. 4055-4061. ISSN 0006-2960

Varshney, U. ; RajBhandary, U. L. (1990) Initiation of protein synthesis from a termination codon PNAS, 87 (4). pp. 1586-1590. ISSN 0027-8424

Varshney, U. ; van de Sande, J. H. (1989) Characterization of the ung1 mutation of Escherichia coli Nucleic Acids Research, 17 (2). p. 813. ISSN 0305-1048

Foster, R. ; Jahroudi, N. ; Varshney, U. ; Gedamu, L. (1988) Structure and expression of the human metallothionein-IG gene. Differential promoter activity of two linked metallothionein-I genes in response to heavy metals The Journal of Biological Chemistry, 263 (23). pp. 11528-11535. ISSN 0021-9258

Varshney, U. ; Hutcheon, T. ; van de Sande, J. H. (1988) Sequence analysis, expression, and conservation of Escherichia coli uracil DNA glycosylase and its gene (ung) The Journal of Biological Chemistry, 263 . pp. 7776-7784. ISSN 0021-9258

Jorgenson, K. F. ; Varshney, U. ; van de Sande, I. H. (1988) Interaction of Hoechst 33258 with repeating synthetic DNA polymers and natural DNA Journal of Biomolecular Structure & Dynamics, 5 (5). pp. 1005-1023. ISSN 0739-1102

Varshney, U. ; Jahroudi, N. ; Foster, R. ; Gedamu, L. (1986) Structure, organization, and regulation of human metallothionein IF gene: differential and cell-type-specific expression in response to heavy metals and glucocorticoids Molecular and Cellular Biology, 6 (1). pp. 26-37. ISSN 0270-7306

Lieberman, H. B. ; Rabin, M. ; Barker, P. E. ; Ruddle, F. H. ; Varshney, U. ; Gedamu, L. (1985) Human metallothionein-II processed gene is located in region p11→q21 of chromosome 4 Cytogenetics and Cell Genetics, 39 (2). pp. 109-115. ISSN 0301-0171

Varshney, Umesh ; Gedamu, Lashitew (1984) Human metallothionein MT-I and MT-II processed genes Gene, 31 (1-3). pp. 135-145. ISSN 0378-1119

Varshney, U. ; Hoar, D. I. ; Starozik, D. ; Gedamu, L. (1984) A frequent restriction fragment length polymorphism in the human metallothionein-II processed gene region is evolutionarily conserved Molecular Biology and Medicine, 2 (3). pp. 193-206. ISSN 0735-1313

Koropatnick, James ; Andrews, Glen ; Duerksen, J. D. ; Varshney, Umesh ; Gedamu, Lashitew (1983) Mouse hepatic metallothionein-1 gene cleavage by micrococcal nuclease is enhanced after induction by cadmium Nucleic Acids Research, 11 (10). pp. 3255-3267. ISSN 0305-1048

This list was generated on Mon Dec 23 09:04:34 2024 UTC.