Browse by Fellow

Vamsee Aditya Mallajosyula, V. ; Citron, Michael ; Ferrara, Francesca ; Temperton, Nigel J. ; Liang, Xiaoping ; Flynn, Jessica A. ; Varadarajan, Raghavan (2015) Hemagglutinin sequence conservation guided stem immunogen design from influenza A H3 subtype Frontiers in Immunology, 6 . Article ID 329. ISSN 1664-3224

Shembekar, Nachiket ; Mallajosyula, Vamsee V. Aditya ; Chaudhary, Piyush ; Upadhyay, Vaibhav ; Varadarajan, Raghavan ; Gupta, Satish Kumar (2014) Humanized antibody neutralizing 2009 pandemic H1N1 virus Biotechnology Journal, 9 (12). pp. 1594-1603. ISSN 1860-6768

Kesavardhana, Sannula ; Varadarajan, Raghavan (2014) Stabilizing the native trimer of HIV-1 Env by destabilizing the heterodimeric interface of the gp41 postfusion six-helix bundle Journal of Virology, 88 (17). pp. 9590-9604. ISSN 0022-538X

Mallajosyula, Vamsee V. A. ; Citron, Michael ; Ferrara, Francesca ; Lu, Xianghan ; Callahan, Cheryl ; Heidecker, Gwendolyn J. ; Sarma, Siddhartha P. ; Flynn, Jessica A. ; Temperton, Nigel J. ; Liang, Xiaoping ; Varadarajan, Raghavan (2014) Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection PNAS, 111 (25). E2514-E2523. ISSN 0027-8424

Tan, Kuan Pern ; Khare, Shruti ; Varadarajan, Raghavan ; Madhusudhan, Mallur Srivatsan (2014) TSpred: a web server for the rational design of temperature-sensitive mutants Nucleic Acids Research, 42 (W1). W277-W284. ISSN 0305-1048

Jain, Pankaj C. ; Varadarajan, Raghavan (2014) A rapid, efficient, and economical inverse polymerase chain reaction-based method for generating a site saturation mutant library Analytical Biochemistry, 449 . pp. 90-98. ISSN 0003-2697

Tripathi, Arti ; Dewan, Pooja C. ; Siddique, Shahbaz A. ; Varadarajan, Raghavan (2014) MazF-induced growth inhibition and persister generation in Escherichia coli Journal of Biological Chemistry, 289 (7). pp. 4191-4205. ISSN 0021-9258

Tripathi, Arti ; Varadarajan, Raghavan (2014) Residue specific contributions to stability and activity inferred from saturation mutagenesis and deep sequencing Current Opinion in Structural Biology, 24 . pp. 63-71. ISSN 0959-440X

Vamsee Aditya Mallajosyula, V. ; Citron, Michael ; Lu, Xianghan ; Meulen, Jan ter ; Varadarajan, Raghavan ; Liang, Xiaoping (2013) In vitro and in vivo characterization of designed immunogens derived from the CD-helix of the stem of influenza hemagglutinin Proteins: Structure, Function, and Bioinformatics, 81 (10). pp. 1759-1775. ISSN 0887-3585

Reichenwallner, Jörg ; Chakour, Mohammed ; Indu, S. ; Varadarajan, Raghavan ; Trommer, Wolfgang E. (2013) Maltose binding protein is partially structured in its molten globule state Applied Magnetic Resonance, 44 (8). pp. 983-995. ISSN 0937-9347

Tan, Kuan Pern ; Nguyen, Thanh Binh ; Patel, Siddharth ; Varadarajan, Raghavan ; Madhusudhan, M. S. (2013) Depth: a web server to compute depth, cavity sizes, detect potential small-molecule ligand-binding cavities and predict the pKa of ionizable residues in proteins Nucleic Acids Research, 41 (W1). W314-W321. ISSN 0305-1048

Singh, Pranveer ; Sharma, Likhesh ; Rajendra Kulothungan, S. ; Adkar, Bharat V. ; Prajapati, Ravindra Singh ; Shaik Syed Ali, P. ; Krishnan, Beena ; Varadarajan, Raghavan (2013) Effect of signal peptide on stability and folding of escherichia coli thioredoxin PLoS One, 8 (5). Article ID e63442. ISSN 1932-6203

Bhattacharyya, Sanchari ; Singh, Pranveer ; Rathore, Ujjwal ; Purwar, Mansi ; Wagner, Denise ; Arendt, Heather ; DeStefano, Joanne ; LaBranche, Celia C. ; Montefiori, David C. ; Phogat, Sanjay ; Varadarajan, Raghavan (2013) Design of an Escherichia coli expressed HIV-1 gp120 fragment immunogen that binds to b12 and induces broad and potent neutralizing antibodies Journal of Biological Chemistry, 288 (14). pp. 9815-9825. ISSN 0021-9258

Bhattacharyya, Sanchari ; Varadarajan, Raghavan (2013) Packing in molten globules and native states Current Opinion in Structural Biology, 23 (1). pp. 11-21. ISSN 0959-440X

Sambhara, Suryaprakash ; Shembekar, Nachiket ; Mallajosyula, Vamsee V. Aditya ; Mishra, Arpita ; Yeolekar, Leena ; Dhere, Rajeev ; Kapre, Subhash ; Varadarajan, Raghavan ; Gupta, Satish Kumar (2013) Isolation of a high affinity neutralizing monoclonal antibody against 2009 pandemic H1N1 virus that binds at the ‘Sa’ antigenic site PLoS One, 8 (1). Article ID e55516. ISSN 1932-6203

Bommakanti, Gayathri ; Lu, Xianghan ; Citron, Michael P. ; Najar, Tariq Ahmad ; Heidecker, Gwendolyn J. ; Meulen, Jan ter ; Varadarajan, Raghavan ; Liang, Xiaoping (2012) Design of E. coli expressed stalk domain immunogens of H1N1 HA that protect mice from lethal challenge Journal of Virology, 86 (24). pp. 13434-13444. ISSN 0022-538X

Gautam, Saurabh ; Dubey, Priyanka ; Singh, Pranveer ; Varadarajan, Raghavan ; Gupta, Munishwar N. (2012) Simultaneous refolding and purification of recombinant proteins by macro-(affinity ligand) facilitated three-phase partitioning Analytical Biochemistry, 430 (1). pp. 56-64. ISSN 0003-2697

Tripathi, Arti ; Dewan, Pooja C. ; Barua, Bipasha ; Varadarajan, Raghavan (2012) Additional role for the ccd operon of F-plasmid as a transmissible persistence factor PNAS, 109 (31). pp. 12497-12502. ISSN 0027-8424

Gautam, Saurabh ; Dubey, Priyanka ; Singh, Pranveer ; Kesavardhana, S. ; Varadarajan, Raghavan ; Gupta, Munishwar N. (2012) Smart polymer mediated purification and recovery of active proteins from inclusion bodies Journal of Chromatography A, 1235 . pp. 10-25. ISSN 0021-9673

Saha, Piyali ; Bhattacharyya, Sanchari ; Kesavardhana, Sannula ; Miranda, Edward Roshan ; Shaik Syed Ali, P. ; Sharma, Deepak ; Varadarajan, Raghavan (2012) Designed cyclic permutants of HIV-1 gp120: implications for envelope trimer structure and immunogen design Biochemistry, 51 (9). pp. 1836-1847. ISSN 0006-2960

Adkar, Bharat V. ; Tripathi, Arti ; Sahoo, Anusmita ; Bajaj, Kanika ; Goswami, Devrishi ; Chakrabarti, Purbani ; Swarnkar, Mohit K. ; Gokhale, Rajesh S. ; Varadarajan, Raghavan (2012) Protein model discrimination using mutational sensitivity derived from deep sequencing Structure, 20 (2). pp. 371-381. ISSN 0969-2126

Haimann, Michaela M. ; Akdogan, Yasar ; Philipp, Reinhard ; Varadarajan, Raghavan ; Hinderberger, Dariush ; Trommer, Wolfgang E. (2011) Conformational changes of the chaperone SecB upon binding to a model substrate – bovine pancreatic trypsin inhibitor (BPTI) Biological Chemistry, 392 (10). No pp. given. ISSN 1431-6730

Aggarwal, Vasudha ; Rajendra Kulothungan, S. ; Balamurali, M. M. ; Saranya, S. R. ; Varadarajan, Raghavan ; Ainavarapu, Sri Rama Koti (2011) Ligand-modulated parallel mechanical unfolding pathways of maltose-binding proteins Journal of Biological Chemistry, 286 . pp. 28056-28065. ISSN 0021-9258

Tan, Kuan Pern ; Varadarajan, Raghavan ; Madhusudhan, M. S. (2011) DEPTH: a web server to compute depth and predict small-molecule binding cavities in proteins Nucleic Acids Research, 39 (S2). W242-W248. ISSN 0305-1048

Aggarwal, Vasudha ; Rajendra Kulothungan, S. ; Rajaram, Saranya ; Balamurali, M. M. ; Varadarajan, Raghavan ; Ainavarapu, Sri Rama Koti (2011) Single-molecule studies of the parallel unfolding pathways of Maltose Binding Protein (MBP) Biophysical Journal, 100 (3). 481a-481a. ISSN 0006-3495

Indu, S. ; Kochat, V. ; Thakurela, S. ; Ramakrishnan, C. ; Varadarajan, Raghavan (2011) Conformational analysis and design of cross-strand disulfides in antiparallel β-sheets Proteins: Structure, Function,and Bioinformatics, 79 (1). pp. 244-260. ISSN 0887-3585

Saha, Piyali ; Barua, Bipasha ; Bhattacharyya, Sanchari ; Balamurali, M. M. ; Schief, William R. ; Baker, David ; Varadarajan, Raghavan (2011) Design and characterization of stabilized derivatives of human CD4D12 and CD4D1 Biochemistry, 50 (37). pp. 7891-7900. ISSN 0006-2960

Aggarwal, Vasudha ; Rajendra Kulothungan, S. ; Balamurali, M. M. ; Saranya, S. R. ; Varadarajan, Raghavan ; Ainavarapu, Sri Rama Koti (2011) Ligand modulated parallel mechanical unfolding pathways of Maltose binding proteins (MBPs) Journal Biological Chemistry, M111 . p. 249045. ISSN 0021-9258

Bhattacharyya, Sanchari ; Rajan, Roshan Elizabeth ; Swarupa, Yalla ; Rathore, Ujjwal ; Verma, Anjali ; Udaykumar, Ranga ; Varadarajan, Raghavan (2010) Design of a non-glycosylated outer domain derived HIV-1 gp120 immunogen that binds to CD4 and induces neutralizing antibodies Journal of Biological Chemistry, 285 . pp. 27100-27110. ISSN 0021-9258

Bommakanti, Gayathri ; Citron, Michael P. ; Hepler, Robert W. ; Callahan, Cheryl ; Heidecker, Gwendolyn J. ; Najar, Tariq Ahmad ; Lu, Xianghan ; Joyce, Joseph G. ; Shiver, John W. ; Casimiro, Danilo R. ; Meulen, Jan ter ; Liang, Xiaoping ; Varadarajan, Raghavan (2010) Design of an HA2-based Escherichia coli expressed influenza immunogen that protects mice from pathogenic challenge PNAS, 107 (31). pp. 13701-13706. ISSN 0027-8424

Indu, S. ; Kumar, Senthil T. ; Thakurela, Sudhir ; Gupta, Mansi ; Bhaskara, Ramachandra M. ; Ramakrishnan, C. ; Varadarajan, Raghavan (2010) Disulfide conformation and design at helix N-termini Proteins: Structure, Function, and Bioinformatics, 78 (5). pp. 1228-1242. ISSN 0887-3585

Bhattacharya, Santanu ; Varadarajan, Raghavan (2010) Emerging trends at the interface of chemistry and biology: applications to the design of human therapeutics Journal of Chemical Sciences, 122 (2). pp. 97-107. ISSN 0253-4134

Rajendra Kulothungan, S. ; Das, Mili ; Johnson, Madrid ; Ganesh, Chandramowli ; Varadarajan, Raghavan (2009) Effect of crowding agents, signal peptide, and chaperone SecB on the folding and aggregation of E. coli Maltose Binding Protein Langmuir, 25 (12). pp. 6637-6648. ISSN 0743-7463

Krishnan, Beena ; Rajendra Kulothungan, S. ; Patra, Ashish K. ; Udgaonkar, Jayant B. ; Varadarajan, Raghavan (2009) SecB-mediated protein export need not occur via kinetic partitioning Journal of Molecular Biology, 385 (4). pp. 1243-1256. ISSN 0022-2836

Bajaj, Kanika ; Dewan, Pooja C. ; Chakrabarti, Purbani ; Goswami, Devrishi ; Barua, Bipasha ; Baliga, Chetana ; Varadarajan, Raghavan (2008) Structural correlates of the temperature sensitive phenotype derived from saturation mutagenesis studies of CcdB Biochemistry, 47 (49). pp. 12964-12973. ISSN 0006-2960

Raghava, Smita ; Barua, Bipasha ; Singh, Pradeep K. ; Das, Mili ; Madan, Lalima ; Bhattacharyya, Sanchari ; Bajaj, Kanika ; Gopal, B. ; Varadarajan, Raghavan ; Gupta, Munishwar N. (2008) Refolding and simultaneous purification by three-phase partitioning of recombinant proteins from inclusion bodies Protein Science, 17 (11). pp. 1987-1997. ISSN 0961-8368

Raghava, Smita ; Aquil, Samina ; Bhattacharyya, Sanchari ; Varadarajan, Raghavan ; Gupta, Munishwar N. (2008) Strategy for purifying maltose binding protein fusion proteins by affinity precipitation Journal of Chromatography A, 1194 (1). pp. 90-95. ISSN 0021-9673

Das, Anindya ; Sood, A. K. ; Maiti, Prabal K. ; Das, Mili ; Varadarajan, R. ; Rao, C. N. R. (2008) Binding of nucleobases with single-walled carbon nanotubes: theory and experiment Chemical Physics Letters, 453 (4-6). pp. 266-273. ISSN 0009-2614

Bajaj, Kanika ; Madhusudhan, M. S. ; Adkar, Bharat V. ; Chakrabarti, Purbani ; Ramakrishnan, C. ; Sali, Andrej ; Varadarajan, Raghavan (2007) Stereochemical criteria for prediction of the effects of proline mutations on protein stability PLoS Computational Biology, 3 (12). e241-e241. ISSN 1553-734X

Das, Mili ; Kobayashi, Masanori ; Yamada, Yusuke ; Sreeramulu, Sridhar ; Ramakrishnan, C. ; Wakatsuki, Soichi ; Kato, Ryuichi ; Varadarajan, Raghavan (2007) Design of disulfide-linked thioredoxin dimers and multimers through analysis of crystal contacts Journal of Molecular Biology, 372 (5). pp. 1278-1292. ISSN 0022-2836

Prajapati, Ravindra Singh ; Indu, S. ; Varadarajan, Raghavan (2007) Identification and thermodynamic characterization of molten globule states of periplasmic binding proteins Biochemistry, 46 (36). pp. 10339-10352. ISSN 0006-2960

Mondal, Kajari ; Dastidar, Antara Ghosh ; Singh, Guramrit ; Madhusudhanan, S. ; Gande, Santosh Lakshmi ; VijayRaghavan, K. ; Varadarajan, Raghavan (2007) Design and isolation of temperature-sensitive mutants of Gal4 in yeast and Drosophila Journal of Molecular Biology, 370 (5). pp. 939-950. ISSN 0022-2836

Mondal, Kalyani ; Raghava, Smita ; Barua, Bipasha ; Varadarajan, Raghavan ; Gupta, Munishwar N. (2007) Role of stimuli-sensitive polymers in protein refolding: α-amylase and CcdB (controller of cell division or death B) as model proteins Langmuir, 23 (1). pp. 70-75. ISSN 0743-7463

Prajapati, Ravindra S. ; Sirajuddin, Minhajuddin ; Durani, Venuka ; Sreeramulu, Sridhar ; Varadarajan, Raghavan (2006) Contribution of cation-π interactions to protein stability Biochemistry, 45 (50). pp. 15000-15010. ISSN 0006-2960

Chakraborty, Kausik ; Durani, Venuka ; Roshan Miranda, Edward ; Citron, Michael ; Liang, Xiaoping ; Schleif, William ; Joyce, Joseph G. ; Varadarajan, Raghavan (2006) Design of immunogens that present the crown of the HIV-1 V3 loop in a conformation competent to generate 447-52D-like antibodies Biochemical Journal, 399 . pp. 483-491. ISSN 0006-2936

Sharma, Deepak ; Balamurali, M. M. ; Chakraborty, Kausik ; Kumaran, Sowmini ; Jeganathan, Sadasivam ; Rashid, Umar ; Ingallinella, Paolo ; Varadarajan, Raghavan (2005) Protein minimization of the gp120 binding region of human CD4 Biochemistry, 44 (49). pp. 16192-16202. ISSN 0006-2960

Bajaj, Kanika ; Chakrabarti, Purbani ; Varadarajan, Raghavan (2005) Mutagenesis-based definitions and probes of residue burial in proteins PNAS, 102 (45). pp. 16221-16226. ISSN 0027-8424

Chakraborty, Kausik ; Thakurela, Sudhir ; Prajapati, Ravindra Singh ; Indu, S. ; Shaik Syed Ali, P. ; Ramakrishnan, C. ; Varadarajan, Raghavan (2005) Protein stabilization by introduction of cross-strand disulfides Biochemistry, 44 (44). pp. 14638-14646. ISSN 0006-2960

Das, Mili ; Vasudeva Rao, Bharathi ; Ghosh, Sanjukta ; Varadarajan, Raghavan (2005) Attempts to delineate the relative contributions of changes in hydrophobicity and packing to changes in stability of ribonuclease S mutants Biochemistry, 44 (15). pp. 5923-5930. ISSN 0006-2960

Varadarajan, Raghavan ; Sharma, Deepak ; Chakraborty, Kausik ; Patel, Mayuri ; Citron, Michael ; Sinha, Prem ; Yadav, Ramkishor ; Rashid, Umar ; Kennedy, Sarah ; Eckert, Debra ; Geleziunas, Romas ; Bramhill, David ; Schleif, William ; Liang, Xiaoping ; Shiver, John (2005) Characterization of gp120 and its single-chain derivatives, gp120-CD4_D12 and gp120-M9: implications for targeting the CD4_i epitope in human immunodeficiency virus vaccine design Journal of Virology, 79 (3). pp. 1713-1723. ISSN 0022-538X

Chakraborty, Kausik ; Shivakumar, P. ; Raghothama, S. ; Varadarajan, Raghavan (2005) NMR structural analysis of a peptide mimic of the bridging sheet of HIV-1 gp120 in methanol and water Biochemical Journal, 390 . pp. 573-581. ISSN 0264-6021

Bhinge, Akshay ; Chakrabarti, Purbani ; Uthanumallian, Kavitha ; Bajaj, Kanika ; Chakraborty, Kausik ; Varadarajan, Raghavan (2004) Accurate detection of protein: ligand binding sites using molecular dynamics simulations Structure, 12 (11). pp. 1989-1999. ISSN 0969-2126

Chakshusmathi, Ghadiyaram ; Mondal, Kajari ; Santosh Lakshmi, G. ; Singh, Guramrit ; Roy, Ankita ; Babu, Ravindra ; Madhusudhanan, S. ; Varadarajan, Raghavan (2004) Design of temperature-sensitive mutants solely from amino acid sequence PNAS, 101 (21). pp. 7925-7930. ISSN 0027-8424

Beena, K. ; Udgaonkar, Jayant B. ; Varadarajan, R. (2004) Effect of signal peptide on the stability and folding kinetics of maltose binding protein Biochemistry, 43 (12). pp. 3608-3619. ISSN 0006-2960

Bajaj, Kanika ; Chakshusmathi, Gadhiyaram ; Bachhawat-Sikder, Kiran ; Surolia, Avadhesha ; Varadarajan, Raghvan (2004) Thermodynamic characterization of monomeric and dimeric forms of CcdB (controller of cell division or death B protein) Biochemical Journal, 380 . pp. 409-417. ISSN 0264-6021

Prajapati, R. S. ; Lingaraju, G. M. ; Bacchawat, Kiran ; Surolia, Avadhesha ; Varadarajan, Raghavan (2003) Thermodynamic effects of replacements of pro residues in helix interiors of maltose-binding protein Proteins: Structure, Function, and Bioinformatics, 53 (4). pp. 863-871. ISSN 0887-3585

Padmakumar, V. C. ; Varadarajan, Raghavan (2003) A gradient PCR-based screen for use in site-directed mutagenesis Analytical Biochemistry, 314 (2). pp. 310-315. ISSN 0003-2697

Chakravarty, Suvobrata ; Bhinge, Akshay ; Varadarajan, Raghavan (2002) A procedure for detection and quantitation of cavity volumes in proteins: application to measure the strength of the hydrophobic driving force in protein folding Journal of Biological Chemistry, 277 (25). pp. 31345-31353. ISSN 0021-9258

Chakravarty, Suvobrata ; Varadarajan, Raghavan (2002) Elucidation of factors responsible for enhanced thermal stability of proteins: a structural genomics based study Biochemistry, 41 (25). pp. 8152-8161. ISSN 0006-2960

Rudresh, ; Jain, Rinku ; Dani, Vardhan ; Mitra, Ashima ; Srivastava, Sarika ; Sarma, Siddhartha P. ; Varadarajan, R. ; Ramakumar, S. (2002) Structural consequences of replacement of an α- helical pro residue in Escherichia coli thioredoxin Protein Engineering, 15 (8). pp. 627-633. ISSN 0269-2139

Panse, Vikram G. ; Beena, K. ; Philipp, Reinhard ; Trommer, Wolfgang E. ; Vogel, Pia D. ; Varadarajan, Raghavan (2001) Electron spin resonance and fluorescence studies of the bound-state conformation of a model protein substrate to the chaperone SecB Journal of Biological Chemistry, 276 (36). pp. 33681-33688. ISSN 0021-9258

Ratnaparkhi, Girish S. ; Varadarajan, Raghavan (2001) Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states Journal of Biological Chemistry, 276 (31). pp. 28789-28798. ISSN 0021-9258

Ganesh, C. ; Zaidi, Faisal N. ; Udgaonkar, Jayant B. ; Varadarajan, Raghavan (2001) Reversible formation of on-pathway macroscopic aggregates during the folding of maltose binding protein Protein Science, 10 (8). pp. 1635-1644. ISSN 0961-8368

Ratnaparkhi, Girish S. ; Awasthi, Satish Kumar ; Rani, P. ; Balaram, P. ; Varadarajan, R. (2000) Structural and thermodynamic consequences of introducing α-aminoisobutyric acid in the S peptide of ribonuclease S Protein Engineering Design & Selection, 13 (10). pp. 697-702. ISSN 1741-0126

Chakravarty, Suvobrata ; Mitra, Nivedita ; Queitsch, Iris ; Surolia, Avadhesha ; Varadarajan, Raghavan ; Dübel, Stefan (2000) Protein stabilization through phage display FEBS Letters, 476 (3). pp. 296-300. ISSN 0014-5793

Panse, Vikram G. ; Vogel, Pia ; Trommer, Wolfgang E. ; Varadarajan, Raghavan (2000) A thermodynamic coupling mechanism for the disaggregation of a model peptide substrate by chaperone SecB Journal of Biological Chemistry, 275 (25). pp. 18698-18703. ISSN 0021-9258

Chakravarty, Suvobrata ; Varadarajan, Raghavan (2000) Elucidation of determinants of protein stability through genome sequence analysis FEBS Letters, 470 (1). pp. 65-69. ISSN 0014-5793

Panse, Vikram G. ; Swaminathan, Chittor P. ; Aloor, Jim Jose ; Surolia, Avadhesha ; Varadarajan, Raghavan (2000) Unfolding thermodynamics of the tetrameric chaperone, SecB Biochemistry, 39 (9). pp. 2362-2369. ISSN 0006-2960

Panse, Vikram G. ; Swaminathan, Chittoor P. ; Surolia, Avadhesha ; Varadarajan, Raghavan (2000) Thermodynamics of substrate binding to the chaperone SecB Biochemistry, 39 (9). pp. 2420-2427. ISSN 0006-2960

Ratnaparkhi, Girish S. ; Varadarajan, R. (2000) Thermodynamic and structural studies of cavity formation in proteins suggest that loss of packing interactions rather than the hydrophobic effect dominates the observed energetics Biochemistry, 39 (40). pp. 12365-12374. ISSN 0006-2960

Ratnaparkhi, Girish S. ; Varadarajan, R. (1999) X-ray crystallographic studies of the denaturation of ribonuclease S Proteins: Structure, Function, and Bioinformatics, 36 (3). pp. 282-294. ISSN 0887-3585

Chakravarty, Suvobrata ; Varadarajan, Raghavan (1999) Residue depth: a novel parameter for the analysis of protein structure and stability Structure, 7 (7). pp. 723-732. ISSN 0969-2126

Ganesh, C. ; Banerjee, Antara ; Shah, Aseema ; Varadarajan, Raghavan (1999) Disordered N-terminal residues affect the folding thermodynamics and kinetics of maltose binding protein FEBS Letters, 454 (3). pp. 307-311. ISSN 0014-5793

Chakshusmathi, G. ; Ratnaparkhi, Girish S. ; Madhu, P. K. ; Varadarajan, R. (1999) Native-state hydrogen-exchange studies of a fragment complex can provide structural information about the isolated fragments PNAS, 96 (14). pp. 7899-7904. ISSN 0027-8424

Sheshadri, S. ; Lingaraju, G. M. ; Varadarajan, R. (1999) Denaturant mediated unfolding of both native and molten globule states of maltose binding protein are accompanied by large ΔC_p's Protein Science, 8 (8). pp. 1689-1695. ISSN 0961-8368

Ghoshal, Alokesh K. ; Swaminathan, Chittoor P. ; Thomas, Celestine J. ; Surolia, Avadhesha ; Varadarajan, Raghavan (1999) Thermodynamic and kinetic analysis of the Escherichia coli thioredoxin-C' fragment complementation system Biochemical Journal, 339 . pp. 721-727. ISSN 0264-6021

Chakrabarti, Atis ; Srivastava, Sarika ; Swaminathan, Chittoor P. ; Surolia, Avadhesha ; Varadarajan, Raghavan (1999) Thermodynamics of replacing an α-helical Pro residue in the P40S mutant of Escherichia coli thioredoxin Protein Science, 8 (11). pp. 2455-2459. ISSN 0961-8368

Panse, Vikram G. ; Udgaonkar, Jayant B. ; Varadarajan, Raghavan (1998) SecB binds only to a late native-like intermediate in the folding pathway of barstar and not to the unfolded state Biochemistry, 37 (41). pp. 14477-14483. ISSN 0006-2960

Ratnaparkhi, Girish S. ; Ramachandran, S. ; Udgaonkar, Jayant B. ; Varadarajan, R. (1998) Discrepancies between the NMR and X-ray structures of uncomplexed barstar: analysis suggests that packing densities of protein structures determined by NMR are unreliable Biochemistry, 37 (19). pp. 6958-6966. ISSN 0006-2960

Ratnaparkhi, Girish S. ; Varadarajan, R. (1997) Structural studies of protein unfolding Current Science, 72 (11). pp. 826-830. ISSN 0011-3891

Ganesh, C. ; Shah, Aseema N. ; Swaminathan, C. P. ; Surolia, Avadhesha ; Varadarajan, Raghavan (1997) Thermodynamic characterization of the reversible, two-state unfolding of maltose binding protein, a large two-domain protein Biochemistry, 36 (16). pp. 5020-5028. ISSN 0006-2960

Varadarajan, R. ; Nagarajaram, H. A. ; Ramakrishnan, C. (1996) A procedure for the prediction of temperature-sensitive mutants of a globular protein based solely on the amino acid sequence Proceedings of the National Academy of Sciences of the United States of America, 93 (24). pp. 13908-13913. ISSN 0027-8424

Nadig, Gautham ; Ratnaparkhi, Girish S. ; Varadarajan, Raghavan ; Vishveshwara, Saraswathi (1996) Dynamics of ribonuclease A and ribonuclease S: computational and experimental studies Protein Science, 5 (10). pp. 2104-2114. ISSN 0961-8368

Thomson, James ; Ratnaparkhi, Girish S. ; Varadarajan, Raghavan ; Sturtevant, Julian M. ; Richards, Frederic M. (1994) Thermodynamic and structural consequences of changing a sulfur atom to a methylene group in the M13Nle mutation in ribonuclease-S Biochemistry, 33 (28). pp. 8587-8593. ISSN 0006-2960

Thomson, James ; Ratnaparkhi, Girish S. ; Varadarajan, Raghavan ; Sturtevant, Julian M. ; Richards, Frederic M. (1994) Thermodynamic consequences of changing a sulfur atom to a methylene group in the M13Nle mutation in Ribonuclease-S Biochemistry, 33 (28). pp. 8587-8593. ISSN 0006-2960

Varadarajan, R. ; Richards, F. M. (1992) Crystallographic structures of ribonuclease S variants with nonpolar substitution at position 13: packing and cavities Biochemistry, 31 (49). pp. 12315-12327. ISSN 0006-2960

Kim, Eunice E. ; Varadarajan, Raghavan ; Wyckoff, Harold W. ; Richards, Frederic M. (1992) Refinement of the crystal structure of ribonuclease S. Comparison with and between the various ribonuclease A structures Biochemistry, 31 (49). pp. 12304-12314. ISSN 0006-2960

Varadarajan, Raghavan ; Connelly, Patrick R. ; Sturtevant, Julian M. ; Richards, Frederic M. (1992) Heat capacity changes for protein-peptide interactions in the ribonuclease S system Biochemistry, 31 (5). pp. 1421-1426. ISSN 0006-2960

Varadarajan, Raghavan ; Richards, Fredric M. ; Connelly, Patrick R. (1990) Proteins: the hard sphere, structure and energetics Current Science, 59 (17-18). pp. 819-824. ISSN 0011-3891

Connelly, Patrick R. ; Varadarajan, Raghavan ; Sturtevant, Julian M. ; Richards, Frederic M. (1990) Thermodynamics of protein-peptide interactions in the ribonuclease S system studied by titration calorimetry Biochemistry, 29 (25). pp. 6108-6114. ISSN 0006-2960

Varadarajan, Raghavan (1989) Electrostatic interactions in wild-type and mutant recombinant human myoglobins Biochemistry, 28 (9). pp. 3771-3781. ISSN 0006-2960

Varadarajan, R. ; Zewert, T. E. ; Gray, H. B. ; Boxer, S. G. (1989) Effects of buried ionizable amino acids on the reduction potential of recombinant myoglobin Science, 243 (4887). pp. 69-72. ISSN 0036-8075

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