Browse by Fellow

Sreekanth, Vedagopuram ; Kar, Animesh ; Kumar, Sandeep ; Pal, Sanjay ; Yadav, Poonam ; Sharma, Yamini ; Komalla, Varsha ; Sharma, Harsh ; Shyam, Radhey ; Sharma, Ravi Datta ; Mukhopadhyay, Arnab ; Sengupta, Sagar ; Dasgupta, Ujjaini ; Bajaj, Avinash (2021) Bile Acid Tethered Docetaxel‐Based Nanomicelles Mitigate Tumor Progression through Epigenetic Changes Angewandte Chemie International Edition, 60 (10). pp. 5394-5399. ISSN 1433-7851

Priya, Swati ; Kaur, Ekjot ; Kulshrestha, Swati ; Pandit, Awadhesh ; Gross, Isabelle ; Kumar, Nitin ; Agarwal, Himanshi ; Khan, Aamir ; Shyam, Radhey ; Bhagat, Prakash ; Prabhu, Jyothi S. ; Nagarajan, Perumal ; Deo, S. V. S. ; Bajaj, Avinash ; Freund, Jean-Noël ; Mukhopadhyay, Arnab ; Sengupta, Sagar (2021) CDX2 inducible microRNAs sustain colon cancer by targeting multiple DNA damage response pathway factors Journal of Cell Science, 134 (15). ISSN 0021-9533

Kaur, Ekjot ; Agrawal, Ritu ; Sengupta, Sagar (2021) Functions of BLM Helicase in Cells: Is It Acting Like a Double-Edged Sword? Frontiers in Genetics, 12 . ISSN 1664-8021

Tian, Rong ; Hussain, Mansoor ; Mohammed, Aftab ; Saifi, Shabnam ; Khan, Aamir ; Kaur, Ekjot ; Priya, Swati ; Agarwal, Himanshi ; Sengupta, Sagar (2021) MITOL-dependent ubiquitylation negatively regulates the entry of PolγA into mitochondria PLoS Biology, 19 (3). e3001139. ISSN 1545-7885

Sreekanth, Vedagopuram ; Pal, Sanjay ; Kumar, Sandeep ; Komalla, Varsha ; Yadav, Poonam ; Shyam, Radhey ; Sengupta, Sagar ; Bajaj, Avinash (2021) Self-assembled supramolecular nanomicelles from a bile acid–docetaxel conjugate are highly tolerable with improved therapeutic efficacy Biomaterials Science, 9 (16). pp. 5626-5639. ISSN 2047-4830

Rajarajan, Savitha ; C.Ε, Anupama ; Jose, Betsy ; Correa, Marjorie ; Sengupta, Sagar ; Prabhu, Jyothi (2020) Identification of colorectal cancers with defective DNA damage repair by immunohistochemical profiling of mismatch repair proteins, CDX2 and BRCA1 Molecular and Clinical Oncology, 13 (5). p. 1. ISSN 2049-9450

Lochab, Savita ; Singh, Yogendra ; Sengupta, Sagar ; Nandicoori, Vinay Kumar (2020) Mycobacterium tuberculosis exploits host ATM kinase for survival advantage through SecA2 secretome elife, 9 . ISSN 2050-084X

Tripathi, Vivek ; Kaur, Ekjot ; Kharat, Suhas Sampat ; Hussain, Mansoor ; Damodaran, Arun Prasath ; Kulshrestha, Swati ; Sengupta, Sagar (2019) Abrogation of FBW7α-dependent p53 degradation enhances p53’s function as a tumor suppressor Journal of Biological Chemistry, 294 (36). pp. 13224-13232. ISSN 0021-9258

Pal, Sanjay ; Medatwal, Nihal ; Kumar, Sandeep ; Kar, Animesh ; Komalla, Varsha ; Yavvari, Prabhu Srinivas ; Mishra, Deepakkumar ; Rizvi, Zaigham Abbas ; Nandan, Shiv ; Malakar, Dipankar ; Pillai, Manoj ; Awasthi, Amit ; Das, Prasenjit ; Sharma, Ravi Datta ; Srivastava, Aasheesh ; Sengupta, Sagar ; Dasgupta, Ujjaini ; Bajaj, Avinash (2019) A Localized Chimeric Hydrogel Therapy Combats Tumor Progression through Alteration of Sphingolipid Metabolism ACS Central Science, 5 (10). pp. 1648-1662. ISSN 2374-7943

Priyadarshini, Raina ; Hussain, Mansoor ; Attri, Preeti ; Kaur, Ekjot ; Tripathi, Vivek ; Priya, Swati ; Dhapola, Parashar ; Saha, Dhurjhoti ; Madhavan, Vinoth ; Chowdhury, Shantanu ; Sengupta, Sagar (2018) BLM Potentiates c-Jun Degradation and Alters Its Function as an Oncogenic Transcription Factor Cell Reports, 24 (4). 947-961.e7. ISSN 2211-1247

Tripathi, Vivek ; Agarwal, Himanshi ; Priya, Swati ; Batra, Harish ; Modi, Priyanka ; Pandey, Monica ; Saha, Dhurjhoti ; Raghavan, Sathees C. ; Sengupta, Sagar (2018) MRN complex-dependent recruitment of ubiquitylated BLM helicase to DSBs negatively regulates DNA repair pathways Nature Communications, 9 (1). ISSN 2041-1723

Sreekanth, Vedagopuram ; Medatwal, Nihal ; Pal, Sanjay ; Kumar, Sandeep ; Sengupta, Sagar ; Bajaj, Avinash (2017) Molecular Self-Assembly of Bile Acid-Phospholipids Controls the Delivery of Doxorubicin and Mice Survivability Molecular Pharmaceutics, 14 (8). pp. 2649-2659. ISSN 1543-8384

Sreekanth, Vedagopuram ; Medatwal, Nihal ; Kumar, Sandeep ; Pal, Sanjay ; Vamshikrishna, Malyla ; Kar, Animesh ; Bhargava, Priyanshu ; Naaz, Aaliya ; Kumar, Nitin ; Sengupta, Sagar ; Bajaj, Avinash (2017) Tethering of Chemotherapeutic Drug/Imaging Agent to Bile Acid-Phospholipid Increases the Efficacy and Bioavailability with Reduced Hepatotoxicity Bioconjugate Chemistry, 28 (12). pp. 2942-2953. ISSN 1043-1802

Kharat, S. S. ; Tripathi, V. ; Damodaran, A. P. ; Priyadarshini, R. ; Chandra, S. ; Tikoo, S. ; Nandhakumar, R. ; Srivastava, V. ; Priya, S. ; Hussain, M. ; Kaur, S. ; Fishman, J. B. ; Sengupta, S. (2016) Mitotic phosphorylation of Bloom helicase at Thr182 is required for its proteasomal degradation and maintenance of chromosomal stability Oncogene, 35 (8). pp. 1025-1038. ISSN 0950-9232

Kumari, Jyoti ; Hussain, Mansoor ; De, Siddharth ; Chandra, Suruchika ; Modi, Priyanka ; Tikoo, Shweta ; Singh, Archana ; Sagar, Chandrasekhar ; Sepuri, Naresh Babu V. ; Sengupta, Sagar (2016) Mitochondrial functions of RECQL4 are required for the prevention of aerobic glycolysis dependent cell invasion Journal of Cell Science . ISSN 0021-9533

Gupta, Shruti ; De, Siddharth ; Srivastava, Vivek ; Hussain, Mansoor ; Kumari, Jyoti ; Muniyappa, K. ; Sengupta, Sagar (2014) RECQL4 and p53 potentiate the activity of polymerase γ and maintain the integrity of the human mitochondrial genome Carcinogenesis, 35 (1). pp. 34-45. ISSN 0143-3334

Singh, Manish ; Kundu, Somanath ; Amarendar Reddy, M. ; Sreekanth, Vedagopuram ; Motiani, Rajender K. ; Sengupta, Sagar ; Srivastava, Aasheesh ; Bajaj, Avinash (2014) Injectable small molecule hydrogel as a potential nanocarrier for localized and sustained in vivo delivery of doxorubicin Nanoscale, 6 (21). pp. 12849-12855. ISSN 2040-3364

Rajanala, Kalpana ; Sarkar, Anshuk ; Jhingan, Gangan Deep ; Priyadarshini, Raina ; Jalan, Manisha ; Sengupta, Sagar ; Nandicoori, Vinay Kumar (2014) Phosphorylation of nucleoporin Tpr governs its differential localization and is required for its mitotic function Journal of Cell Science, 127 . pp. 3505-3520. ISSN 0021-9533

Tikoo, Shweta ; Madhavan, Vinoth ; Hussain, Mansoor ; Miller, Edward S. ; Arora, Prateek ; Zlatanou, Anastasia ; Modi, Priyanka ; Townsend, Kelly ; Stewart, Grant S. ; Sengupta, Sagar (2013) Ubiquitin-dependent recruitment of the Bloom Syndrome helicase upon replication stress is required to suppress homologous recombination EMBO Journal, 32 (12). pp. 1778-1792. ISSN 0261-4189

Jadav, Rathan S. ; Chanduri, Manasa V. L. ; Sengupta, Sagar ; Bhandari, Rashna (2013) Inositol pyrophosphate synthesis by inositol hexakisphosphate kinase 1 is required for homologous recombination repair Journal of Biological Chemistry, 288 (5). pp. 3312-3321. ISSN 0021-9258

Sreekanth, Vedagopuram ; Bansal, Sandhya ; Motiani, Rajender K. ; Kundu, Somanath ; Muppu, Sravan Kumar ; Majumdar, Tapodhara Datta ; Panjamurthy, Kuppusamy ; Sengupta, Sagar ; Bajaj, Avinash (2013) Design, synthesis, and mechanistic investigations of bile acid–tamoxifen conjugates for breast cancer therapy Bioconjugate Chemistry, 24 (9). pp. 1468-1484. ISSN 1043-1802

Chandra, Suruchika ; Priyadarshini, Raina ; Madhavan, Vinoth ; Tikoo, Shweta ; Hussain, Mansoor ; Mudgal, Richa ; Modi, Priyanka ; Srivastava, Vivek ; Sengupta, Sagar (2013) Enhancement of c-Myc degradation by BLM helicase leads to delayed tumor initiation Journal of Cell Science, 126 (16). pp. 3782-3795. ISSN 0021-9533

De, Siddharth ; Kumari, Jyoti ; Mudgal, Richa ; Modi, Priyanka ; Gupta, Shruti ; Futami, Kazunobu ; Goto, Hideyuki ; Lindor, Noralane M. ; Furuichi, Yasuhiro ; Mohanty, Debasisa ; Sengupta, Sagar (2012) RECQL4 is essential for the transport of p53 to mitochondria in normal human cells in the absence of exogenous stress Journal of Cell Science, 125 (10). pp. 2509-2522. ISSN 0021-9533

Kaur, Sarabpreet ; Modi, Priyanka ; Srivastava, Vivek ; Mudgal, Richa ; Tikoo, Shweta ; Arora, Prateek ; Mohanty, Debasisa ; Sengupta, Sagar (2010) Chk1-dependent constitutive phosphorylation of BLM helicase at serine 646 decreases after DNA damage Molecular Cancer Research, 8 (9). pp. 1234-1247. ISSN 1541-7786

Mehta, Surbhi ; Miklos, Ida ; Sipiczki, Matthias ; Sengupta, Sagar ; Sharma, Nimisha (2009) The Med8 mediator subunit interacts with the Rpb4 subunit of RNA polymerase II and Ace2 transcriptional activator inSchizosaccharomyces pombe FEBS Letters, 583 (19). pp. 3115-3120. ISSN 0014-5793

Srivastava, Vivek ; Modi, Priyanka ; Tripathi, Vivek ; Mudgal, Richa ; De, Siddharth ; Sengupta, Sagar (2009) BLM helicase stimulates the ATPase and chromatin-remodeling activities of RAD54 Journal of Cell Science, 122 (17). pp. 3093-3103. ISSN 0021-9533

Tripathi, Vivek ; Kaur, Sarabpreet ; Sengupta, Sagar (2008) Phosphorylation-dependent interactions of BLM and 53BP1 are required for their anti-recombinogenic roles during homologous recombination Carcinogenesis, 29 (1). pp. 52-61. ISSN 0143-3334

Pedeux, Remy ; Sengupta, Sagar ; Shen, Jiang Cheng ; Demidov, Oleg N. ; Saito, Shin'ichi ; Onogi, Hitoshi ; Kumamoto, Kensuke ; Wincovitch, Stephen ; Garfield, Susan H. ; McMenamin, Mary ; Nagashima, Makoto ; Grossman, Steven R. ; Appella, Ettore ; Harris, Curtis C. (2005) ING2 regulates the onset of replicative senescence by induction of p300-dependent p53 acetylation Molecular and Cellular Biology, 25 (15). pp. 6639-6648. ISSN 0270-7306

Sengupta, Sagar ; Harris, Curtis C. (2005) p53: traffic cop at the crossroads of DNA repair and recombination Nature Reviews Molecular Cell Biology, 6 . pp. 44-55. ISSN 1471-0072

Sengupta, Sagar ; Shimamoto, Akira ; Koshiji, Minori ; Pedeux, Remy ; Rusin, Marek ; Spillare, Elisa A. ; Shen, Jiang Cheng ; Eric Huang, L. ; Lindor, Noralane M. ; Furuichi, Yasuhiro ; Harris, Curtis C. (2005) Tumor suppressor p53 represses transcription of RECQ4 helicase Oncogene, 24 . pp. 1738-1748. ISSN 0950-9232

Sengupta, Sagar ; Robles, Ana I. ; Linke, Steven P. ; Sinogeeva, Natasha I. ; Zhang, Ran ; Pedeux, Remy ; Ward, Irene M. ; Celeste, Arkady ; Nussenzweig, André ; Chen, Junjie ; Halazonetis, Thanos D. ; Harris, Curtis C. (2004) Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest Journal of Cell Biology, 166 (6). pp. 801-813. ISSN 0021-9525

Sengupta, Sagar ; Wasylyk, Bohdan (2004) Physiological and pathological consequences of the interactions of the p53 tumor suppressor with the glucocorticoid, androgen, and estrogen receptors Annals of the New York Academy of Sciences, 1024 (1). pp. 54-71. ISSN 0077-8923

Perwez Hussain, S. ; Amstad, Paul ; He, Peijun ; Robles, Ana ; Lupold, Shawn ; Kaneko, Ichiro ; Ichimiya, Masato ; Sengupta, Sagar ; Mechanic, Leah ; Okamura, Shu ; Hofseth, Lorne J. ; Moake, Matthew ; Nagashima, Makoto ; Forrester, Kathleen S. ; Harris, Curtis C. (2004) p53-Induced Up-Regulation of MnSOD and GPx but not Catalase Increases Oxidative Stress and Apoptosis Cancer Research, 64 (7). pp. 2350-2356. ISSN 0008-5472

Yang, Qin ; Zhang, Ran ; Wang, Xin W. ; Linke, Steven P. ; Sengupta, Sagar ; Hickson, Ian D ; Pedrazzi, Graziella ; Perrera, Claudia ; Stagljar, Igor ; Littman, Susan J. ; Modrich, Paul ; Harris, Curtis C. (2004) The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase Oncogene, 23 . pp. 3749-3756. ISSN 0950-9232

Linke, Steven P. ; Sengupta, Sagar ; Khabie, Nissim ; Jeffries, Beth A. ; Buchhop, Sabine ; Miska, Stefan ; Henning, Wilhelm ; Pedeux, Remy ; Wang, Xin W. ; Hofseth, Lorne J. ; Yang, Qin ; Garfield, Susan H. ; Stürzbecher, Horst-Werner ; Harris, Curtis C. (2003) p53 interacts with hRAD51 and hRAD54, and directly modulates homologous recombination Cancer Research, 63 (10). pp. 2596-2605. ISSN 0008-5472

Sengupta, Sagar ; Linke, Steven P. ; Pedeux, Remy ; Yang, Qin ; Farnsworth, Julie ; Garfield, Susan H. ; Valerie, Kristoffer ; Shay, Jerry W. ; Ellis, Nathan A. ; Wasylyk, Bohdan ; Harris, Curtis C. (2003) BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination EMBO Journal, 22 (5). pp. 1210-1222. ISSN 0261-4189

Sengupta, Sagar ; Wasylyk, Bohdan (2001) Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2 Genes & Development, 15 (18). pp. 2367-2380. ISSN 0890-9369

Sengupta, Sagar ; Shaila, Melkote Subbarao ; Rao, Gannamani Ramananda (1997) A novel autophosphorylation mediated regulation of nitrite reductase inCandida utilis FEBS Letters, 416 (1). pp. 51-56. ISSN 0014-5793