Browse by Fellow

Number of items: 138.

Banerjee, Ushashi ; Rao, Pragati ; Reddy, Megha ; Hussain, Meeran ; Chunchanur, Sneha ; Ambica, R. ; Singh, Amit ; Chandra, Nagasuma (2022) A 9-gene biomarker panel identifies bacterial coinfections in culture-negative COVID-19 cases Molecular Omics, 18 (8). pp. 814-820. ISSN 2515-4184

Sankar, Santhosh ; Chandran Sakthivel, Naren ; Chandra, Nagasuma (2022) Fast Local Alignment of Protein Pockets (FLAPP): A System-Compiled Program for Large-Scale Binding Site Alignment Journal of Chemical Information and Modeling, 62 (19). pp. 4810-4819. ISSN 1549-9596

Chedere, Adithya ; Mishra, Madhulika ; Kulkarni, Omkar ; Sriraman, Shrisruti ; Chandra, Nagasuma (2022) Personalized quantitative models of NAD metabolism in hepatocellular carcinoma identify a subgroup with poor prognosis Frontiers in Oncology, 12 . ISSN 2234-943X

de Groot, Bert L. ; Sankar, Santhosh ; Chandra, Nagasuma (2022) SiteMotif: A graph-based algorithm for deriving structural motifs in Protein Ligand binding sites PLOS Computational Biology, 18 (2). e1009901. ISSN 1553-7358

Thakur, Chandrani ; Tripathi, Ashutosh ; Ravichandran, Sathyabaarathi ; Shivananjaiah, Akshatha ; Chakraborty, Anushree ; Varadappa, Sreekala ; Chikkavenkatappa, Nagaraj ; Nagarajan, Deepesh ; Lakshminarasimhaiah, Sharada ; Singh, Amit ; Chandra, Nagasuma (2022) A new blood-based RNA signature (R9), for monitoring effectiveness of tuberculosis treatment in a South Indian longitudinal cohort iScience, 25 (2). p. 103745. ISSN 25890042

Banerjee, Ushashi ; Baloni, Priyanka ; Singh, Amit ; Chandra, Nagasuma (2021) Immune Subtyping in Latent Tuberculosis Frontiers in Immunology, 12 . ISSN 1664-3224

Ravichandran, Sathyabaarathi ; Banerjee, Ushashi ; DR, Gayathri Devi ; Kandukuru, Rooparani ; Thakur, Chandrani ; Chakravortty, Dipshikha ; Balaji, Kithiganahalli Narayanaswamy ; Singh, Amit ; Chandra, Nagasuma (2021) VB10, a new blood biomarker for differential diagnosis and recovery monitoring of acute viral and bacterial infections EBioMedicine, 67 . p. 103352. ISSN 23523964

Banerjee, Ushashi ; Sankar, Santhosh ; Singh, Amit ; Chandra, Nagasuma (2020) A Multi-Pronged Computational Pipeline for Prioritizing Drug Target Strategies for Latent Tuberculosis Frontiers in Chemistry, 8 . ISSN 2296-2646

Sambaturu, Narmada ; Pusadkar, Vaidehi ; Hannenhalli, Sridhar ; Chandra, Nagasuma ; Valencia, Alfonso (2020) PathExt: a general framework for path-based mining of omics-integrated biological networks Bioinformatics . ISSN 1367-4803

Bhosle, Amrisha ; Datey, Akshay ; Chandrasekharan, Giridhar ; Singh, Deepshikha ; Chakravortty, Dipshikha ; Chandra, Nagasuma (2020) A Strategic Target Rescues Trimethoprim Sensitivity in Escherichia coli iScience, 23 (4). p. 100986. ISSN 2589-0042

Nagarajan, Deepesh ; Roy, Natasha ; Kulkarni, Omkar ; Nanajkar, Neha ; Datey, Akshay ; Ravichandran, Sathyabaarathi ; Thakur, Chandrani ; T., Sandeep ; Aprameya, Indumathi V. ; Sarma, Siddhartha P. ; Chakravortty, Dipshikha ; Chandra, Nagasuma (2019) Ω76: A designed antimicrobial peptide to combat carbapenem- and tigecycline-resistant Acinetobacter baumannii Science Advances, 5 (7). eaax1946. ISSN 2375-2548

Ravichandran, Sathyabaarathi ; Chandra, Nagasuma (2019) Interrogation of genome-wide networks in biology: comparison of knowledge-based and statistical methods International Journal of Advances in Engineering Sciences and Applied Mathematics, 11 (2). pp. 119-137. ISSN 0975-0770

Nagarajan, Deepesh ; Nagarajan, Tushar ; Nanajkar, Neha ; Chandra, Nagasuma (2019) A Uniform In Vitro Efficacy Dataset to Guide Antimicrobial Peptide Design Data, 4 (1). p. 27. ISSN 2306-5729

Bhagavat, Raghu ; Sankar, Santhosh ; Srinivasan, Narayanaswamy ; Chandra, Nagasuma (2018) An Augmented Pocketome: Detection and Analysis of Small-Molecule Binding Pockets in Proteins of Known 3D Structure Structure, 26 (3). 499-512.e2. ISSN 0969-2126

Gopalan, Akilandeswari ; Bhagavat, Raghu ; Chandra, Nagasuma ; Subbarao, Savithri Handanahal ; Raja, Alamelu ; Bethunaickan, Ramalingam (2018) Biophysical and biochemical characterization of Rv3405c, a tetracycline repressor protein from Mycobacterium tuberculosis Biochemical and Biophysical Research Communications, 496 (3). pp. 799-805. ISSN 0006-291X

Nagarajan, Deepesh ; Sukumaran, Sujeesh ; Deka, Geeta ; Krishnamurthy, Kiran ; Atreya, Hanudatta S. ; Chandra, Nagasuma (2018) Design of a heme-binding peptide motif adopting a β-hairpin conformation Journal of Biological Chemistry, 293 (24). pp. 9412-9422. ISSN 0021-9258

Mishra, Madhulika ; Jayal, Priyanka ; Karande, Anjali A. ; Chandra, Nagasuma (2018) Identification of a co‐target for enhancing efficacy of sorafenib in HCC through a quantitative modeling approach FEBS Journal, 285 (21). pp. 3977-3992. ISSN 1742-464X

Bhaskarla, Chetana ; Bhosale, Manoj ; Banerjee, Pip ; Chandra, Nagasuma ; Nandi, Dipankar (2018) Protein tagging, destruction and infection Current Protein & Peptide Science, 19 (2). 155- 171. ISSN 1389-2037

Viboud, Cecile ; Sambaturu, Narmada ; Mukherjee, Sumanta ; López-García, Martín ; Molina-París, Carmen ; Menon, Gautam I. ; Chandra, Nagasuma (2018) Role of genetic heterogeneity in determining the epidemiological severity of H1N1 influenza PLOS Computational Biology, 14 (3). e1006069. ISSN 1553-7358

Nagarajan, Deepesh ; Nagarajan, Tushar ; Roy, Natasha ; Kulkarni, Omkar ; Ravichandran, Sathyabaarathi ; Mishra, Madhulika ; Chakravortty, Dipshikha ; Chandra, Nagasuma (2017) Computational antimicrobial peptide design and evaluation against multidrug-resistant clinical isolates of bacteria Journal of Biological Chemistry . No pp. given. ISSN 0021-9258

Bhagavat, Raghu ; Srinivasan, Narayanaswamy ; Chandra, Nagasuma (2017) Deciphering common recognition principles of nucleoside mono/di and tri-phosphates binding in diverse proteins via structural matching of their binding sites Proteins: Structure, Function, and Bioinformatics, 85 (9). pp. 1699-1712. ISSN 0887-3585

Sahu, Umakant ; Rajendra, Vinod K. H. ; Kapnoor, Shankar S. ; Bhagavat, Raghu ; Chandra, Nagasuma ; Rangarajan, Pundi N. (2017) Methionine synthase is localized to the nucleus in Pichia pastoris and Candida albicans and to the cytoplasm in Saccharomyces cerevisiae Journal of Biological Chemistry, 292 . pp. 14730-14746. ISSN 0021-9258

Mudgal, Richa ; Srinivasan, Narayanaswamy ; Chandra, Nagasuma (2017) Resolving protein structure-function-binding site relationships from a binding site similarity network perspective Proteins: Structure, Function, and Bioinformatics, 85 (7). pp. 1319-1335. ISSN 0887-3585

Mishra, Saurabh ; Shukla, Prashant ; Bhaskar, Ashima ; Anand, Kushi ; Baloni, Priyanka ; Jha, Rajiv Kumar ; Mohan, Abhilash ; Rajmani, Raju S. ; Nagaraja, Valakunja ; Chandra, Nagasuma ; Singh, Amit (2017) Efficacy of β-lactam/β-lactamase inhibitor combination is linked to WhiB4-mediated changes in redox physiology of Mycobacterium tuberculosis elife, 6 . Article ID e25624. ISSN 2050-084X

Metri, Rahul ; Mohan, Abhilash ; Nsengimana, Jérémie ; Pozniak, Joanna ; Molina-Paris, Carmen ; Newton-Bishop, Julia ; Bishop, David ; Chandra, Nagasuma (2017) Identification of a gene signature for discriminating metastatic from primary melanoma using a molecular interaction network approach Scientific Reports, 7 . Article ID 17314. ISSN 2045-2322

Sambarey, Awanti ; Devaprasad, Abhinandan ; Baloni, Priyanka ; Mishra, Madhulika ; Mohan, Abhilash ; Tyagi, Priyanka ; Singh, Amit ; Akshata, J. S. ; Sultana, Razia ; Buggi, Shashidhar ; Chandra, Nagasuma (2017) Meta-analysis of host response networks identifies a common core in tuberculosis npj Systems Biology and Applications, 3 . Article ID 3. ISSN 2056-7189

Metri, Rahul ; Saxena, Shikhar ; Mishra, Madhulika ; Chandra, Nagasuma (2017) Modelling metabolic rewiring during melanoma progression using flux balance analysis In: IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 13-16 November 2017, Kansas City, MO, USA.

Sambarey, Awanti ; Devaprasad, Abhinandan ; Mohan, Abhilash ; Ahmed, Asma ; Nayak, Soumya ; Swaminathan, Soumya ; D'Souza, George ; Jesuraj, Anto ; Dhar, Chirag ; Babu, Subash ; Vyakarnam, Annapurna ; Chandra, Nagasuma (2017) Unbiased identification of blood-based biomarkers for pulmonary tuberculosis by modeling and mining molecular interaction networks EBioMedicine, 15 . pp. 112-126. ISSN 2352-3964

Korla, Kalyani ; Chandra, Nagasuma (2017) A systems perspective of signalling networks in host–pathogen interactions Journal of the Indian Institute of Science, 97 (1). pp. 41-57. ISSN 0970-4140

Mukherjee, Sumanta ; Bhattacharyya, Chiranjib ; Chandra, Nagasuma (2016) HLaffy: estimating peptide affinities for Class-1 HLA molecules by learning position-specific pair potentials Bioinformatics, 32 (15). pp. 2297-2305. ISSN 1367-4803

Ramakrishnan, Gayatri ; Jain, Abha ; Chandra, Nagasuma ; Srinivasan, Naraynaswamy (2016) Computational recognition and analysis of hitherto uncharacterized nucleotide cyclase-like proteins in bacteria Biology Direct, 11 . Article ID 27. ISSN 1745-6150

Marathe, Sandhya Amol ; Balakrishnan, Arjun ; Negi, Vidya Devi ; Sakorey, Deepika ; Chandra, Nagasuma ; Chakravortty, Dipshikha (2016) Curcumin reduces the motility of Salmonella enterica serovar Typhimurium by binding to the flagella, thereby leading to flagellar fragility and shedding Journal of Bacteriology, 13 . pp. 1798-1811. ISSN 0021-9193

Karyala, Prashanthi ; Metri, Rahul ; Bathula, Christopher ; Yelamanchi, Syam K. ; Sahoo, Lipika ; Arjunan, Selvam ; Sastri, Narayan P. ; Chandra, Nagasuma (2016) Denhunt - a comprehensive database of the intricate network of dengue-human interactions PLoS One Neglected Tropical Diseases, 10 (9). Article ID e0004965. ISSN 1932-6203

Dhar, Neha ; Mohan, Abhilash ; Thakur, Chandrani ; Chandra, Nagasuma R. ; Dighe, Rajan R. (2016) Dissecting the structural and functional features of the Luteinizing hormone receptor using receptor specific single chain fragment variables Molecular and Cellular Endocrinology, 427 . pp. 1-12. ISSN 0303-7207

Gilbert, Harry J ; Chandra, Nagasuma (2016) Editorial overview: Carbohydrate–protein interactions and glycosylation: integrating structural biology, informatics and systems modelling to understand glycan structure and glycan-protein interactions Current Opinion in Structural Biology, 40 . v-viii. ISSN 0959-440X

Chandrashekara, S. ; Anupamaa, K. R. ; Sambarey, Awanti ; Chandra, Nagasuma (2016) High IL-6 and low IL-15 levels mark the presence of TB infection: A preliminary study Cytokine, 81 . pp. 57-62. ISSN 1043-4666

Jose, Leny ; Ramachandran, Ranjit ; Bhagavat, Raghu ; Gomez, Roshna Lawrence ; Chandran, Aneesh ; Raghunandanan, Sajith ; Omkumar, Ramakrishnapillai Vyomakesannair ; Chandra, Nagasuma ; Mundayoor, Sathish ; Ajay Kumar, Ramakrishnan (2016) Hypothetical protein Rv3423.1 of Mycobacterium tuberculosis is a histone acetyltransferase FEBS Journal, 283 (2). pp. 265-281. ISSN 1742-464X

Padiadpu, Jyothi ; Baloni, Priyanka ; Anand, Kushi ; Munshi, Mohamed Husen ; Thakur, Chandrani ; Mohan, Abhilash ; Singh, Amit ; Chandra, Nagasuma (2016) Identifying and tackling emergent vulnerability in drug-resistant mycobacteria ACS Infectious Diseases, 2 (9). pp. 592-607. ISSN 2373-8227

Shivashankar, Nithin ; Patil, Sonali ; Bhosle, Amrisha ; Chandra, Nagasuma ; Natarajan, Vijay (2016) MS3ALIGN: an efficient molecular surface aligner using the topology of surface curvature BMC Bioinformatics, 17 . Article ID 26. ISSN 1471-2105

Padiadpu, Jyothi ; Mishra, Mahulika ; Sharma, Eshita ; Mala, Uchurappa ; Somasundaram, Kumar ; Chandra, Nagasuma (2016) Probing the druggability limits for enzymes of the nad biosynthetic network in glioma Journal of Chemical Information and Modeling, 56 (5). pp. 843-853. ISSN 1549-9596

Bhosle, Amrisha ; Chandra, Nagasuma (2016) Structural analysis of dihydrofolate reductases enables rationalization of antifolate binding affinities and suggests repurposing possibilities FEBS Journal, 283 (6). pp. 1139-1167. ISSN 1742-464X

Singh, Amandeep ; Bhagavat, Raghu ; Vijayana, M. ; Chandra, Nagasuma (2016) A comparative analysis of the DNA recombination repair pathway in mycobacterial genomes Tuberculosis, 99 . pp. 109-119. ISSN 1472-9792

Mudgal, Richa ; Sandhya, Sankaran ; Kumar, Gayatri ; Sowdhamini, Ramanathan ; Chandra, Nagsuma R. ; Srinivasan, Nrayanaswamy (2015) NrichD database: sequence databases enriched with computationally designed protein-like sequences aid in remote homology detection Nucleic Acids Research, 43 (D1). D300-D305. ISSN 0305-1048

Anand, Praveen ; Nagarajan, Deepesh ; Mukherjee, Sumanta ; Chandra, Nagasuma (2015) ABS–Scan: In silico alanine scanning mutagenesis for binding site residues in protein–ligand complex F1000Research, 3 . Article ID 214. ISSN 2046-1402

Baloni, Priyanka ; Chandra, Nagasuma (2015) Architectural plan of transcriptional regulation in Mycobacterium tuberculosis Trends in Microbiology, 23 (3). pp. 123-125. ISSN 0966-842X

Masood, Talha Bin ; Sandhya, Sankaran ; Chandra, Nagasuma ; Natarajan, Vijay (2015) CHEXVIS: a tool for molecular channel extraction and visualization BMC Bioinformatics, 16 . Article ID 119. ISSN 1471-2105

Mohan, Abhilash ; Padiadpu, Jyothi ; Baloni, Priyanka ; Chandra, Nagasuma (2015) Complete Genome Sequences of a Mycobacterium smegmatis Laboratory Strain (MC² 155) and Isoniazid-Resistant (4XR1/R2) Mutant Strains Genome Announcements, 3 (1). e01520-e01514. ISSN 2169-8287

Mohan, Abhilash ; Bhosle, Amrisha ; Chandra, Nagasuma (2015) Complete genome sequences of an Escherichia coli laboratory strain and trimethoprim-resistant (TMP32XR) mutant strains Genome Announcements, 3 (6). Article ID e01434-15. ISSN 2169-8287

Mudgal, Richa ; Sandhya, Sankaran ; Chandra, Nagasuma ; Srinivasan, Narayanaswamy (2015) De-DUFing the DUFs: deciphering distant evolutionary relationships of Domains of Unknown Function using sensitive homology detection methods Biology Direct, 10 . Article ID 38. ISSN 1745-6150

Mukherjee, Sumnta ; Warwicker, Jim ; Chandra, Nagasuma (2015) Deciphering complex patterns of class-I HLA–peptide cross-reactivity via hierarchical grouping Immunology and Cell Biology, 93 . pp. 522-532. ISSN 0818-9641

Nagarajan, Deepesh ; Deka, Geeta ; Rao, Megha (2015) Design of symmetric TIM barrel proteins from first principles BMC Biochemistry, 16 . Article ID 18. ISSN 1471-2091

Ramakrishnan, Gayatri ; Ochoa-Montaño, Bernardo ; Raghavender, Upadhyayula S. ; Mudgal, Richa ; Joshi, Adwait G. ; Chandra, Nagasuma R. ; Sowdhamini, Ramanathan ; Blundell, Tom L. ; Srinivasan, Narayanaswamy (2015) Enriching the annotation of Mycobacterium tuberculosis H37Rv proteome using remote homology detection approaches: insights into structure and function Tuberculosis, 95 (1). pp. 14-25. ISSN 1472-9792

Sambaturu, Narmada ; Mishra, Madhulika ; Chandra, Nagasuma (2015) EpiTracer - an algorithm for identifying epicenters in condition-specific biological networks In: 2015 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 9-12 November 2015, Washington, DC, USA.

Padiadpu, Jyothi ; Baloni, Priyanka ; Chandra, Nagasuma (2015) Gene expression profiles of wild-type and isoniazid-resistant strains of Mycobacterium smegmatis Data in Brief, 4 . pp. 186-189. ISSN 2352-3409

Ghosh, Soma ; Chandra, Nagasuma ; Vishveshwara, Saraswathi (2015) Mechanism of Iron-Dependent Repressor (IdeR) activation and DNA binding: a molecular dynamics and protein structure network study PLoS Computational Biology, 11 (12). Article ID e1004500. ISSN 1553-734X

Ramakrishnan, Gayatri ; Chandra, Nagasuma R. ; Srinivasan, Narayanaswamy (2015) Recognizing drug targets using evolutionary information: implications for repurposing FDA-approved drugs against Mycobacterium tuberculosis H37Rv Molecular BioSystems, 11 (12). pp. 3316-3331. ISSN 1742-206X

Metri, Rahul ; Hariharaputran, Sridhar ; Ramakrishnan, Gayatri ; Anand, Praveen ; Raghavender, Upadhyayula S. ; Ochoa-Montaño, Bernardo ; Higueruelo, Alicia P. ; Sowdhamini, Ramanathan ; Chandra, Nagasuma R. ; Blundell, Tom L. ; Srinivasan, Narayanaswamy (2015) SInCRe—structural interactome computational resource for Mycobacterium tuberculosis Database, 2015 (1). Article ID bav060. ISSN 1758-0463

Raghunath, Arathi ; Sambarey, Awanti ; Sharma, Neha ; Mahadevan, Usha ; Chandra, Nagasuma (2015) A molecular systems approach to modelling human skin pigmentation: identifying underlying pathways and critical components BMC Research Notes, 8 . Article ID 170. ISSN 1756-0500

Ghosh, S. ; Baloni, P. ; Vishveshwara, S. ; Chandra, N. (2014) Weighting schemes in metabolic graphs for identifying biochemical routes Systems and Synthetic Biology, 8 (1). pp. 47-57. ISSN 1872-5325

Bhagavat, Raghu ; Chandra, Nagasuma (2014) Common recognition principles across diverse sequence and structural families of sialic acid binding proteins Glycobiology, 24 (1). pp. 5-16. ISSN 0959-6658

Bhosle, Amrisha ; Chandra, Nagasuma (2014) Different cancer cell lines resistant to the same drug exhibit differences in folate pathway dynamics In: 2014 IEEE International Conference on Bioinformatics and Biomedicine, 2-5 November 2014, Belfast, UK.

Mudgal, Richa ; Sowdhamini, Ramanathan ; Chandra, Nagasuma ; Srinivasan, Narayanaswamy ; Sandhya, Sankaran (2014) Filling-in void and sparse regions in protein sequence space by protein-like artificial sequences enables remarkable enhancement in remote homology detection capability Journal of Molecular Biology, 426 (4). pp. 962-979. ISSN 0022-2836

Ramakrishnan, Gayatri ; Chandra, Nagasuma R. ; Srinivasan, Narayanaswamy (2014) From workstations to workbenches: Towards predicting physicochemically viable protein–protein interactions across a host and a pathogen IUBMB Life, 66 (11). pp. 759-774. ISSN 1521-6543

Mukherjee, Sumanta ; Chandra, Nagasuma (2014) Grouping of large populations into few CTL immune ‘response-types’ from influenza H1N1 genome analysis Clinical and Translational Immunology, 3 (8). Article ID e24. ISSN 2050-0068

Baloni, Priyanka ; Padiadpu, Jyothi ; Singh, Anupam ; Gupta, Kuldeepkumar R. ; Chandra, Nagasuma (2014) Identifying feasible metabolic routes in Mycobacterium smegmatis and possible alterations under diverse nutrient conditions BMC Microbiology, 14 . Article ID 276. ISSN 1471-2180

Pentakota, Satya Krishna ; Sandhya, Sankaran ; Sikarwar, Arun P. ; Chandra, Nagasuma ; Satyanarayana Rao, Manchanahalli R. (2014) Mapping post-translational modifications of mammalian testicular specific histone variant TH2B in tetraploid and haploid germ cells and their implications on the dynamics of nucleosome structure Journal of Proteome Research, 13 (12). pp. 5603-5617. ISSN 1535-3893

Anand, Praveen ; Nagarajan, Deepesh ; Mukherjee, Sumanta ; Chandra, Nagasuma (2014) PLIC: protein–ligand interaction clusters Database, 2014 . Article ID bau029. ISSN 1758-0463

Sambarey, Awanti ; Prashanthi, Karyala ; Chandra, Nagasuma (2013) Mining large-scale response networks reveals ‘topmost activities’ in Mycobacterium tuberculosis infection Scientific Reports, 3 . Article ID 2302. ISSN 2045-2322

Chandra, Nagasuma ; Padiadpu, Jyothi (2013) Network approaches to drug discovery Expert Opinion on Drug Discovery, 8 (1). pp. 7-20. ISSN 1746-0441

Nagarajan, Deepesh ; Chandra, Nagasuma (2013) PocketMatch (version 2.0): a parallel algorithm for the detection of structural similarities between protein ligand binding-sites In: 2013 National Conference on Parallel Computing Technologies (PARCOMPTECH), 21-23 February 2013, Bangalore, India.

Padiadpu, Jyothi ; Mukherjee, Sumanta ; Chandra, Nagasuma (2013) Rationalization and prediction of drug resistant mutations in targets for clinical anti-tubercular drugs Journal of Biomolecular Structure and Dynamics, 31 (1). pp. 44-58. ISSN 0739-1102

Ghosh, Soma ; Baloni, Priyanka ; Mukherjee, Sumanta ; Anand, Praveen ; Chandra, Nagasuma (2013) A multi-level multi-scale approach to study essential genes in Mycobacterium tuberculosis BMC Systems Biology, 7 . Article ID 132. ISSN 1752-0509

Vashisht, Rohit ; Mondal, Anupam Kumar ; Jain, Akanksha ; Shah, Anup ; Vishnoi, Priti ; Priyadarshini, . ; Bhattacharyya, Kausik ; Rohira, Harsha ; Bhat, Ashwini G. ; Passi, Anurag ; Mukherjee, Keya ; Choudhary, Kumari Sonal ; Kumar, Vikas ; Arora, Anshula ; Munusamy, Prabhakaran ; Subramanian, Ahalyaa ; Venkatachalam, Aparna ; Gayathri, S. ; Raja, Sweety ; Chitra, Vijaya ; Verma, Kaveri ; Zaheer, Salman ; Balaganesh, J. ; Gurusamy, Malarvizhi ; Razeeth, Mohammed ; Raja, Ilamathi ; Thandapani, Madhumohan ; Mevada, Vishal ; Soni, Raviraj ; Rana, Shruti ; Ramanna, Girish Muthagadhalli ; Raghavan, Swetha ; Subramanya, Sunil N. ; Kholia, Trupti ; Patel, Rajesh ; Bhavnani, Varsha ; Chiranjeevi, Lakavath ; Sengupta, Soumi ; Singh, Pankaj Kumar ; Atray, Naresh ; Gandhi, Swati ; Avasthi, Tiruvayipati Suma ; Nisthar, Shefin ; Anurag, Meenakshi ; Sharma, Pratibha ; Hasiya, Yasha ; Dash, Debas ; Sharma, Arun ; Scaria, Vinod ; Thomas, Zakir ; Chandra, Nagasuma ; Brahmachari, Samir K. ; Bhardwaj, Anshu (2012) Crowd sourcing a new paradigm for interactome driven drug target identification in Mycobacterium tuberculosis PLoS One, 7 (7). Article ID: e39808. ISSN 1932-6203

Anand, Praveen ; Yeturu, Kalidas ; Chandra, Nagasuma (2012) PocketAnnotate: towards site-based function annotation Nucleic Acids Research, 40 (W1). W400-W408. ISSN 0305-1048

Mishra, Saurabh ; Bhagavat, Raghu ; Chandra, Nagasuma ; Vijayarangan, Namperumalsamy ; Rajeswari, Haryadi ; Ajitkumar, Parthasarathi (2012) Cloning, expression, purification, and biochemical characterisation of the FIC motif containing protein of Mycobacterium tuberculosis Protein Expression and Purification, 86 (1). pp. 58-67. ISSN 1046-5928

Ananthasubramanian, Seshan ; Metri, Rahul ; Khetan, Ankur ; Gupta, Aman ; Handen, Adam ; Chandra, Nagasuma ; Ganapathiraju, Madhavi (2012) Mycobacterium tuberculosis and Clostridium difficille interactomes: demonstration of rapid development of computational system for bacterial interactome prediction Microbial Informatics and Experimentation, 2 . Article ID 4. ISSN 2042-5783

Yeturu, Kalidas ; Chandra, Nagasuma (2011) PocketAlign a novel algorithm for aligning binding sites in protein structures Journal of Chemical Information and Modeling, 51 (7). pp. 1725-1736. ISSN 1549-9596

Ghosh, Soma ; Prasad, K. V. S. ; Vishveshwara, Saraswathi ; Chandra, Nagasuma (2011) Rule-based modelling of iron homeostasis in tuberculosis Molecular BioSystems, 7 (10). pp. 2750-2768. ISSN 1742-206X

Chandra, Nagasuma ; Kumar, Dhiraj ; Rao, Kanury (2011) Systems biology of tuberculosis Tuberculosis, 91 (5). pp. 487-496. ISSN 1472-9792

Bhat, Ashwini G. ; Vashisht, Rohit ; Chandra, Nagasuma (2010) Modeling metabolic adjustment in Mycobacterium tuberculosis upon treatment with isoniazid Systems and Synthetic Biology, 4 (4). pp. 299-309. ISSN 1872-5325

Gupta, Prabuddha ; Rajeswari, Haryadi ; Arumugam, Muthu ; Mishra, Saurabh ; Bhagavat, Raghu ; Anand, Praveen ; Chandra, Nagasuma ; Srinivasan, Ramanujam ; Indi, Shantinath ; Ajitkumar, Parthasarathi (2010) Mycobacterium tuberculosis FtsZ requires at least one arginine residue at the C-terminal end for polymerization in vitro Acta Biochimica et Biophysica Sinica, 42 (1). pp. 58-69. ISSN 1672-9145

Padiadpu, Jyothi ; Vashisht, Rohit ; Chandra, Nagasuma (2010) Protein–protein interaction networks suggest different targets have different propensities for triggering drug resistance Systems and Synthetic Biology, 4 (4). pp. 311-322. ISSN 1872-5325

Chandra, Nagasuma ; Anand, Praveen ; Yeturu, Kalidas (2010) Structural bioinformatics: deriving biological insights from protein structures Interdisciplinary Sciences: Computational Life Sciences, 2 (4). pp. 347-366. ISSN 1913-2751

Yeturu, Kalidas ; Utriainen, Tapani ; Kemp, Graham J. L. ; Chandra, Nagasuma (2010) An automated framework for understanding structural variations in the binding grooves of MHC class II molecules BMC Bioinformatics, 11 (Supl 1). Article ID S55. ISSN 1471-2105

Raman, Karthik ; Bhat, Ashwini Gurudas ; Chandra, Nagasuma (2010) A systems perspective of host–pathogen interactions: predicting disease outcome in tuberculosis Molecular BioSystems, 6 (3). pp. 516-530. ISSN 1742-206X

Raman, Karthik ; Chandra, Nagasuma (2009) Flux balance analysis of biological systems: applications and challenges Briefings in Bioinformatics, 10 (4). pp. 435-449. ISSN 1467-5463

Das, Soma ; Suhas Venkataraman, Laxminarayana ; Chandra, Nagasuma ; Ravi, Vasanthapuram ; Desai, Anita (2009) Heat shock protein 70 on Neuro2a cells is a putative receptor for Japanese encephalitis virus Virology, 385 (1). pp. 47-57. ISSN 0042-6822

Chandra, Nagasuma (2009) Computational systems approach for drug target discovery Expert Opinion on Drug Discovery, 4 (12). pp. 1221-1236. ISSN 1746-0441

Raman, Karthik ; Vashisht, Rohit ; Chandra, Nagasuma (2009) Strategies for efficient disruption of metabolism in Mycobacterium tuberculosis from network analysis Molecular BioSystems, 5 . pp. 1740-1751. ISSN 1742-206X

Bhadra, Sahely ; Bhattacharyya, Chiranjib ; Chandra, Nagasuma R. ; Mian, Saira I. (2009) A linear programming approach for estimating the structure of a sparse linear genetic network from transcript profiling data Algorithms for Molecular Biology, 4 . Article ID 5. ISSN 1748-7188

Raman, Karthik ; Chandra, Nagasuma (2008) Mycobacterium tuberculosis interactome analysis unravels potential pathways to drug resistance BMC Microbiology, 8 . Article ID 234. ISSN 1471-2180

Kalidas, Yeturu ; Chandra, Nagasuma (2008) PocketDepth: A new depth based algorithm for identification of ligand binding sites in proteins Journal of Structural Biology, 161 (1). pp. 31-42. ISSN 1047-8477

Yeturu, Kalidas ; Chandra, Nagasuma (2008) PocketMatch: a new algorithm to compare binding sites in protein structures BMC Bioinformatics, 9 . Article ID 543. ISSN 1471-2105

Raman, Karthik ; Yeturu, Kalidas ; Chandra, Nagasuma (2008) targetTB: A target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis BMC Systems Biology, 2 . Article ID 109. ISSN 1752-0509

Bhattacharya, Sourangshu ; Bhattacharyya, Chiranjib ; Chandra, Nagasuma R. (2007) Comparison of protein structures by growing neighborhood alignments BMC Bioinformatics, 8 . Article ID 77. ISSN 1471-2105

Konkimalla, V. Badireenath ; Suhas, Venkatramana Laxminarayana ; Chandra, Nagasuma R. ; Gebhart, Erich ; Efferth, Thomas (2007) Diagnosis and therapy of oral squamous cell carcinoma Expert Review of Anticancer Therapy, 7 (3). pp. 317-329. ISSN 1473-7140

Kanade, Santosh R. ; Suhas, V. L. ; Chandra, Nagasuma ; Gowda, Lalitha R. (2007) Functional interaction of diphenols with polyphenol oxidase The Febs Journal, 274 (16). pp. 4177-4187. ISSN 0014-2956

Raman, Karthik ; Rajagopalan, Preethi ; Chandra, Nagasuma (2007) Hallmarks of mycolic acid biosynthesis: A comparative genomics study Proteins: Structure, Function, and Bioinformatics, 69 (2). pp. 358-368. ISSN 0887-3585

Dash, Banaja Priyardarshini ; Mukherjee, Sumanto ; Suhas, V. L. ; Chandra, Nagasuma (2007) Interaction profiling of T-cell epitopes with MHC-class I molecules Protein and Peptide Letters, 14 (6). 557- 564. ISSN 0929-8665

Verkhedkar, Ketki D. ; Raman, Karthik ; Chandra, Nagasuma R. ; Vishveshwara, Saraswathi (2007) Metabolome based reaction graphs of M. Tuberculosis and M. Leprae: a comparative network analysis PLoS One, 2 (9). Article ID e881. ISSN 1932-6203

Singh, Desh Deepak ; Chandran, Divya ; Jeyakani, Justin ; Chandra, Nagasuma (2007) Scanning the genome of Mycobacterium tuberculosis to identify potential lectins Protein and Peptide Letters, 14 (7). pp. 683-691. ISSN 0929-8665

Sriharsha, Shimoga Nagaraj ; Ranganath Pai, Karkala Sreedhara ; Suhas, . ; Shashikanth, Sheena ; Chandra, Nagasuma ; Prabhu, Kandigere Ramaiah (2007) Synthesis, docking and anti-tumor activity of β-L-1,3-Thiazolidine pyrimidine nucleoside analogues Medicinal Chemistry, 3 (5). pp. 425-432. ISSN 1573-4064

Chandra, Nagasuma R. ; Kumar, Nirmal ; Jeyakani, Justin ; Singh, Desh Deepak ; Gowda, Sharan B. ; Prathima, M. N. (2006) Lectindb: a plant lectin database Glycobiology, 16 (10). pp. 938-946. ISSN 0959-6658

Vinod, P. K. ; Konkimalla, Badireenath ; Chandra, Nagasuma (2006) In-silico pharmacodynamics: correlation of adverse effects of H2-antihistamines with histamine N-methyl transferase binding potential Applied Bioinformatics, 5 (3). pp. 141-150. ISSN 1175-5636

Chandra, Nagasuma (2006) Common scaffolds, diverse recognition profiles Structure, 14 (7). pp. 1093-1094. ISSN 0969-2126

Krishna, R. ; Manjunath, G. P. ; Kumar, P. ; Surolia, A. ; R. Chandra, Nagasuma ; Muniyappa, K. ; Vijayan, M. (2006) Crystallographic identification of an ordered C-terminal domain and a second nucleotide-binding site in RecA: new insights into allostery Nucleic Acids Research, 34 (8). pp. 2186-2195. ISSN 0305-1048

Ramesh, Sneha ; Bharath, M.M. Srinivas ; Chandra, Nagasuma R. ; Rao, Manchanahalli R. Satyanarayana (2006) A K52Q substitution in the globular domain of histone H1t modulates its nucleosome binding properties FEBS Letters, 580 (25). pp. 5999-6006. ISSN 0014-5793

Bhattacharya, Sourangshu ; Bhattacharyya, Chiranjib ; Chandra, Nagasuma R. (2006) Projections for fast protein structure retrieval BMC Bioinformatics, 7 (Supl 5). Article ID S5. ISSN 1471-2105

Prabu, J. Rajan ; Thamotharan, S. ; Khanduja, Jasbeer Singh ; Alipio, Emily Zabala ; Kim, Chang-Yub ; Waldo, Geoffrey S. ; Terwilliger, Thomas C. ; Segelke, Brent ; Lekin, Tim ; Toppani, Dominique ; Hung, Li-Wei ; Yu, Minmin ; Bursey, Evan ; Muniyappa, K. ; Chandra, Nagasuma R. ; Vijayan, M. (2006) Structure ofMycobacterium tuberculosisRuvA, a protein involved in recombination Acta Crystallographica Section F, 62 (8). pp. 731-734. ISSN 1744-3091

Chaitra, M.G. ; Hariharaputran, Sridhar ; Chandra, Nagasuma R. ; Shaila, M.S. ; Nayak, R. (2005) Defining putative T cell epitopes from PE and PPE families of proteins of Mycobacterium tuberculosis with vaccine potential Vaccine, 23 (10). pp. 1265-1272. ISSN 0264-410X

Raman, Karthik ; Rajagopalan, Preethi ; Chandra, Nagasuma (2005) Flux balance analysis of mycolic acid pathway: targets for anti-tubercular drugs PLoS One, 1 (5). Article ID e46. ISSN 1932-6203

Raval, Sujana ; Gowda, Sharan B. ; Singh, Desh D. ; Chandra, Nagasuma R. (2004) A database analysis of Jacalin-like lectins: sequence–structure–function relationships Glycobiology, 14 (12). pp. 1247-1263. ISSN 0959-6658

Dhanasekaran, Shanmugham ; Chandra, Nagasuma R. ; Chandrasekhar Sagar, B.K. ; Rangarajan, Pundi N. ; Padmanaban, Govindarajan (2004) δ-Aminolevulinic Acid Dehydratase from Plasmodium falciparum Journal of Biological Chemistry, 279 (8). pp. 6934-6942. ISSN 0021-9258

Prasad, Tejasvini ; Subramanian, Tamilselvi ; Hariharaputran, Sridhar ; Chaitra, H. S. ; Chandra, Nagasuma (2004) Extracting hydrogen-bond signature patterns from protein structure data Applied Bioinformatics, 3 (2-3). pp. 125-135. ISSN 1175-5636

Kumar, Pradeep ; Appu Rao, A. G. ; Hariharaputran, Sridhar ; Chandra, Nagasuma ; Gowda, Lalitha R. (2004) Molecular mechanism of dimerization of bowman-birk inhibitors. Pivotal role of ASP⁷⁶ in the dimerzation The Journal of Biological Chemistry, 279 . pp. 30425-30432. ISSN 0021-9258

Prasad, Tejasvini ; Prathima, M. N. ; Chandra, Nagasuma (2003) Detection of hydrogen-bond signature patterns in protein families Bioinformatics, 19 (1). pp. 167-168. ISSN 1367-4803

Ramachandraiah, G. ; Chandra, N. R. ; Surolia, A. ; Vijayan, M. (2003) Computational analysis of multivalency in lectins: structures of garlic lectin-oligosaccharide complexes and their aggregates Glycobiology, 13 (11). pp. 765-775. ISSN 0959-6658

Shobini, J. ; Mishra, A. K. ; Chandra, Nagasuma (2003) Conformation of gramicidin-A in CTAB micellar media Journal of Photochemistry and Photobiology B: Biology, 70 (2). pp. 117-124. ISSN 1011-1344

Datta, S. ; Krishna, R. ; Ganesh, N. ; Chandra, Nagasuma R. ; Muniyappa, K. ; Vijayan, M. (2003) Crystal Structures of Mycobacterium smegmatis RecA and Its Nucleotide Complexes Journal of Bacteriology, 185 (14). pp. 4280-4284. ISSN 0021-9193

Konkimalla, V. Badireenath ; Chandra, Nagasuma (2003) Determinants of histamine recognition: implications for the design of antihistamines Biochemical and Biophysical Research Communications, 309 (2). pp. 425-431. ISSN 0006-291X

Bharath, M. M. S. ; Nagasuma, R. Chandra ; M. R. S., Rao (2003) Molecular modeling of the chromatosome particle Nucleic Acids Research, 31 (14). pp. 4264-4274. ISSN 1362-4962

Bharath, M. M. S. ; Chandra, Nagasuma R. ; Rao, M. R. S. (2003) Molecular modeling of the chromatosome particle Nucleic Acids Research, 31 (14). pp. 4264-4274. ISSN 1362-4962

Datta, S. ; Ganesh, N. ; Chandra, Nagasuma R. ; Muniyappa, K. ; Vijayan, M. (2003) Structural studies on MtRecA-nucleotide complexes: Insights into DNA and nucleotide binding and the structural signature of NTP recognition Proteins: Structure, Function, and Bioinformatics, 50 (3). pp. 474-485. ISSN 0887-3585

Bharath, M. M. Srinivas ; Ramesh, Sneha ; Chandra, Nagasuma R. ; Rao, M. R. S. (2002) Identification of a 34 Amino Acid Stretch within the C-Terminus of Histone H1 As the DNA-Condensing Domain by Site-Directed Mutagenesis† Biochemistry, 41 (24). pp. 7617-7627. ISSN 0006-2960

Bharath, M.M. Srinivas ; Chandra, Nagasuma R. ; Rao, M.R.S. (2002) Prediction of an HMG-box fold in the C-terminal domain of histone H1: Insights into its role in DNA condensation Proteins: Structure, Function, and Bioinformatics, 49 (1). pp. 71-81. ISSN 0887-3585

Ramachandraiah, Gosu ; Chandra, Nagasuma R. ; Surolia, A. ; Vijayan, M. (2002) Re-refinement using reprocessed data to improve the quality of the structure: a case study involving garlic lectin Acta Crystallographica Section D, 58 (3). pp. 414-420. ISSN 0907-4449

Ghosh, Soma ; Chandra, Nagasuma ; Vishveshwara, Saraswathi 13 Influence of iron on iron dependent repressor (IdeR) activation and DNA binding Journal of Biomolecular Structure and Dynamics, 33 (Suppl). No pp. given.. ISSN 0739-1102

Anand, Praveen ; Chandra, Nagasuma Characterizing the pocketome of Mycobacterium tuberculosis and application in rationalizing polypharmacological target selection Scientific Reports . Article ID 119. ISSN 2045-2322

Ramakrishnan, Gayatri ; Chandra, Nagasuma ; Srinivasan, Narayanaswamy Exploring anti-malarial potential of FDA approved drugs: an in silico approach Malaria Journal, 16 (1). Article ID 290. ISSN 1475-2875

Bhagavat, Raghu ; Kim, Heung-Bok ; Kim, Chang-Yub ; Terwilliger, Thomas C. ; Mehta, Dolly ; Srinivasan, Narayanaswamy ; Chandra, Nagasuma A genome-wide structure-based survey of nucleotide binding proteins in M. tuberculosis Scientific Reports, 7 . Article ID 12489. ISSN 2045-2322

This list was generated on Mon Dec 23 03:06:20 2024 UTC.