Items where Author is "Nambiar, Mridula"

Kumari, Rupa ; Nambiar, Mridula ; Shanbagh, Shaika ; Raghavan, Sathees C. (2015) Detection of G-quadruplex DNA using primer extension as a tool PLoS One, 10 (3). Article ID e0119722, 14 pages. ISSN 1932-6203

Nambiar, Mridula ; Srivastava, Mrinal ; Gopalakrishnan, Vidya ; Sankaran, Sritha K. ; Raghavan, Sathees C. (2013) G-quadruplex structures formed at the HOX11 breakpoint region contribute to its fragility during t (10; 14) translocation in T-cell leukemia Molecular and Cellular Biochemistry, 33 (21). pp. 4266-4281. ISSN 0300-8177

Kavitha, Chandagirikoppal V. ; Nambiar, Mridula ; Narayanaswamy, Pavan B. ; Thomas, Elizabeth ; Rathore, Ujjwal ; Ananda Kumar, Channapillekoppalu S. ; Choudhary, Bibha ; Rangappa, Kanchugarakoppal S. ; Raghavan, Sathees C. (2013) Propyl-2-(8-(3, 4-difluorobenzyl)-2′, 5′-dioxo-8-azaspiro [bicyclo [3.2. 1] octane-3, 4′-imidazolidine]-1′-yl) acetate induces apoptosis in human leukemia cells through mitochondrial pathway following cell cycle arrest PLoS One, 8 (7). Article ID e69103, 10 pages. ISSN 1932-6203

Nambiar, Mridula ; Raghavan, Sathees C. (2013) Chromosomal translocations among the healthy human population: implications in oncogenesis Cellular and Molecular Life Sciences, 70 (8). pp. 1381-1392. ISSN 1420-682X

Srivastava, Mrinal ; Nambiar, Mridula ; Sharma, Sheetal ; Karki, Subhas S. ; Goldsmith, G. ; Hegde, Mahesh ; Kumar, Sujeet ; Pandey, Monica ; Singh, Ram K. ; Ray, Pritha ; Natarajan, Renuka ; Kelkar, Madhura ; De, Abhijit ; Choudhary, Bibha ; Raghavan, Sathees C. (2012) An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression Cell, 151 (7). pp. 1474-1487. ISSN 0092-8674

Katapadi, Vijeth K. ; Nambiar, Mridula ; Raghavan, Sathees C. (2012) Potential G-quadruplex formation at breakpoint regions of chromosomal translocations in cancer may explain their fragility Genomics, 100 (2). pp. 72-80. ISSN 0888-7543

Nambiar, Mridula ; Raghavan, Sathees C. (2012) Mechanism of fragility at BCL2 gene minor breakpoint cluster region during t (14; 18) chromosomal translocation The Journal of Biological Chemistry, 287 . pp. 8688-8701. ISSN 0021-9258

Shahabuddin, M. S. ; Nambiar, Mridula ; Moorthy, Balaji T. ; Naik, Prakruthi L. ; Choudhary, Bibha ; Advirao, Gopal M. ; Raghavan, Sathees C. (2011) A novel structural derivative of natural alkaloid ellipticine, MDPSQ, induces necrosis in leukemic cells Investigational New Drugs, 29 (4). pp. 523-533. ISSN 0167-6997

Karki, Subhas S. ; Panjamurthy, Kuppusamy ; Kumar, Sujeet ; Nambiar, Mridula ; Ramareddy, Sureshbabu A. ; Chiruvella, Kishore K. ; Raghavan, Sathees C. (2011) Synthesis and biological evaluation of novel 2-aralkyl-5-substituted-6-(4′-fluorophenyl)-imidazo [2, 1-b][1, 3, 4] thiadiazole derivatives as potent anticancer agents European Journal of Medicinal Chemistry, 46 (6). pp. 2109-2116. ISSN 0223-5234

Nambiar, Mridula ; Goldsmith, G. ; Moorthy, Balaji T. ; Lieber, Michael R. ; Joshi, Mamata V. ; Choudhary, Bibha ; Hosur, Ramakrishna V. ; Raghavan, Sathees C. (2011) Formation of a G-quadruplex at the BCL2 major breakpoint region of the t(14;18) translocation in follicular lymphoma Nucleic Acids Research, 39 (3). pp. 936-948. ISSN 0305-1048

Nambiar, Mridula ; Raghavan, Sathees C. (2011) How does DNA break during chromosomal translocations? Nucleic Acids Research, 39 (14). pp. 5813-5825. ISSN 0305-1048

Shahabuddin, M. S. ; Nambiar, Mridula ; Advirao, Gopal M. ; Raghavan, Sathees C. (2011) Intercalative pyrimido[4',5':4,5]thieno(2,3-b)quinolines induce apoptosis in leukemic cells: a comparative study of methoxy and morpholino substitution Investigational New Drugs, 29 (5). pp. 873-882. ISSN 0167-6997

Kumar, Tadi Satish ; Kari, Vijayalakshmi ; Chaudhary, Bibha ; Nambiar, Mridula ; Akila, T. S. ; Raghavan, Sathees C. (2010) Anti-apoptotic protein BCL2 down-regulates DNA end joining in cancer cells The Journal of Biological Chemistry, 285 (42). pp. 32657-32670. ISSN 0021-9258

Shahabuddin, M. S. ; Nambiar, Mridula ; Choudhary, Bibha ; Advirao, Gopal M. ; Raghavan, Sathees C. (2010) A novel DNA intercalator, butylamino-pyrimido [4′, 5′: 4, 5] selenolo (2, 3-b) quinoline, induces cell cycle arrest and apoptosis in leukemic cells Investigational New Drugs, 28 (1). pp. 35-48. ISSN 0167-6997

Nambiar, Mridula ; Raghavan, Sathees C. (2010) Prevalence and analysis of t (14; 18) and t (11; 14) chromosomal translocations in healthy Indian population Annals of Hematology, 89 . p. 35. ISSN 0939-5555

Kavitha, C. V. ; Nambiar, Mridula ; Ananda Kumar, C. S. ; Choudhary, Bibha ; Muniyappa, K. ; Rangappa, Kanchugarakoppal S. ; Raghavan, Sathees C. (2009) Novel derivatives of spirohydantoin induce growth inhibition followed by apoptosis in leukemia cells Biochemical Pharmacology, 77 (3). pp. 348-363. ISSN 0006-2952

Chiruvella, Kishore K. ; Kari, Vijayalakshmi ; Choudhary, Bibha ; Nambiar, Mridula ; Ghanta, Rama Gopal ; Raghavan, Sathees C. (2008) Methyl angolensate, a natural tetranortriterpenoid induces intrinsic apoptotic pathway in leukemic cells FEBS Letters, 582 (29). pp. 4066-4076. ISSN 0014-5793

Nambiar, Mridula ; Kari, Vijayalakshmi ; Raghavan, Sathees C. (2008) Chromosomal translocations in cancer Biochimica et Biophysica Acta: Reviews on Cancer, 1786 (2). pp. 139-152. ISSN 0304-419X

Nambiar, Mridula ; Choudhary, Bibha ; Rao, Clementina R. ; Raghavan, Sathees C. (2008) Amplification of chromosomal translocation junctions from paraffin-embedded tissues of follicular lymphoma patients Biomedical Materials, 3 (3). Article ID 034103. ISSN 1748-6041