Wavelet analysis of DNA walks

Haimovich, Adrian D. ; Byrne, Bruce ; Ramaswamy, Ramakrishna ; Welsh, William J. (2006) Wavelet analysis of DNA walks Journal of Computational Biology, 13 (7). pp. 1289-1298. ISSN 1066-5277

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Official URL: http://online.liebertpub.com/doi/abs/10.1089/cmb.2...

Related URL: http://dx.doi.org/10.1089/cmb.2006.13.1289

Abstract

A wavelet transform of the DNA "walk" constructed from a genomic sequence offers a direct visualization of short and long-range patterns in nucleotide sequences. We study sequences that encode diverse biological functions, taken from a variety of genomes. Pattern irregularities in the transform are frequently associated with sequences of biological interest. Exonic regions, for example, visualize differently under wavelet analysis than introns, and ribosomal RNA regions display distinct universal signatures. DNA walk wavelet analysis can provide a sensitive and rapid assessment of the putative biological significance of genomic DNA.

Item Type:Article
Source:Copyright of this article belongs to Mary Ann Liebert.
ID Code:98851
Deposited On:22 May 2015 12:12
Last Modified:22 May 2015 12:12

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