Lohray, Braj B. ; Baskaran, S. ; Rao, Bonthu Srinivasa ; Mallesham, B. ; Bharath, K. S. N. ; Reddy, Yadi B. ; Venkateswarlu, S. ; Sadhukhan, Ashok K. ; Kumar, Sitaram M. ; Sarnaik, Hemant M. (1998) Novel quinolone derivatives as potent antibacterials Bioorganic & Medicinal Chemistry Letters, 8 (5). pp. 525-528. ISSN 0960-894X
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/S0960-894X(98)00063-8
Abstract
Several 7-(3R,4R-N,N′-dialkyl diaminopyrrolidinyl)-substituted quinolones were synthesized and evaluated for antibacterial activities. 5-Amino-7-(3R,4R-N,N′-dimethyldiamino-6,8-difluoro-1,4-dihydro-1-cyclopropyl-4-oxoquinoline-3-carboxylic acid was found to have potent antibacterial activity against gram + ve organïsms.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 98568 |
| Deposited On: | 24 Sep 2014 11:47 |
| Last Modified: | 24 Sep 2014 11:47 |
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