A highly regio- and chemoselective reductive cleavage of benzylidene acetals with EtAlCl2-Et3SiH

Baskaran, Sundarababu ; Balakumar, Vijayakrishnan ; Aravind, Appu (2004) A highly regio- and chemoselective reductive cleavage of benzylidene acetals with EtAlCl2-Et3SiH Synlett (4). pp. 647-650. ISSN 0936-5214

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Official URL: https://www.thieme-connect.com/products/ejournals/...

Related URL: http://dx.doi.org/10.1055/s-2004-817752

Abstract

A highly regio- and chemoselective reductive cleavage of benzylidene acetals derived from 1,2- and 1,3-diols was achieved under mild conditions using EtAlCl2-Et3SiH reagent system in good to excellent yields. Labile protecting groups such as N-Boc, N-Cbz and -OTBDMS are found to be stable under the reaction conditions.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers Inc.
Keywords:Regioselectivity; Chemoselectivity; Reductive Cleavage; Benzylidene Acetal; EtAlCl2; Et3SiH
ID Code:98554
Deposited On:19 Sep 2014 11:49
Last Modified:19 Sep 2014 11:49

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