Dikshit, Madhu ; Srivastava, Ranjana ; Srimal, Rikhab Chand ; Dhawan, Bhola Nath (1989) Modification of ischemia-induced biochemical changes in the myocardium by Rooh-Afza extracts Drug Development Research, 17 (3). pp. 245-252. ISSN 0272-4391
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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/ddr.430...
Related URL: http://dx.doi.org/10.1002/ddr.430170308
Abstract
In rats, myocardial ischemia was produced by isoprenaline (80 mg/kg i.p.) and in rabbits, by ligating the anterior descending branch of the coronary artery. Two extracts of Rooh-Afza, a Unani polypharmaceutical preparation, were administered 1 hr or 15 min before inducing ischemia. Both the extracts protected the rat myocardium from isoprenaline-induced changes. In rabbits, protection against ischemia was observed only at a higher dose. The extract containing essential oils and flavoring agents was found to be more effective. It also inhibited platelet aggregation induced by adenosine diphosphate (ADP) in vitro and ex vivo in monkeys.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons, Inc. |
| Keywords: | Lactate Dehydroganase; Succinate Dehydrogenase; β-glucuronidase |
| ID Code: | 9688 |
| Deposited On: | 02 Nov 2010 11:01 |
| Last Modified: | 09 Feb 2011 08:24 |
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