Effect of a fungal interferon inducer (6-MFA) on macrophage functions during dengue virus infection

Nagar, Rachna ; Chaturvedi, U. C. ; Mathur, A. (1986) Effect of a fungal interferon inducer (6-MFA) on macrophage functions during dengue virus infection Indian Journal of Medical Microbiology, 4 (3). pp. 191-197. ISSN 0255-0857

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Official URL: http://www.ijmm.org/article.asp?issn=0255-0857;yea...

Abstract

Effect of 6-MFA, an interferon inducer of fungal origin having antiviral activity, was investigated on the functions of macrophages during dengue virus (DV) infection. It was observed that treatment of mice with 6-MFA abrogated the DV induced depression of attachment and phagocytosis of opsonized sheep erythrocytes by the peritoneal macrophages. This effect appears to be mediated by interferon. 6-MFA had no effect on the outcome of infection.

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Deposited On:09 Jan 2013 06:39
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