Stereocontrolled approach to the highly functionalized bicyclo[3.2.0] heptane core of bielschowskysin through intramolecular Cu(I)-catalyzed [2+2] photocycloaddition

Jana, Anupam ; Mondal, Sujit ; Hossain, Firoj Md. ; Ghosh, Subrata (2012) Stereocontrolled approach to the highly functionalized bicyclo[3.2.0] heptane core of bielschowskysin through intramolecular Cu(I)-catalyzed [2+2] photocycloaddition Tetrahedron Letters, 53 (50). pp. 6830-6833. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2012.10.018

Abstract

A direct route for the synthesis of highly functionalized bicyclo[3.2.0]heptane core containing the bridged lactone with the functionalized C-12 substituent of bielschowskysin is reported. The key step involves a stereoselective Cu (I)-catalyzed [2+2] photocycloaddition of a 1,6-diene embedded in a sugar derivative.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:96427
Deposited On:19 Dec 2012 06:37
Last Modified:19 Dec 2012 06:37

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