Fibrinogen and homocysteine levels in coronary artery disease

Gheye, S. ; Krishna, T. P. ; Krishnaswamy, K. ; Lakshmi, A. V. (1999) Fibrinogen and homocysteine levels in coronary artery disease Indian Heart Journal, 51 (5). pp. 499-502. ISSN 0019-4832

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Conventional risk factors like high serum cholesterol, smoking and hypertension do not explain all the mortality and morbidity due to coronary artery disease in Indian population. Novel factors like plasma fibrinogen and homocysteine have been currently recognised as independent risk factors for coronary artery disease. A case-control study was carried out to examine the role of plasma fibrinogen, homocysteine, lipid profile and anthropometric parameters in angiographically established coronary artery disease patients. The relationship between the biochemical and anthropometric parameters was also examined. Fifty-eight male patients in the age range of 35-60 years with angiographically established coronary artery disease and equal number of matched-controls were the subjects of this study. Cases with coronary artery disease had significantly higher waist-to-hip ratio, waist-to-thigh ratio, plasma fibrinogen and total cholesterol. Mean plasma total homocysteine levels were not significantly different between cases and controls. In Indian population, elevated plasma fibrinogen and abdominal obesity appear to be significantly associated with coronary artery disease.

Item Type:Article
Source:Copyright of this article belongs to Cardiological Society of India.
ID Code:96368
Deposited On:14 Dec 2012 12:19
Last Modified:14 Dec 2012 12:19

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