Polyamines exert regulatory control on mycobacterial transcription: a study using RNA polymerase from Mycobacterium phlei

Sarkar, N. K. ; Shankar, S. ; Tyagi, A. K. (1995) Polyamines exert regulatory control on mycobacterial transcription: a study using RNA polymerase from Mycobacterium phlei Biochemistry & Molecular Biology International, 35 (6). pp. 1189-1198. ISSN 1039-9712

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Abstract

We have used purified RNA polymerase from Mycobacterium phlei to study the role of polyamines in mycobacterial transcription. Both initiation and elongation phases of the process were affected biphasically by polyamines. Interaction of polyamines with DNA template plays an important role in transcription modulation. Our studies emphasize that polyamines can exert a regulatory control on mycobacterial transcription.

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Deposited On:11 Jan 2013 10:38
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