Arunkumar, M. J. ; Ranjan, A. ; Jacob, M. ; Rajshekhar, V. (2001) Neurocutaneous melanosis: a case of primary intracranial melanoma with metastasis Clinical Oncology, 13 (1). pp. 52-54. ISSN 0936-6555
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1053/clon.2001.9215
Abstract
Neurocutaneous melanosis is a rare disorder characterized by the presence of large or multiple congenital melanocytic naevi and benign or malignant pigment cell tumours of the leptomeninges. Distant metastasis is unusual in primary leptomeningeal/intracranial melanomas. We present the case history of an adult male who had multiple primary intracranial melanomas associated with neurocutaneous melanosis (naevus of Ota) in the ophthalmic division of the left trigeminal nerve. Excision of the intracranial tumours was carried out in two stages, but the patient died 2 days after the second operation. Autopsy showed multiple metastatic deposits in the liver. Symptoms and signs of raised intracranial pressure, the presence of Ota's naevus, and a dural-based mass or masses should alert the treating physician to suspect a primary leptomeningeal/intracranial melanoma.
Item Type: | Article |
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Source: | Copyright of this article belongs to Elsevier Science. |
Keywords: | Metastasis; Multiple Intracranial Melanomas; Neurocutaneous Melanosis |
ID Code: | 95490 |
Deposited On: | 08 Aug 2013 11:56 |
Last Modified: | 08 Aug 2013 11:56 |
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