Aggarwal, R. ; Kochhar, R. ; Gupta, B. B. ; Goenka, M. K. ; Mehta, S. K. (1990) Controlled trial of twice a day versus once a day cimetidine therapy for duodenal ulcer Journal of the Association of Physicians of India, 38 (12). pp. 917-918. ISSN 0004-5772
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Abstract
A randomized controlled trial was carried out to compare the efficacy of conventional 400 mg twice daily dose of cimetidine with single bedtime 800 mg dose, in 40 patients with endoscopically proven duodenal ulcer. At repeat endoscopy after four weeks of therapy, complete ulcer healing was achieved in 78% of patients on twice daily dosage and 79% of patients on single daily dosage. A more convenient single nocturnal dosage of cimetidine is as effective in the treatment of duodenal ulcer as a twice daily dosage in the Indian population.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Association of Physicians of India. |
| ID Code: | 95488 |
| Deposited On: | 27 Sep 2013 04:59 |
| Last Modified: | 27 Sep 2013 04:59 |
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