Rao, Aruna V. ; Jain, Padam C. ; Anand, Nitya ; Srimal, R. C. ; Dua, Prithvi R. (1970) Agents acting on the central nervous system. XIII. 2,3,4,4a,5,6-hexahydro-1(H)-pyrazino[1,2-a]quinolines. A new class of hypotensive agents Journal of Medicinal Chemistry, 13 (3). pp. 516-522. ISSN 0022-2623
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Official URL: http://pubs.acs.org/doi/abs/10.1021/jm00297a039
Related URL: http://dx.doi.org/10.1021/jm00297a039
Abstract
The synthesis and pharmacological evaluation of a number of 3-substituted 2,3,4,4a,5,6-hexahydro-1(H)-pyrazino are reported. Them compounds in general show hypotensive and adrenergic-receptor blocking activity. The hypotensive activity is particularly marked in 3-β-phenethy and 3-y-(p-fiuorobenxoy1)propy1-2,3,4,4a,5,6-hexahydrod-1(H)pyrazino[1,2-a]quinolines.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society. |
| ID Code: | 95107 |
| Deposited On: | 15 Feb 2013 05:11 |
| Last Modified: | 15 Feb 2013 05:12 |
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