Studies in protoberberine alkaloids: Part I. New synthesis of tetrahydroberberine & epiberberine

Govindachari, T. R. ; Nagarajan, K. (1970) Studies in protoberberine alkaloids: Part I. New synthesis of tetrahydroberberine & epiberberine Indian Journal of Chemistry, 8 . pp. 763-765. ISSN 0019-5103

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Abstract

Alkali induced disproportionation of 7,8-dimethoxy-2-(3',4'-methylenedioxyphenethyl)iso-quinolinium bromide (XIII) and 2-(3',4'-dimethoxyphenethyl)-7,8-methylenedioxyisoquinolmium bromide (XVII) affords the corresponding dihydroisoquinolines which on cyclization with alcoholic hydrochloric acid give tetrahydroberberine (VIII) and tetrahydroepiberberine (IX) respectively.

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Deposited On:19 Jun 2012 07:19
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