Nagarajan, K. ; Arya, V. P. ; George, T. ; Bhat, G. A. ; Kulkarni, Y. S. ; Shenoy, S. J. ; Rao, M. K. (1982) Nitroimidazoles: Part VII. 1- (1-Alkyl-5-nitroimidazol-2-yl)-aza (diaza, oxaza) cycloakanes Indian Journal of Chemistry, 21B . pp. 949-952. ISSN 0019-5103
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Abstract
Reaction of 1-methyl-2-methylsulphonyI-5-nitroimidazole (2) with pyrrolidine, piperidine and morpholine affords the amines(3a-c)(=9a-c) respectively in low yields, the reaction failing with other bases tried. Analogues (9d-t) have been obtained more readily by nitrating imidazoles (8), which are sy'nthesised from thioureas (5) of cyclic secondary amines through the S-methylisothioureas (6) and the guanidinoaeetals (7).
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to National Institute of Science Communication and Information Resources. |
| ID Code: | 93425 |
| Deposited On: | 16 Jun 2012 09:29 |
| Last Modified: | 19 May 2016 06:30 |
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