Effect of 2-allyl-2-isopropylacetamide on poly(adenylic acid)-containing ribonucleic acid

Sardana, M. K. ; Padmanaban, G. (1982) Effect of 2-allyl-2-isopropylacetamide on poly(adenylic acid)-containing ribonucleic acid Biochemical Journal, 158 (2). pp. 169-174. ISSN 0264-6021

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Official URL: http://www.biochemj.org/bj/158/bj1580169.htm

Abstract

A single administration of 2-allyl-2-isopropylacetamide, a porphyrinogenic drug, enhanced the 32P-labelling of nucleoplasmic as well as cytoplasmic poly(A)-containing RNA in rat liver. The synthesis of total microsomal RNA is only marginally increased under these conditions. The drug enhances the labelling of a variety of cytoplasmic poly(A)-containing RNA species, and this effect is counteracted by the simultaneous administration of haemin. 2-Allyl-2-isopropylacetamide also enhanced the release of RNA from the nucleus to the cytoplasm.

Item Type:Article
Source:Copyright of this article belongs to Portland Press.
ID Code:91988
Deposited On:25 May 2012 13:56
Last Modified:25 May 2012 13:56

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