Vasudev, Prema G. ; Chatterjee, Sunanda ; Ananda, Kuppanna ; Shamala, Narayanaswamy ; Balaram, Padmanabhan (2008) Hybrid αβ polypeptides: structural characterization of a C12/C10 helix with alternating hydrogen-bond polarity Angewandte Chemie International Edition, 47 (34). pp. 6430-6432. ISSN 1433-7851
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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/anie.20...
Related URL: http://dx.doi.org/10.1002/anie.200801665
Abstract
A different twist: A mixed C12/C10 helix with alternating hydrogen-bond directionality has been observed in the crystal structure of the hybrid αβ peptide Boc-Leu-Gpn-Leu-Aib-OMe (see structure; Boc: tert-butoxycarbonyl; Leu: leucine; Gpn: 1-(aminomethyl)cyclohexaneacetic acid (gabapentin); Aib: aminoisobutyric acid). The structure may be generalized to a regular mixed helix.
Item Type: | Article |
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Source: | Copyright of this article belongs to John Wiley and Sons. |
Keywords: | Amino Acids; Helical Structures; Hydrogen Bonds; Peptides; Structure Elucidation |
ID Code: | 91483 |
Deposited On: | 21 May 2012 12:54 |
Last Modified: | 21 May 2012 12:54 |
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