Nagarajan, K. ; Talwalker, P. K. ; Shenoy, S. J. (1988) 1-Substituted-2,6,6-trimethyl-3-(1-oxo-3-hydroxy-5,5-dimethyl-2-cyclohexen-2-yl)-4-oxo-4,5,6,7-tetrahydroindoles: a novel class of potent hypoglycemic agents European Journal of Medicinal Chemistry, 23 (2). pp. 189-191. ISSN 0223-5234
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Official URL: http://www.sciencedirect.com/science/article/pii/0...
Related URL: http://dx.doi.org/10.1016/0223-5234(88)90193-6
Abstract
1-Phenyl-2,6,6-trimethyl-3-(1-oxo-3-hydroxy-5,5-dimethyl-2-cyclohexen-2-yl)-4-oxo-4,5,6,7-tetrahydroindole (II) (CGI 14600) is a novel substance with marked hypoglycemic activity in the rat. While structurally very different from sulphonylureas, II has a similar biological profile, including stimulation of insulin release.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | CGI 14600; Tetrahydroindole; Hypoglycemic |
| ID Code: | 90763 |
| Deposited On: | 14 May 2012 04:43 |
| Last Modified: | 14 May 2012 04:43 |
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