Anjaneyulu, B. ; Nagarajan, K. (1987) Synthesis of [Imidazolidinone-2-14C]Go 10213 (satranidazole, cibemid Journal of Labelled Compounds and Radiopharmaceuticals, 24 (4). pp. 423-430. ISSN 0362-4803
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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/jlcr.25...
Related URL: http://dx.doi.org/10.1002/jlcr.2580240409
Abstract
For additional pharmacokinetic and metabolism studies in laboratory animals and in humans, Go 10213 was labelled with carbon-14 located on the carbonyl carbon atom of the ethyleneurea ring (Ring B) of the molecule. [imidazolidinone-2-14C]Go 10213 having a specific activity of 6.06 µCi/mg (1.75 mCi/mmol) was synthesised starting with [14C]ethyleneurea in two steps.
Item Type: | Article |
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Source: | Copyright of this article belongs to John Wiley and Sons. |
Keywords: | Synthesis; Go 10213; Ethyleneurea; carbon-14 |
ID Code: | 90761 |
Deposited On: | 14 May 2012 04:43 |
Last Modified: | 14 May 2012 04:43 |
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