Rawat, S. ; Mathur, A. ; Chaturvedi, U. C. (1986) Characterization of Japanese encephalitis virus-induced suppressor T cells and their products for delayed type hypersensitivity British Journal of Experimental Pathology, 67 (4). pp. 571-579. ISSN 0007-1021
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Abstract
Intraperitoneal inoculation with Japanese encephalitis virus (JEV) induces the generation of T suppressor cells for delayed type hypersensitivity (Ts-DTH) in Swiss albino mice. The Ts-DTH are hydrocortisone resistant, partially sensitive to X-irradiation and the membrane phenotype of Ts cells is Ly I+. Ts-DTH suppression is mediated through the production of soluble suppressor factor (SF-DTH). SF-DTH is non-dialysable but passes through 450 nm filter and does not sediment after centrifugation at 100,000 g for 2 h; chromatography on Sephadex G-100 indicates an approximate molecular weight of 12,000.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Lewis, London. |
| ID Code: | 90650 |
| Deposited On: | 11 May 2012 07:41 |
| Last Modified: | 25 Jun 2012 10:30 |
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