Rawat, S. ; Mathur, A. ; Chaturvedi, U. C. (1986) Characterization of Japanese encephalitis virus-specific suppressor T cells and their product in suppression of the humoral immune response in mice Annales de l'Institut Pasteur Immunology, 137D (3). pp. 391-401. ISSN 0769-2625
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Official URL: http://www.sciencedirect.com/science/journal/07692...
Abstract
Since Japanese encephalitis virus (JEV) induces the generation of suppressor T cells in mouse spleen which, through the production of a soluble suppressor factor (SF), suppress IgM plaque-forming cells (IgM-PFC) the present study was undertaken to further characterize these suppressor cells and the SF. The suppressor cells were Ly1-2+ and sensitive to hydrocortisone and a high dose of irradiation. SF was trypsin-sensitive, thermolabile and non-dialysable, and passed through a 450-nm filter. This SF was shown to be a low molecular weight substance, with an approximate MW of 18,000 daltons.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 90648 |
| Deposited On: | 11 May 2012 07:04 |
| Last Modified: | 25 Jun 2012 10:30 |
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