Khare, P. D. ; Dhawan, R. ; Chaturvedi, U. C. (1996) Identification and characterization of receptor for dengue virus-induced macrophage cytotoxin Indian Journal of Experimental Biology, 34 (7). pp. 652-657. ISSN 0019-5189
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Abstract
The present study was undertaken to identify the receptor for dengue virus type 2 (DV) induced macrophage cytotoxin (CF2) on mouse peritoneal macrophages (MPhi). The binding of 125I-labelled CF2 to MPhi was saturable (15 nM), reversible, temperature, pH- and time-dependent. The saturation concentration was similar to that causing cell death. Scatchard analysis showed the presence of intermediate type of affinity receptor and the number of receptor sites was 1.1 × 10(6) per cell with dissociation constant of 14.28 nM.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to National Institute of Science Communication and Information Resources. |
| ID Code: | 90525 |
| Deposited On: | 10 May 2012 10:36 |
| Last Modified: | 10 May 2012 10:36 |
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