Role of nitric oxide in transmission of dengue virus specific suppressor signal

Khare, M. ; Chaturvedi, U. C. (1997) Role of nitric oxide in transmission of dengue virus specific suppressor signal Indian Journal of Experimental Biology, 35 (8). pp. 855-860. ISSN 0019-5189

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Abstract

Production of NO2- was maximum when peritoneal M phi was incubated with SF (40 mg) for 45 min. Pretreatment of M phi with anti-SF-antisera inhibited production of NO2- Pretreatment of M phi with NG monomethyl L-arginine (L-NMA) or arginase, an inhibitor of L-arginine dependent pathway, inhibited production of NO2- and transmission of suppressor signal in a dose-dependent manner. This indicates that NO and Ca2+ serve as intracellular signal in transmission of DV-induced suppressor signal.

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ID Code:90522
Deposited On:10 May 2012 10:36
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