Madhusudan, K. ; Ramesh, V. ; Nagaraja, V. (1994) Cloning and sequence analysis of DNA gyrase genes from Mycobacterium tuberculosis Current Science, 66 (9). pp. 664-667. ISSN 0011-3891
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Abstract
Using a heterologous DNA gyrase probe from Streptomyces sphaeroides, we have cloned the gyrA and gyrB genes of Mycobacterium tuberculosis. The M. tuberculosis gyrB gene has been sequenced and compared with the amino acid sequences of GyrB from other bacteria. There is a significant level (60-80%) of amino acid sequence homology between GyrB of M tuberculosis and that of other bacterial species, indicating a high degree of conservation of this essential enzyme.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Current Science Association. |
| ID Code: | 89550 |
| Deposited On: | 28 Apr 2012 14:28 |
| Last Modified: | 19 May 2016 04:04 |
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