Kumar, Pradeep ; Pandey, Menaka ; Gupta, Priti ; Dhavale, Dilip D. (2010) An organocatalytic route to the synthesis of lactone moiety of compactin and mevinolin Tetrahedron Letters, 51 (44). pp. 5838-5839. ISSN 0040-4039
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2010.08.093
Abstract
An efficient synthesis of lactone moiety of compactin has been achieved. The stereogenic centers were generated by means of iterative proline-catalyzed sequential α-aminoxylation and Horner-Wadsworth-Emmons (HWE) olefination of aldehydes.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Lactone; Proline; Organocatalysis; Aminoxylation; Compactin |
| ID Code: | 87229 |
| Deposited On: | 16 Mar 2012 06:14 |
| Last Modified: | 19 Mar 2012 11:32 |
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