Joshi, B. S. ; Pelletier, S. W. (1999) A cautionary note on the use of commercial (R)-MTPA-Cl and (S)-MTPA-Cl in determination of absolute configuration by Mosher ester analysis Heterocycles, 51 (1). pp. 183-184. ISSN 0385-5414
Full text not available from this repository.
Official URL: http://sciencelinks.jp/j-east/article/199909/00001...
Abstract
While the absolute configuration of a Mosher ester derivative (MTPAOR) is identical with that of the Mosher acid (MTPAOH) precursor, it is opposite that of the Mosher acid chloride (MTPA-Cl). Since (R)-MTPA-Cl and (S)-MTPA-Cl are now commercially available, incorrect conclusions may be drawn in deriving the absolute configuration, if this fact is overlooked. The absolute configuration of (−)-vasicinone (1) derived by Mosher ester analysis has been revised as 3S. Mosher ester analysis of (−)-vasicine (2) confirmed a 3S configuration for this alkloid.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Japan Institute of Heterocyclic Chemistry. |
| ID Code: | 86863 |
| Deposited On: | 13 Mar 2012 15:03 |
| Last Modified: | 13 Mar 2012 15:03 |
Repository Staff Only: item control page
