Cobalt catalysed carbonylation of organic halides under solid-liquid phase transfer conditions

Abstract

Organic halides are carbonylated under solid liquid phase transfer conditions using Co^-(CO)4 as catalyst under CO (1 atmosphere) at 25°C to afford corresponding esters in good yields. No Carbonylation is effected in absence of phase transfer agent (PTA). The striking example is the carbonylation of ethyl haloacetate to diethyl malonate, an important organic intermediate. The parameters such as concentration of PTA, and catalyst and temperature are optimised.