Radhakrishnan, T. S. ; Savithri, H. S. ; Rao, N. A. ; Venkitasubramanian, T. A. (1988) A Ca2+ sensitive cyclic, 3', 5' nucleotide phosphodiesterase from sheep lung modulated by a tightly bound endogenous calmodulin Biochemistry International, 17 (5). pp. 919-925. ISSN 0158-5231
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Abstract
Highly purified sheep lung cyclic-3',5'-nucleotide phosphodiesterase was sensitive to Ca2+/EGTA but insensitive to exogenous calmodulin. The Ca2+-sensitivity was inhibited by trifluoperazine. Heat-treated enzyme could activate a calmodulin-deficient phosphodiesterase, suggesting the presence of endogenous calmodulin in sheep lung cyclic-3',5'-nucleotide phosphodiesterase, possibly associated with the enzyme in a Ca2+-independent manner.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to International Union of Biochemistry by Academic Press. |
| ID Code: | 85225 |
| Deposited On: | 01 Mar 2012 09:19 |
| Last Modified: | 13 Jul 2012 08:20 |
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