D'Souza, Doris ; Thomas, I. M. ; Das, B. C. (1988) Variation in spontaneous chromosomal damage as a function of biologic rhythms in women Human Genetics, 79 (1). pp. 83-85. ISSN 0340-6717
Full text not available from this repository.
Official URL: http://www.springerlink.com/content/p7764914017267...
Related URL: http://dx.doi.org/10.1007/BF00291717
Abstract
An unequivocal observation of a higher rate of cellular genetic damage in terms of increased frequencies of sister chromatid exchanges (SCEs) and chromosome aberrations during ovulatory and estrogenic stages as compared with those of progestogenic stage of the menstrual cycle in women and the reported fluctuations in SCEs as a function of time in men indicate that chronobiologic considerations are essential in the design of studies of humans and animal experiments. It seems that female subjects are more influenced by biologic rhythms because of specific hormonal cycles and are sensitive to genetic damage during ovulatory/estrogenic stages of the menstrual cycle.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Springer-Verlag. |
| ID Code: | 8458 |
| Deposited On: | 27 Oct 2010 06:30 |
| Last Modified: | 30 May 2011 08:19 |
Repository Staff Only: item control page
