Chaudhuri, Alok Ghosh ; Bhattacharya, Jayanta ; Balakrish Nair, G. ; Takeda, Tae ; Chakrabarti, Manoj K. (1998) Rise of cytosolic Ca2+ and activation of membrane-bound guanylyl cyclase activity in rat enterocytes by heat-stable enterotoxin of Vibrio cholerae non-01 FEMS Microbiology Letters, 160 (1). pp. 125-129. ISSN 1574-6968
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Official URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1574-...
Related URL: http://dx.doi.org/10.1111/j.1574-6968.1998.tb12901.x
Abstract
The cytosolic calcium level ([Ca2+]i) and the membrane-bound guanylyl cyclase activity in the isolated rat intestinal epithelial cells were investigated. Heat-stable enterotoxin of Vibrio cholerae non-01 (NAG-ST) was found to increase both the [Ca2+]i and the enzyme activity. These changes occur similarly until 5 min of incubation with NAG-ST, indicating that these changes might be involved in NAG-ST induced signal transduction in rat enterocytes.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons. |
| Keywords: | Vibrio Cholerae Non-01; Heat-stable Enterotoxin; Intracellular Calcium Ion Concentration; Guanylyl Cyclase; Epithelial cell |
| ID Code: | 84264 |
| Deposited On: | 24 Feb 2012 15:39 |
| Last Modified: | 24 Feb 2012 15:39 |
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