Baranwal, Somesh ; Dey, Keya ; Ramamurthy, T. ; Balakrish Nair, G. ; Kundu, Manikuntala (2002) Role of active efflux in association with target gene mutations in fluoroquinolone resistance in clinical isolates of Vibrio cholerae Antimicrobial Agents and Chemotherapy, 46 (8). pp. 2676-2678. ISSN 1098-6596
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Official URL: http://aac.asm.org/content/46/8/2676.abstract
Related URL: http://dx.doi.org/10.1128/AAC.46.8.2676-2678.2002
Abstract
Quinolones are among the drugs of choice in the management of cholera caused by Vibrio cholerae. In this study, we demonstrate that, in addition to mutations detected in the target genes gyrA and parC, proton motive force-dependent efflux is involved in quinolone resistance in clinical isolates of V. cholerae
Item Type: | Article |
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Source: | Copyright of this article belongs to American Society for Microbiology. |
ID Code: | 83972 |
Deposited On: | 23 Feb 2012 12:53 |
Last Modified: | 23 Feb 2012 12:53 |
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