UV excited autofluorescence spectroscopy of human breast tissue for discriminating cancerous tissue from benign tumor and normal tissue

Abstract

Results of an in-vitro excitation-emission spectroscopic study of human breast tissues are presented. These suggest a significant variation in the concentration of prominent fluorophores in the cancerous, benign tumor and normal tissues. These findings can qualitatively account for the authors' earlier observations of large differences in the relative fluorescence yield of the three tissue types with 300 and 337 nm excitations.