Dasgupta, Raktim ; Verma, Ravi Shanker ; Ahlawat, Sunita ; Uppal, Abha ; Gupta, Pradeep Kumar (2011) Studies on erythrocytes in malaria infected blood sample with Raman optical tweezers Journal of Biomedical Optics, 16 (7). 077009-077009. ISSN 1083-3668
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Official URL: http://spiedigitallibrary.org/jbo/resource/1/jbopf...
Related URL: http://dx.doi.org/10.1117/1.3600011
Abstract
Raman spectroscopy was performed on optically trapped red blood cells (RBCs) from blood samples of healthy volunteers (h-RBCs) and from patients suffering from P. vivax infection (m-RBCs). A significant fraction of m-RBCs produced Raman spectra with altered characteristics relative to h-RBCs. The observed spectral changes suggest a reduced oxygen-affinity or right shifting of the oxygen-dissociation curve for the intracellular hemoglobin in a significant fraction of m-RBCs with respect to its normal functional state.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to The International Society for Optical Engineering. |
| ID Code: | 83449 |
| Deposited On: | 21 Feb 2012 13:01 |
| Last Modified: | 21 Feb 2012 13:01 |
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