C3 - Symmetric proline-functionalized organocatalysts: enantioselective Michael addition reactions

Moorthy, Jarugu Narasimha ; Saha, Satyajit (2010) C3 - Symmetric proline-functionalized organocatalysts: enantioselective Michael addition reactions European Journal of Organic Chemistry, 2010 (33). pp. 6359-6365. ISSN 1434-193X

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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/ejoc.20...

Related URL: http://dx.doi.org/10.1002/ejoc.201000569

Abstract

C3-Symmetric, tripodal catalyst 4 based on 1,3,5-triethylbenzene, which incorporates the features of a molecular receptor, is shown to catalyze Michael addition reactions ofcarbonyl compounds to β -nitrostyrenes in a high stereoselectivity (up to 99:1 dr and up to 98 % ee).

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons.
Keywords:Asymmetric Synthesis; Michael Addition; Organocatalysis; Amino Acids
ID Code:81850
Deposited On:08 Feb 2012 12:40
Last Modified:08 Feb 2012 12:40

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